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PTGDS elisa kit :: Rat prostaglandin D2 synthase 21kDa (brain) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS917167
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

prostaglandin D2 synthase 21kDa (brain) (PTGDS), ELISA Kit

★Popular Item★
 Also Known As   

Rat Prostaglandin-H2 D-isomerase, PTGDS ELISA Kit

 Product Synonym Names    Rat Prostaglandin-H2 D-isomerase (PTGDS) ELISA kit; RP11-229P13.6; L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2; PGD2 synthase; beta-trace protein; glutathione-independent PGD synthase; lipocalin-type prostaglandin D synthase; prostaglandin D synthase; prostagla; prostaglandin D2 synthase 21kDa (brain)
 Product Gene Name   

PTGDS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS917167 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for P22057
 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of rat PTGDS. No significant cross-reactivity or interference between rat PTGDS and analogues was observed.
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 Samples    Serum, plasma, cerebrospinal fluid (CSF), tissue homogenates
 Assay Type    Quantitative Sandwich
 Detection Range    9.37 ng/ml -600 ng/ml
 Sensitivity    Typically less than 2.34 ng/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTGDS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTGDS purchase    MBS917167 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the prostaglandin D2 synthase 21kDa (brain) (PTGDS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 9.37 ng/ml -600 ng/ml in biological research samples containing PTGDS, with an estimated sensitivity of Typically less than 2.34 ng/ml. The ELISA analytical biochemical technique of the MBS917167 kit is based on PTGDS antibody-PTGDS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTGDS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTGDS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cerebrospinal fluid (CSF), tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for PTGDS elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PTGDS has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PTGDS present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PTGDS is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PTGDS bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of PTGDS elisa kit    PTGDS elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS917167. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PTGDS. It may not necessarily be applicable to this product.
 NCBI GI #    6981430
 NCBI GeneID    25526
 NCBI Accession #    NP_037147.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013015.2 [Other Products]
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 UniProt Primary Accession #    P22057 [Other Products]
 UniProt Related Accession #    P22057 [Other Products]
 Molecular Weight    21,301 Da
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 NCBI Official Full Name    prostaglandin-H2 D-isomerase
 NCBI Official Synonym Full Names    prostaglandin D2 synthase (brain)
 NCBI Official Symbol    Ptgds [Similar Products]
 NCBI Official Synonym Symbols   
PH2DISO
[Similar Products]
 NCBI Protein Information    prostaglandin-H2 D-isomerase; PGDS; PGDS2; PGD2 synthase; Prostaglandin D synthase; prostaglandin-D2 synthase; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin-D synthase
 UniProt Protein Name    Prostaglandin-H2 D-isomerase
 UniProt Synonym Protein Names   
Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; Prostaglandin-D2 synthase; PGD2 synthase; PGDS; PGDS2
 Protein Family    Prostaglandin-H2 D-isomerase
 UniProt Gene Name    Ptgds [Similar Products]
 UniProt Synonym Gene Names    PGD2 synthase; PGDS; PGDS2 [Similar Products]
 UniProt Entry Name    PTGDS_RAT
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 NCBI Summary for PTGDS    catalyzes conversion of prostaglandin H2 to prostaglandin D2, a major prostaglandin that mediates sleep, body temperature, hormone release, and odor responses [RGD, Feb 2006]
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 UniProt Comments for PTGDS    Function: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.4 PublicationsManual assertion based on experiment in:Ref.8

Catalytic activity: (5Z,13E,15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E,15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
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 Research Articles on PTGDS    1. Anorectic tumor-bearing rats do not display the changes in ventral striatal prostaglandin D synthase expression observed in food-restricted weight-matched animals.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PTGDS elisa kitDiseases associated with PTGDS elisa kit
 Products by Pathway  Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Arachidonic Acid Metabolism Pathway antibodies  Arachidonic Acid Metabolism Pathway Diagram
 Eicosanoid Synthesis Pathway antibodies  Eicosanoid Synthesis Pathway Diagram
 Folic Acid Network Pathway antibodies  Folic Acid Network Pathway Diagram
 Prostaglandin Synthesis And Regulation Pathway antibodies  Prostaglandin Synthesis And Regulation Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with PTGDS and Neoplasms
 Brain Diseases Antibodies  >2 publications with PTGDS and Brain Diseases
 Mood Disorders Antibodies  >1 publications with PTGDS and Mood Disorders
 Breast Neoplasms Antibodies  >1 publications with PTGDS and Breast Neoplasms
 Depressive Disorder Antibodies  >1 publications with PTGDS and Depressive Disorder
 Skin Diseases Antibodies  >1 publications with PTGDS and Skin Diseases
 Pain Antibodies  >1 publications with PTGDS and Pain
 Hyperplasia Antibodies  >1 publications with PTGDS and Hyperplasia
 Drug Toxicity Antibodies  >1 publications with PTGDS and Drug Toxicity
 Nervous System Malformations Antibodies  >1 publications with PTGDS and Nervous System Malformations
Organs/Tissues associated with PTGDS elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with PTGDS and Brain
 Connective Tissue Antibodies  >2 publications with PTGDS and Connective Tissue
 Eye Antibodies  >2 publications with PTGDS and Eye
 Prostate Antibodies  >1 publications with PTGDS and Prostate
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