View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List TRAb elisa kit :: Rat thyroid stimulating hormone receptor antidoby, TRAb ELISA Kit Catalog # MBS160439 Unit / Price DISCONTINUEDYou will be redirected to our replacement product Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name thyroid stimulating hormone receptor antidoby, TRAb, ELISA Kit Popular Item Full Product Name Rat thyroid stimulating hormone receptor antidoby, TRAb ELISA Kit Product Gene Name TRAb elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual 3D Structure ModBase 3D Structure for P16473 Species Reactivity Rat Samples Serum, plasma, cell culture supernates, ascites, tissue homogenates or other biological fluids Assay Type Quantitative Sandwich Detection Range 1-400U/ml Sensitivity 0.53U/ml Intra-assay Precision Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision. Intra-Assay: CV<8% Inter-assay Precision Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision. CV(%) = SD/mean x 100. Inter-Assay: CV<10% Preparation and Storage Store at 2 to 8 degree C for 6 months. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of TRAb elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for TRAb purchase MBS160439 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the thyroid stimulating hormone receptor antidoby, TRAb, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TRAb. The ELISA analytical biochemical technique of the MBS160439 kit is based on TRAb antibody-TRAb antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TRAb antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TRAb. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for TRAb elisa kit Intended Uses: This sandwich kit is for the accurate quantitative detection of Rat Thyroid stimulating hormone receptor antidoby (also known as TRAb) in serum, plasma, cell culture supernates, Ascites, tissue homogenates or other biological fluids.Principle of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Rat TRAb antigen. TRAb present in the sample is added and binds to antigen coated on the wells. And then biotinylated Rat TRAb Antigen is added and binds to TRAb in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated TRAb antigen. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Rat TRAb. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm. Typical Testing Data/Standard Curve (for reference only) of TRAb elisa kit TOP Sample Manual Insert of MBS160439. NCBI/Uniprot data below describe general gene information for TRAb. It may not necessarily be applicable to this product. NCBI GI # 38016895 NCBI GeneID 7253 NCBI Accession # AAR07906.1 [Other Products] UniProt Primary Accession # P16473 [Other Products] UniProt Secondary Accession # Q16503; Q8TB90; Q96GT6; Q9P1V4; Q9ULA3; Q9UPH3; A0PJU7; F5GYU5; G3V2A9[Other Products] UniProt Related Accession # P16473[Other Products] Molecular Weight 28,427 Da TOP NCBI Official Full Name thyroid stimulating hormone receptor NCBI Official Synonym Full Names thyroid stimulating hormone receptor NCBI Official Symbol TSHR [Similar Products] NCBI Official Synonym Symbols LGR3; CHNG1; hTSHR-I [Similar Products] NCBI Protein Information thyrotropin receptor UniProt Protein Name Thyrotropin receptor UniProt Synonym Protein Names Thyroid-stimulating hormone receptor; TSH-R Protein Family Protein UniProt Gene Name TSHR [Similar Products] UniProt Synonym Gene Names LGR3; TSH-R [Similar Products] TOP NCBI Summary for TRAb The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] TOP UniProt Comments for TRAb Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed:11847099, PubMed:12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin (PubMed:12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed:11847099). Plays a central role in controlling thyroid cell metabolism (). Research Articles on TRAb 1. TSHR mutations occur in approximately 5% thyroid nodules in a large consecutive series with indeterminate cytology. TSHR mutations may be associated with an increased cancer risk when present at high allelic frequency TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with TRAb elisa kit Reference Product PubMed Publications GNAS elisa kit >14 publications with TRAb and GNAS TSHB elisa kit >7 publications with TRAb and TSHB LHCGR elisa kit >5 publications with TRAb and LHCGR NKX2-1 elisa kit >4 publications with TRAb and NKX2-1 CALCA elisa kit >2 publications with TRAb and CALCA PTH elisa kit >2 publications with TRAb and PTH POMC elisa kit >1 publications with TRAb and POMC Pathways associated with TRAb elisa kit Products by Pathway Pathway Diagram Arf6 Signaling Events Pathway antibodies Arf6 Signaling Events Pathway Diagram Arf6 Trafficking Events Pathway antibodies Arf6 Trafficking Events Pathway Diagram Autoimmune Thyroid Disease Pathway antibodies Autoimmune Thyroid Disease Pathway Diagram Autoimmune Thyroid Disease Pathway antibodies Autoimmune Thyroid Disease Pathway Diagram Class A/1 (Rhodopsin-like Receptors) Pathway antibodies Class A/1 (Rhodopsin-like Receptors) Pathway Diagram G Alpha (s) Signalling Events Pathway antibodies G Alpha (s) Signalling Events Pathway Diagram GPCR Downstream Signaling Pathway antibodies GPCR Downstream Signaling Pathway Diagram GPCR Ligand Binding Pathway antibodies GPCR Ligand Binding Pathway Diagram Hormone Ligand-binding Receptors Pathway antibodies Hormone Ligand-binding Receptors Pathway Diagram Neuroactive Ligand-receptor Interaction Pathway antibodies Neuroactive Ligand-receptor Interaction Pathway Diagram Diseases associated with TRAb elisa kit Disease Name Pubmed Publications Hyperthyroidism Antibodies >462 publications with TRAb and Hyperthyroidism Graves Disease Antibodies >426 publications with TRAb and Graves Disease Thyroid Neoplasms Antibodies >153 publications with TRAb and Thyroid Neoplasms Thyroiditis, Autoimmune Antibodies >96 publications with TRAb and Thyroiditis, Autoimmune Carcinoma Antibodies >88 publications with TRAb and Carcinoma Congenital Hypothyroidism Antibodies >66 publications with TRAb and Congenital Hypothyroidism Adenoma Antibodies >47 publications with TRAb and Adenoma Thyrotoxicosis Antibodies >38 publications with TRAb and Thyrotoxicosis Kidney Diseases Antibodies >34 publications with TRAb and Kidney Diseases Hyperthyroidism, Nonautoimmune Antibodies >34 publications with TRAb and Hyperthyroidism, Nonautoimmune Organs/Tissues associated with TRAb elisa kit Organ/Tissue Name Pubmed Publications Thyroid Antibodies >956 publications with TRAb and Thyroid Blood Antibodies >317 publications with TRAb and Blood Ovary Antibodies >74 publications with TRAb and Ovary Connective Tissue Antibodies >52 publications with TRAb and Connective Tissue Muscle Antibodies >37 publications with TRAb and Muscle Brain Antibodies >26 publications with TRAb and Brain Thymus Antibodies >12 publications with TRAb and Thymus Lung Antibodies >10 publications with TRAb and Lung Embryonic Tissue Antibodies >6 publications with TRAb and Embryonic Tissue Placenta Antibodies >2 publications with TRAb and Placenta TOP © 2006-24 MyBioSource.com. 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