NP_037002.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
46,192 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 11B
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 11b
NCBI Official Synonym Symbols
NCBI Protein Information
tumor necrosis factor receptor superfamily member 11B; Osteoprotegerin
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 11B
UniProt Synonym Protein Names
Osteoprotegerin
UniProt Synonym Gene Names
UniProt Entry Name
TR11B_RAT
NCBI Summary for TNFRSF11B
plays a role in the negative regulation of bone resorption by inhibiting formation of osteoclasts [RGD, Feb 2006]
UniProt Comments for TNFRSF11B
Function: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis
Research Articles on TNFRSF11B
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Products associated with TNFRSF11B elisa kit
Pathways associated with TNFRSF11B elisa kit
Diseases associated with TNFRSF11B elisa kit
Organs/Tissues associated with TNFRSF11B elisa kit
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