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ERBB3 elisa kit :: Rat v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS935230 ERBB3 elisa kit
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3), ELISA Kit

 Also Known As   

Rat Receptor tyrosine-protein kinase erbB-3, ERBB3 ELISA Kit

 Product Synonym Names    Rat Receptor tyrosine-protein kinase erbB-3 (ERBB3) ELISA kit; ErbB-3; HER3; LCCS2; MDA-BF-1; MGC88033; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3; erbB-3; receptor tyrosine-protein kinase erbB-3; v-erb-b2 avian erythroblastic leukemia viral o; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
 Product Gene Name   

ERBB3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q62799
 Species Reactivity    Rat
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 Specificity    This assay has high sensitivity and excellent specificity for detection of rat ERBB3. No significant cross-reactivity or interference between rat ERBB3 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, Cell lysates
 Assay Type    Sandwich
 Detection Range    0.156 ng/ml-10 ng/ml.
 Sensitivity    The minimum detectable dose of rat ERBB3 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ERBB3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ERBB3 purchase    MBS935230 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (ERBB3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml-10 ng/ml in biological research samples containing ERBB3, with an estimated sensitivity of The minimum detectable dose of rat ERBB3 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. The ELISA analytical biochemical technique of the MBS935230 kit is based on ERBB3 antibody-ERBB3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ERBB3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ERBB3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, Cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for ERBB3 elisa kit

   Principle of the assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ERBB3 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ERBB3 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ERBB3 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ERBB3 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS935230. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ERBB3. It may not necessarily be applicable to this product.
 NCBI GI #    17432904
 NCBI GeneID    29496
 NCBI Accession #    NP_058914.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_017218.3 [Other Products]
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 UniProt Primary Accession #    Q62799 [Other Products]
 UniProt Secondary Accession #    Q62955 [Other Products]
 UniProt Related Accession #    Q62799 [Other Products]
 Molecular Weight    147,546 Da
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 NCBI Official Full Name    receptor tyrosine-protein kinase erbB-3
 NCBI Official Synonym Full Names    v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
 NCBI Official Symbol    Erbb3 [Similar Products]
 NCBI Official Synonym Symbols   
nuc-ErbB3
[Similar Products]
 NCBI Protein Information    receptor tyrosine-protein kinase erbB-3; c-erbB3; c-erbB-3; avian erythroblastosis oncogene B 3; proto-oncogene-like protein c-ErbB-3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
 UniProt Protein Name    Receptor tyrosine-protein kinase erbB-3
 UniProt Synonym Protein Names   
Proto-oncogene-like protein c-ErbB-3
 Protein Family    Receptor tyrosine-protein kinase
 UniProt Gene Name    Erbb3 [Similar Products]
 UniProt Entry Name    ERBB3_RAT
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 NCBI Summary for ERBB3    acts as a tyrosine kinase receptor for neuregulin; may play a role in axonal regeneration in response to injury [RGD, Feb 2006]
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 UniProt Comments for ERBB3    HER3: a receptor tyrosine kinase of the EGFR family. Binds and is activated by neuregulins and NTAK. Can form homodimers or ErbB-2/ErbB-3 heterodimers. Kinase domain lacks activity but heterodimerizes with other EGFRs to transduce growth signals. May be required for HER2 activity. Elevated expression in breast and other tumors is indicative of poor outcome. A secreted form is expressed in metastatic prostate cancer Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, TK; EC 2.7.10.1; Oncoprotein; Protein kinase, tyrosine (receptor); Kinase, protein; Membrane protein, integral; TK group; EGFR family

Cellular Component: postsynaptic membrane; extracellular space; basolateral plasma membrane; apical plasma membrane; integral to membrane; nucleus; lateral plasma membrane; receptor complex

Molecular Function: identical protein binding; protein heterodimerization activity; protein-tyrosine kinase activity; growth factor binding; protein tyrosine kinase activator activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; ATP binding

Biological Process: circadian rhythm; epidermal growth factor receptor signaling pathway; response to drug; tongue development; mammary gland involution; skeletal muscle development; phosphoinositide 3-kinase cascade; peptidyl-tyrosine phosphorylation; cranial nerve development; negative regulation of cell adhesion; signal transduction; regulation of cell proliferation; negative regulation of signal transduction; peripheral nervous system development; Schwann cell differentiation; odontogenesis; positive regulation of glucose import; neuron apoptosis; axonogenesis; cellular response to insulin stimulus; response to wounding; negative regulation of secretion; negative regulation of neuron apoptosis; transmembrane receptor protein tyrosine kinase signaling pathway
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 Research Articles on ERBB3    1. we demonstrated the involvement of ErbB receptors in the regulation of neurite elongation and sodium current induction in PC12 cells
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ERBB3 elisa kitPathways associated with ERBB3 elisa kit
 Reference Product  PubMed Publications
 Ptpn11 elisa kit  >8 publications with ERBB3 and Ptpn11
 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 ErbB Signaling Pathway antibodies  ErbB Signaling Pathway Diagram
 IL-6 Signaling Pathway antibodies  IL-6 Signaling Pathway Diagram
Diseases associated with ERBB3 elisa kitOrgans/Tissues associated with ERBB3 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >419 publications with ERBB3 and Neoplasms
 Carcinoma Antibodies  >176 publications with ERBB3 and Carcinoma
 Breast Neoplasms Antibodies  >162 publications with ERBB3 and Breast Neoplasms
 Skin Diseases Antibodies  >149 publications with ERBB3 and Skin Diseases
 Adenocarcinoma Antibodies  >69 publications with ERBB3 and Adenocarcinoma
 Lung Neoplasms Antibodies  >55 publications with ERBB3 and Lung Neoplasms
 Nervous System Diseases Antibodies  >54 publications with ERBB3 and Nervous System Diseases
 Neoplasms, Experimental Antibodies  >50 publications with ERBB3 and Neoplasms, Experimental
 Prostatic Diseases Antibodies  >35 publications with ERBB3 and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >35 publications with ERBB3 and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >110 publications with ERBB3 and Nerve
 Lung Antibodies  >82 publications with ERBB3 and Lung
 Brain Antibodies  >67 publications with ERBB3 and Brain
 Prostate Antibodies  >46 publications with ERBB3 and Prostate
 Colon Antibodies  >31 publications with ERBB3 and Colon
 Pancreas Antibodies  >11 publications with ERBB3 and Pancreas
 Placenta Antibodies  >8 publications with ERBB3 and Placenta
 Small Intestine Antibodies  >4 publications with ERBB3 and Small Intestine
 Mixed Antibodies  >1 publications with ERBB3 and Mixed
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