NP_055688.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
43,089 Da
NCBI Official Full Name
acyl-CoA:lysophosphatidylglycerol acyltransferase 1
NCBI Official Synonym Full Names
lysophosphatidylglycerol acyltransferase 1
NCBI Protein Information
acyl-CoA:lysophosphatidylglycerol acyltransferase 1; family with sequence similarity 34, member A
UniProt Protein Name
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1
UniProt Synonym Gene Names
UniProt Entry Name
LGAT1_HUMAN
NCBI Summary for LPGAT1
Acyl-CoA:lysophosphatidylglycerol (LPG) acyltransferase catalyzes the reacylation of LPG to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin (Yang et al., 2004 [PubMed 15485873]).[supplied by OMIM, Mar 2008]
UniProt Comments for LPGAT1
LPGAT1: Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Protein type: Membrane protein, integral; Transferase; EC 2.3.1.-; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1q32
Cellular Component: endoplasmic reticulum membrane; membrane; cytoplasm; integral to membrane
Molecular Function: transferase activity, transferring acyl groups
Biological Process: phospholipid metabolic process; glycerophospholipid biosynthetic process
Research Articles on LPGAT1
Precautions
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Pathways associated with LPGAT1 elisa kit
Diseases associated with LPGAT1 elisa kit
Organs/Tissues associated with LPGAT1 elisa kit
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