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AZU1 elisa kit :: Sheep Azurocidin 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS044058 AZU1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Azurocidin 1 (AZU1), ELISA Kit

 Also Known As   

Sheep Azurocidin 1 ELISA Kit

 Product Gene Name   

AZU1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    162815
 3D Structure    ModBase 3D Structure for P20160
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 Species Reactivity    Sheep
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AZU1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AZU1 purchase    MBS044058 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Azurocidin 1 (AZU1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AZU1. The ELISA analytical biochemical technique of the MBS044058 kit is based on AZU1 antibody-AZU1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AZU1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AZU1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AZU1. It may not necessarily be applicable to this product.
 NCBI GI #    11342670
 NCBI GeneID    566
 NCBI Accession #    NP_001691.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001700.3 [Other Products]
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 UniProt Primary Accession #    P20160 [Other Products]
 UniProt Secondary Accession #    P80014; Q52LG4; Q9UCM1; Q9UCT5 [Other Products]
 UniProt Related Accession #    P20160 [Other Products]
 Molecular Weight    26,886 Da
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 NCBI Official Full Name    azurocidin preproprotein
 NCBI Official Synonym Full Names    azurocidin 1
 NCBI Official Symbol    AZU1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    azurocidin; neutrophil azurocidin; heparin-binding protein; cationic antimicrobial protein 37; cationic antimicrobial protein CAP37
 UniProt Protein Name    Azurocidin
 UniProt Synonym Protein Names   
Cationic antimicrobial protein CAP37; Heparin-binding protein
 Protein Family    Azurocidin
 UniProt Gene Name    AZU1 [Similar Products]
 UniProt Synonym Gene Names    HBP [Similar Products]
 UniProt Entry Name    CAP7_HUMAN
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 NCBI Summary for AZU1    Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. The protein encoded by this gene is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AZU1    AZU1: This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram- negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G. Belongs to the peptidase S1 family. Elastase subfamily.

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: azurophil granule; extracellular region

Molecular Function: heparin binding; toxin binding; serine-type endopeptidase activity

Biological Process: positive regulation of tumor necrosis factor biosynthetic process; positive regulation of cell adhesion; microglial cell activation; proteolysis; defense response to Gram-negative bacterium; glial cell migration; macrophage chemotaxis; induction of positive chemotaxis; monocyte activation; cellular extravasation; positive regulation of MHC class II biosynthetic process; positive regulation of phagocytosis; protein kinase C activation; positive regulation of fractalkine biosynthetic process; positive regulation of interleukin-1 beta biosynthetic process; protein processing; immune response; regulation of vascular permeability; inflammatory response; negative regulation of apoptosis
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 Research Articles on AZU1    1. AZU1 exhibited high affinity binding to PTX3 in a calcium ion-dependent manner
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AZU1 elisa kitDiseases associated with AZU1 elisa kit
 Reference Product  PubMed Publications
 BPI elisa kit  >2 publications with AZU1 and BPI
 MPO elisa kit  >1 publications with AZU1 and MPO
 ELANE elisa kit  >1 publications with AZU1 and ELANE
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with AZU1 and Neoplasms
 Lung Diseases Antibodies  >2 publications with AZU1 and Lung Diseases
 Inflammation Antibodies  >1 publications with AZU1 and Inflammation
Organs/Tissues associated with AZU1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with AZU1 and Blood
 Bone Marrow Antibodies  >1 publications with AZU1 and Bone Marrow
 Bone Antibodies  >1 publications with AZU1 and Bone
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