AAB25452.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
19,746 Da
NCBI Official Full Name
betacellulin
NCBI Official Synonym Full Names
betacellulin
NCBI Protein Information
probetacellulin
UniProt Protein Name
Probetacellulin
UniProt Synonym Gene Names
UniProt Entry Name
BTC_HUMAN
NCBI Summary for BTC
The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. [provided by RefSeq, Jul 2008]
UniProt Comments for BTC
BTC: Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Protein type: Ligand, receptor tyrosine kinase; Membrane protein, integral; Cell cycle regulation
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: extracellular space; plasma membrane; integral to membrane; extracellular region
Molecular Function: protein binding; growth factor activity; epidermal growth factor receptor binding
Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of fibroblast proliferation; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; positive regulation of mitosis; nerve growth factor receptor signaling pathway; positive regulation of cell proliferation; innate immune response; positive regulation of cell differentiation; negative regulation of apoptosis
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Pathways associated with BTC elisa kit
Diseases associated with BTC elisa kit
Organs/Tissues associated with BTC elisa kit
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