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CLDN1 elisa kit :: Sheep Claudin 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS737793 CLDN1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Claudin 1 (CLDN1), ELISA Kit

 Also Known As   

Sheep Claudin 1 ELISA Kit

 Product Gene Name   

CLDN1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Manual Insert    Request Manual
 OMIM    gene 607626
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 Species Reactivity    Sheep
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact technical support.
 Other Notes    Small volumes of CLDN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CLDN1 purchase    MBS737793 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Claudin 1 (CLDN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CLDN1. The ELISA analytical biochemical technique of the MBS737793 kit is based on CLDN1 antibody-CLDN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CLDN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CLDN1. Appropriate sample types may include undiluted human body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for CLDN1 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for CLDN1. It may not necessarily be applicable to this product.
 NCBI GI #    10863887
 NCBI GeneID    9076
 NCBI Accession #    NP_066924.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021101.4 [Other Products]
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 UniProt Related Accession #    O95832 [Other Products]
 Molecular Weight    22,744 Da
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 NCBI Official Full Name    claudin-1
 NCBI Official Synonym Full Names    claudin 1
 NCBI Official Symbol    CLDN1 [Similar Products]
 NCBI Official Synonym Symbols   
CLD1; SEMP1; ILVASC
[Similar Products]
 NCBI Protein Information    claudin-1; senescence-associated epithelial membrane protein 1
 UniProt Protein Name    Claudin-1
 UniProt Synonym Protein Names   
Senescence-associated epithelial membrane protein
 Protein Family    Claudin
 UniProt Gene Name    CLDN1 [Similar Products]
 UniProt Synonym Gene Names    CLD1; SEMP1; UNQ481/PRO944 [Similar Products]
 UniProt Entry Name    CLD1_HUMAN
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 NCBI Summary for CLDN1    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CLDN1    Claudin-1: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins. Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis. Belongs to the claudin family.

Protein type: Cytoskeletal; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q28-q29

Cellular Component: tight junction; integral to plasma membrane; apical plasma membrane; integral to membrane; lateral plasma membrane

Molecular Function: identical protein binding; protein binding; structural molecule activity

Biological Process: intercellular junction assembly and maintenance; viral reproduction; cell adhesion; calcium-independent cell-cell adhesion

Disease: Ichthyosis, Leukocyte Vacuoles, Alopecia, And Sclerosing Cholangitis
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 Research Articles on CLDN1    1. Low CLDN1 expression is associated with adamantinomatous Craniopharyngioma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to Sheep Claudin 1 ELISA Kit
 Catalog #  Product Name  Catalog #  Product Name
 MBS6008682  Claudin 14, CT (CLDN14, Claudin-14, UNQ777/PRO1571)  MBS002025  Rabbit Claudin 11 Antibody
 MBS007425  Rat Claudin 1 ELISA Kit  MBS2531558  Human CLDN11 (Claudin 11) CLIA Kit
 MBS743393  Goat Claudin 1 ELISA Kit  MBS839510  Claudin 1 antibody
 MBS9414173  claudin 14 antibody  MBS089807  Fish Claudin 11 ELISA Kit
 MBS001802  Rabbit Claudin 10 Antibody  MBS852656  Claudin 10 Antibody
Products associated with CLDN1 elisa kitPathways associated with CLDN1 elisa kit
 Reference Product  PubMed Publications
 OCLN elisa kit  >273 publications with CLDN1 and OCLN
 TJP1 elisa kit  >212 publications with CLDN1 and TJP1
 CLDN5 elisa kit  >124 publications with CLDN1 and CLDN5
 CLDN3 elisa kit  >97 publications with CLDN1 and CLDN3
 CD81 elisa kit  >87 publications with CLDN1 and CD81
 TJP2 elisa kit  >21 publications with CLDN1 and TJP2
 F11R elisa kit  >6 publications with CLDN1 and F11R
 TJP3 elisa kit  >5 publications with CLDN1 and TJP3
 MPDZ elisa kit  >3 publications with CLDN1 and MPDZ
 INADL elisa kit  >2 publications with CLDN1 and INADL
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Hepatitis C Pathway antibodies  Hepatitis C Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Nectin Adhesion Pathway antibodies  Nectin Adhesion Pathway Diagram
Diseases associated with CLDN1 elisa kitOrgans/Tissues associated with CLDN1 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >118 publications with CLDN1 and Inflammation
 Liver Diseases Antibodies  >89 publications with CLDN1 and Liver Diseases
 Necrosis Antibodies  >71 publications with CLDN1 and Necrosis
 Disease Models, Animal Antibodies  >55 publications with CLDN1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >43 publications with CLDN1 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >36 publications with CLDN1 and Carcinoma, Hepatocellular
 Lung Diseases Antibodies  >34 publications with CLDN1 and Lung Diseases
 Liver Neoplasms Antibodies  >30 publications with CLDN1 and Liver Neoplasms
 Kidney Diseases Antibodies  >26 publications with CLDN1 and Kidney Diseases
 Edema Antibodies  >21 publications with CLDN1 and Edema
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >193 publications with CLDN1 and Intestine
 Liver Antibodies  >150 publications with CLDN1 and Liver
 Kidney Antibodies  >108 publications with CLDN1 and Kidney
 Brain Antibodies  >97 publications with CLDN1 and Brain
 Skin Antibodies  >87 publications with CLDN1 and Skin
 Nerve Antibodies  >86 publications with CLDN1 and Nerve
 Lung Antibodies  >66 publications with CLDN1 and Lung
 Eye Antibodies  >42 publications with CLDN1 and Eye
 Mouth Antibodies  >40 publications with CLDN1 and Mouth
 Embryonic Tissue Antibodies  >31 publications with CLDN1 and Embryonic Tissue
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