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CX43 elisa kit :: Sheep Connexin 43 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018459 CX43 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Connexin 43 (CX43), ELISA Kit

 Also Known As   

Sheep Connexin 43 ELISA Kit

 Product Gene Name   

CX43 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 20; NC_007131.5 (40746894..40752184, complement). Location: chromosome: 20
 3D Structure    ModBase 3D Structure for O57474
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 Species Reactivity    Sheep
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CX43 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CX43 purchase    MBS018459 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Connexin 43 (CX43) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CX43. The ELISA analytical biochemical technique of the MBS018459 kit is based on CX43 antibody-CX43 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CX43 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CX43. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CX43. It may not necessarily be applicable to this product.
 NCBI GI #    29179440
 NCBI GeneID    30236
 NCBI Accession #    AAH49297.1 [Other Products]
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 UniProt Primary Accession #    O57474 [Other Products]
 UniProt Secondary Accession #    Q5TYN6; Q7ZTS1 [Other Products]
 UniProt Related Accession #    O57474 [Other Products]
 Molecular Weight    43,455 Da
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 NCBI Official Full Name    Cx43 protein
 NCBI Official Synonym Full Names    connexin 43
 NCBI Official Symbol    cx43 [Similar Products]
 NCBI Official Synonym Symbols   
gja1; cx43a1; zfCx43.3
[Similar Products]
 NCBI Protein Information    gap junction alpha-1 protein; shf; sof; connexin-43; etID309742.9; short fin protein; gap junction protein, alpha 1
 UniProt Protein Name    Gap junction alpha-1 protein
 UniProt Synonym Protein Names   
Connexin-43; Cx43; Short fin protein
 UniProt Gene Name    gja1 [Similar Products]
 UniProt Synonym Gene Names    cx43; shf; sof; Cx43 [Similar Products]
 UniProt Entry Name    CXA1_DANRE
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 UniProt Comments for CX43    Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Ref.1Plays a role in regulation of fin bone size and growth. Ref.1

Subunit structure: A connexon is composed of a hexamer of connexins.

Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction › gap junction.

Tissue specificity: Expressed in adult ovary, heart, lens and liver. In growing caudal fins, expressed in cells flanking the germinal region of newly growing segments and in osteoblasts at segment boundaries. Ref.1 Ref.2 Ref.5

Developmental stage: Expressed both maternally and zygotically. Zygotic expression is initiated before gastrulation and persists through to day 5 of development. Levels increase in late somitogenesis, and late embryonic and early larval stages. Embryonic expression is observed in many developing tissues and organs, including the notochord and brain, and heart and vasculature. Detected throughout the lens at 24 hours post-fertilization (hpf), but by 3-4 days development, restricted to the lateral epithelium and differentiating cells in the equatorial region. Ref.2 Ref.5

Miscellaneous: Morpholino knockdown of the protein results in heart folding defects, reduced hematopoiesis and small eyes.

Sequence similarities: Belongs to the connexin family. Alpha-type (group II) subfamily.
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 Research Articles on CX43    1. Sema3d functions in a common molecular pathway with Cx43 cell proliferation and joint formation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CX43 elisa kitDiseases associated with CX43 elisa kit
 Products by Pathway  Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Formation Of Annular Gap Junctions Pathway antibodies  Formation Of Annular Gap Junctions Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Pathway antibodies  Gap Junction Pathway Diagram
 Gap Junction Assembly Pathway antibodies  Gap Junction Assembly Pathway Diagram
 Gap Junction Degradation Pathway antibodies  Gap Junction Degradation Pathway Diagram
 Gap Junction Trafficking Pathway antibodies  Gap Junction Trafficking Pathway Diagram
 Gap Junction Trafficking And Regulation Pathway antibodies  Gap Junction Trafficking And Regulation Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >258 publications with CX43 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >178 publications with CX43 and Congenital Abnormalities
 Hypertrophy Antibodies  >135 publications with CX43 and Hypertrophy
 Fibrosis Antibodies  >134 publications with CX43 and Fibrosis
 Necrosis Antibodies  >99 publications with CX43 and Necrosis
 Heart Defects, Congenital Antibodies  >87 publications with CX43 and Heart Defects, Congenital
 Abnormalities, Multiple Antibodies  >62 publications with CX43 and Abnormalities, Multiple
 Liver Diseases Antibodies  >54 publications with CX43 and Liver Diseases
 Eye Abnormalities Antibodies  >48 publications with CX43 and Eye Abnormalities
 Craniofacial Abnormalities Antibodies  >42 publications with CX43 and Craniofacial Abnormalities
Organs/Tissues associated with CX43 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1402 publications with CX43 and Muscle
 Brain Antibodies  >516 publications with CX43 and Brain
 Bone Antibodies  >364 publications with CX43 and Bone
 Eye Antibodies  >331 publications with CX43 and Eye
 Liver Antibodies  >263 publications with CX43 and Liver
 Reproductive System Antibodies  >44 publications with CX43 and Reproductive System
 Whole Body Antibodies  >10 publications with CX43 and Whole Body
 Fin Antibodies  >8 publications with CX43 and Fin
 Uncharacterized Tissue Antibodies  >2 publications with CX43 and Uncharacterized Tissue
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