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ITM2C elisa kit :: Sheep Integral membrane protein 2C (ITM2C) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7237613 ITM2C elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Integral membrane protein 2C (ITM2C), ELISA Kit

 Also Known As   

Sheep Integral membrane protein 2C (ITM2C) ELISA Kit

 Product Gene Name   

ITM2C elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    609554
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 Species Reactivity    Sheep
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ITM2C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ITM2C purchase    MBS7237613 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Integral membrane protein 2C (ITM2C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ITM2C. The ELISA analytical biochemical technique of the MBS7237613 kit is based on ITM2C antibody-ITM2C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ITM2C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ITM2C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for ITM2C elisa kit    Neurobiology
NCBI/Uniprot data below describe general gene information for ITM2C. It may not necessarily be applicable to this product.
 NCBI GI #    71051317
 NCBI GeneID    81618
 NCBI Accession #    AAH98563.1 [Other Products]
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 UniProt Secondary Accession #    Q4G0A8; Q53H84; Q6IAE7; Q86VK5; Q8N288; Q8TAW0; Q9BUP8; B3KPG4 [Other Products]
 UniProt Related Accession #    Q9NQX7 [Other Products]
 Molecular Weight    25,921 Da
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 NCBI Official Full Name    Integral membrane protein 2C
 NCBI Official Synonym Full Names    integral membrane protein 2C
 NCBI Official Symbol    ITM2C [Similar Products]
 NCBI Official Synonym Symbols   
E25; BRI3; E25C; ITM3; BRICD2C
[Similar Products]
 NCBI Protein Information    integral membrane protein 2C; cerebral protein 14; transmembrane protein BRI3; integral membrane protein 3; BRICHOS domain containing 2C
 UniProt Protein Name    Integral membrane protein 2C
 UniProt Synonym Protein Names   
Cerebral protein 14; Transmembrane protein BRI3Cleaved into the following chain:CT-BRI3
 Protein Family    Integral membrane protein
 UniProt Gene Name    ITM2C [Similar Products]
 UniProt Synonym Gene Names    BRI3; hucep-14; NPD018; PSEC0047 [Similar Products]
 UniProt Entry Name    ITM2C_HUMAN
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 UniProt Comments for ITM2C    ITM2C: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. Belongs to the ITM2 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: Golgi apparatus; lysosomal membrane; perinuclear region of cytoplasm; lysosome; plasma membrane; integral to membrane

Molecular Function: protein binding; beta-amyloid binding; ATP binding

Biological Process: neuron differentiation
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 Research Articles on ITM2C    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with ITM2C elisa kitOrgans/Tissues associated with ITM2C elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >2 publications with ITM2C and Nervous System Diseases
 Intracranial Hemorrhages Antibodies  >1 publications with ITM2C and Intracranial Hemorrhages
 Cardiovascular Diseases Antibodies  >1 publications with ITM2C and Cardiovascular Diseases
 Neurobehavioral Manifestations Antibodies  >1 publications with ITM2C and Neurobehavioral Manifestations
 Disease Models, Animal Antibodies  >1 publications with ITM2C and Disease Models, Animal
 Brain Diseases Antibodies  >1 publications with ITM2C and Brain Diseases
 Learning Disorders Antibodies  >1 publications with ITM2C and Learning Disorders
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >4 publications with ITM2C and Nerve
 Brain Antibodies  >3 publications with ITM2C and Brain
 Stomach Antibodies  >2 publications with ITM2C and Stomach
 Bone Antibodies  >2 publications with ITM2C and Bone
 Muscle Antibodies  >1 publications with ITM2C and Muscle
 Ovary Antibodies  >1 publications with ITM2C and Ovary
 Connective Tissue Antibodies  >1 publications with ITM2C and Connective Tissue
 Parathyroid Antibodies  >1 publications with ITM2C and Parathyroid
 Testis Antibodies  >1 publications with ITM2C and Testis
 Kidney Antibodies  >1 publications with ITM2C and Kidney
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