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LCN2 elisa kit :: Sheep LCN2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2508615 LCN2 elisa kit
Unit / Price
48-Strip-Wells  /  $490 +1 FREE 8GB USB
96-Strip-Wells  /  $585 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,475 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,360 +5 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Sheep LCN2 (Lipocalin 2) ELISA Kit

 Product Gene Name   

LCN2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2508615 COA    COA PDF
 OMIM    600181
 3D Structure    ModBase 3D Structure for P80188
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 Species Reactivity    Sheep
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 Specificity    This kit recognizes natural and recombinant Sheep LCN2. No significant cross-reactivity or interference between Sheep LCN2 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    31.25-2000pg/mL
 Sensitivity    18.75pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of LCN2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for LCN2 purchase    MBS2508615 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the LCN2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25-2000pg/mL in biological research samples containing LCN2, with an estimated sensitivity of 18.75pg/mL. The ELISA analytical biochemical technique of the MBS2508615 kit is based on LCN2 antibody-LCN2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LCN2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LCN2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for LCN2 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Sheep LCN2 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to LCN2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for LCN2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain LCN2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of LCN2. You can calculate the concentration of LCN2 in the samples by comparing the OD of the samples to the standard curve.
Sample Manual Insert of MBS2508615. Click to request current manual
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NCBI/Uniprot data below describe general gene information for LCN2. It may not necessarily be applicable to this product.
 NCBI GI #    49457137
 NCBI GeneID    3934
 NCBI Accession #    CAG46889.1 [Other Products]
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 UniProt Primary Accession #    P80188 [Other Products]
 UniProt Secondary Accession #    P30150; Q5SYV9; Q5SYW0; Q6FGL5; Q92683; A6NII8; B4DWV4; B7ZAA2 [Other Products]
 UniProt Related Accession #    P80188 [Other Products]
 Molecular Weight    22,457 Da
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 NCBI Official Full Name    LCN2, partial
 NCBI Official Synonym Full Names    lipocalin 2
 NCBI Official Symbol    LCN2 [Similar Products]
 NCBI Official Synonym Symbols   
24p3; MSFI; NGAL
[Similar Products]
 NCBI Protein Information    neutrophil gelatinase-associated lipocalin; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; lipocalin-2; migration-stimulating factor inhibitor; oncogene 24p3; p25; siderocalin LCN2
 UniProt Protein Name    Neutrophil gelatinase-associated lipocalin
 UniProt Synonym Protein Names   
25 kDa alpha-2-microglobulin-related subunit of MMP-9; Lipocalin-2; Oncogene 24p3; Siderocalin LCN2; p25
 Protein Family    Neutrophil gelatinase-associated lipocalin
 UniProt Gene Name    LCN2 [Similar Products]
 UniProt Synonym Gene Names    HNL; NGAL; NGAL [Similar Products]
 UniProt Entry Name    NGAL_HUMAN
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 UniProt Comments for LCN2    LCN2: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5- DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth. Belongs to the calycin superfamily. Lipocalin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q34

Cellular Component: extracellular space; extracellular region; cytosol

Molecular Function: protein homodimerization activity; protease binding; transporter activity; iron ion binding

Biological Process: response to drug; cellular response to nutrient levels; cellular iron ion homeostasis; response to virus; siderophore transport; positive regulation of cell projection organization and biogenesis; innate immune response; ion transport; response to herbicide; transmembrane transport
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 Research Articles on LCN2    1. Decrease of NGAL expression is associated with metastasis in neoplasms.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with LCN2 elisa kitPathways associated with LCN2 elisa kit
 Reference Product  PubMed Publications
 EGFR elisa kit  >74 publications with LCN2 and EGFR
 MMP9 elisa kit  >21 publications with LCN2 and MMP9
 HMOX1 elisa kit  >15 publications with LCN2 and HMOX1
 PPARG elisa kit  >8 publications with LCN2 and PPARG
 GFAP elisa kit  >3 publications with LCN2 and GFAP
 LIF elisa kit  >2 publications with LCN2 and LIF
 Products by Pathway  Pathway Diagram
 Iron Uptake And Transport Pathway antibodies  Iron Uptake And Transport Pathway Diagram
 Orphan Transporters Pathway antibodies  Orphan Transporters Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with LCN2 elisa kitOrgans/Tissues associated with LCN2 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >610 publications with LCN2 and Kidney Diseases
 Acute Kidney Injury Antibodies  >552 publications with LCN2 and Acute Kidney Injury
 Inflammation Antibodies  >278 publications with LCN2 and Inflammation
 Cardiovascular Diseases Antibodies  >214 publications with LCN2 and Cardiovascular Diseases
 Heart Diseases Antibodies  >112 publications with LCN2 and Heart Diseases
 Necrosis Antibodies  >94 publications with LCN2 and Necrosis
 Disease Models, Animal Antibodies  >87 publications with LCN2 and Disease Models, Animal
 Proteinuria Antibodies  >86 publications with LCN2 and Proteinuria
 Hypertension Antibodies  >68 publications with LCN2 and Hypertension
 Liver Diseases Antibodies  >62 publications with LCN2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >765 publications with LCN2 and Blood
 Kidney Antibodies  >696 publications with LCN2 and Kidney
 Liver Antibodies  >139 publications with LCN2 and Liver
 Lung Antibodies  >75 publications with LCN2 and Lung
 Bone Antibodies  >38 publications with LCN2 and Bone
 Muscle Antibodies  >36 publications with LCN2 and Muscle
 Connective Tissue Antibodies  >33 publications with LCN2 and Connective Tissue
 Bone Marrow Antibodies  >30 publications with LCN2 and Bone Marrow
 Intestine Antibodies  >26 publications with LCN2 and Intestine
 Uterus Antibodies  >21 publications with LCN2 and Uterus
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