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ACADM elisa kit :: Sheep Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7251347 ACADM elisa kit
Unit / Price
48-Strip-Wells  /  $440 +1 FREE 8GB USB
96-Strip-Wells  /  $640 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,895 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,415 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM), ELISA Kit

 Also Known As   

Sheep Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) ELISA Kit

 Product Gene Name   

ACADM elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    607008
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 Species Reactivity    Sheep
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ACADM elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ACADM purchase    MBS7251347 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ACADM. The ELISA analytical biochemical technique of the MBS7251347 kit is based on ACADM antibody-ACADM antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ACADM antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ACADM. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ACADM. It may not necessarily be applicable to this product.
 NCBI GI #    187960098
 NCBI GeneID    34
 NCBI Accession #    NP_001120800.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001127328.2 [Other Products]
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 UniProt Secondary Accession #    Q5T4U4; Q9NYF1 [Other Products]
 UniProt Related Accession #    P11310 [Other Products]
 Molecular Weight    47,020 Da
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 NCBI Official Full Name    medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform b
 NCBI Official Synonym Full Names    acyl-CoA dehydrogenase, C-4 to C-12 straight chain
 NCBI Official Symbol    ACADM [Similar Products]
 NCBI Official Synonym Symbols   
MCAD; ACAD1; MCADH
[Similar Products]
 NCBI Protein Information    medium-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain
 UniProt Protein Name    Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
 Protein Family    Medium-chain specific acyl-CoA dehydrogenase
 UniProt Gene Name    ACADM [Similar Products]
 UniProt Synonym Gene Names    MCAD [Similar Products]
 UniProt Entry Name    ACADM_HUMAN
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 NCBI Summary for ACADM    This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ACADM    ACADM: This enzyme is specific for acyl chain lengths of 4 to 16. Defects in ACADM are the cause of acyl-CoA dehydrogenase medium-chain deficiency (ACADMD). It is an autosomal recessive disease which causes fasting hypoglycemia, hepatic dysfunction, and encephalopathy, often resulting in death in infancy. Belongs to the acyl-CoA dehydrogenase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - propanoate; Lipid Metabolism - fatty acid; Amino Acid Metabolism - valine, leucine and isoleucine degradation; EC 1.3.8.7; Mitochondrial; Other Amino Acids Metabolism - beta-alanine; Oxidoreductase

Chromosomal Location of Human Ortholog: 1p31

Cellular Component: mitochondrion; axon; mitochondrial matrix; nucleus

Molecular Function: identical protein binding; acyl-CoA dehydrogenase activity; FAD binding

Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation; medium-chain fatty acid catabolic process; cellular lipid metabolic process; medium-chain fatty acid metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; carnitine biosynthetic process

Disease: Acyl-coa Dehydrogenase, Medium-chain, Deficiency Of
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 Research Articles on ACADM    1. Identify an ACADM founder mutation for MCADD in Saudi Arabian population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ACADM elisa kitPathways associated with ACADM elisa kit
 Reference Product  PubMed Publications
 ACADL elisa kit  >5 publications with ACADM and ACADL
 CPT1A elisa kit  >3 publications with ACADM and CPT1A
 EHHADH elisa kit  >1 publications with ACADM and EHHADH
 ACAA2 elisa kit  >1 publications with ACADM and ACAA2
 Products by Pathway  Pathway Diagram
 Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway antibodies  Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway Diagram
 Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway antibodies  Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
Diseases associated with ACADM elisa kitOrgans/Tissues associated with ACADM elisa kit
 Disease Name  Pubmed Publications
 Medium chain acyl CoA dehydrogenase deficiency Antibodies  >20 publications with ACADM and Medium chain acyl CoA dehydrogenase deficiency
 Fatty Liver Antibodies  >9 publications with ACADM and Fatty Liver
 Cardiovascular Diseases Antibodies  >4 publications with ACADM and Cardiovascular Diseases
 Obesity Antibodies  >4 publications with ACADM and Obesity
 Liver Diseases Antibodies  >3 publications with ACADM and Liver Diseases
 Heart Diseases Antibodies  >3 publications with ACADM and Heart Diseases
 Insulin Resistance Antibodies  >2 publications with ACADM and Insulin Resistance
 Disease Models, Animal Antibodies  >2 publications with ACADM and Disease Models, Animal
 Fibrosis Antibodies  >1 publications with ACADM and Fibrosis
 Hepatomegaly Antibodies  >1 publications with ACADM and Hepatomegaly
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with ACADM and Blood
 Liver Antibodies  >9 publications with ACADM and Liver
 Heart Antibodies  >5 publications with ACADM and Heart
 Adipose Tissue Antibodies  >4 publications with ACADM and Adipose Tissue
 Connective Tissue Antibodies  >3 publications with ACADM and Connective Tissue
 Muscle Antibodies  >3 publications with ACADM and Muscle
 Kidney Antibodies  >3 publications with ACADM and Kidney
 Thyroid Antibodies  >2 publications with ACADM and Thyroid
 Vascular Antibodies  >2 publications with ACADM and Vascular
 Pancreas Antibodies  >2 publications with ACADM and Pancreas
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