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NUP214 elisa kit :: Sheep Nucleoporin 214Kda ELISA Kit

Scan QR to view Datasheet Catalog #    MBS007064 NUP214 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nucleoporin 214Kda (NUP214), ELISA Kit

 Also Known As   

Sheep Nucleoporin 214Kda ELISA Kit

 Product Gene Name   

NUP214 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    114350
 3D Structure    ModBase 3D Structure for P35658
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 Species Reactivity    Sheep
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NUP214 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NUP214 purchase    MBS007064 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Nucleoporin 214Kda (NUP214) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NUP214. The ELISA analytical biochemical technique of the MBS007064 kit is based on NUP214 antibody-NUP214 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NUP214 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NUP214. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for NUP214. It may not necessarily be applicable to this product.
 NCBI GI #    33946327
 NCBI GeneID    8021
 NCBI Accession #    NP_005076.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_005085.3 [Other Products]
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 UniProt Primary Accession #    P35658 [Other Products]
 UniProt Secondary Accession #    Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3; A6NFQ0 [Other Products]
 UniProt Related Accession #    P35658 [Other Products]
 Molecular Weight    213,620 Da
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 NCBI Official Full Name    nuclear pore complex protein Nup214
 NCBI Official Synonym Full Names    nucleoporin 214kDa
 NCBI Official Symbol    NUP214 [Similar Products]
 NCBI Official Synonym Symbols   
CAN; CAIN; N214; p250; D9S46E
[Similar Products]
 NCBI Protein Information    nuclear pore complex protein Nup214; CAN protein, putative oncogene
 UniProt Protein Name    Nuclear pore complex protein Nup214
 UniProt Synonym Protein Names   
214 kDa nucleoporin; Nucleoporin Nup214; Protein CAN
 Protein Family    Nuclear pore complex protein
 UniProt Gene Name    NUP214 [Similar Products]
 UniProt Synonym Gene Names    CAIN; CAN; KIAA0023 [Similar Products]
 UniProt Entry Name    NU214_HUMAN
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 NCBI Summary for NUP214    The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NUP214    NUP214: May serve as a docking site in the receptor-mediated import of substrates across the nuclear pore complex. A chromosomal aberration involving NUP214 is found in a subset of acute myeloid leukemia (AML); also known as acute non-lymphocytic leukemia. Translocation t(6;9)(p23;q34) with DEK. It results in the formation of a DEK-CAN fusion gene. A chromosomal aberration involving NUP214 is found in some cases of acute undifferentiated leukemia (AUL). Translocation t(6;9)(q21;q34.1) with SET. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Oncoprotein; Nuclear export; Nucleoporin

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: nucleoplasm; focal adhesion; intracellular membrane-bound organelle; nuclear pore; cytosol; nucleus

Molecular Function: protein binding; transporter activity; nucleocytoplasmic transporter activity

Biological Process: viral reproduction; regulation of cell cycle; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; mRNA export from nucleus; protein import into nucleus; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; protein export from nucleus; transmembrane transport

Disease: Leukemia, Acute Lymphoblastic
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 Research Articles on NUP214    1. NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NUP214 elisa kitPathways associated with NUP214 elisa kit
 Reference Product  PubMed Publications
 NUP153 elisa kit  >31 publications with NUP214 and NUP153
 NUP88 elisa kit  >19 publications with NUP214 and NUP88
 NUP62 elisa kit  >11 publications with NUP214 and NUP62
 NXF1 elisa kit  >4 publications with NUP214 and NXF1
 DDX19B elisa kit  >3 publications with NUP214 and DDX19B
 NUP107 elisa kit  >3 publications with NUP214 and NUP107
 NUP133 elisa kit  >2 publications with NUP214 and NUP133
 XPO1 elisa kit  >2 publications with NUP214 and XPO1
 SMAD2 elisa kit  >1 publications with NUP214 and SMAD2
 Products by Pathway  Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 BMP Receptor Signaling Pathway antibodies  BMP Receptor Signaling Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Export Of Viral Ribonucleoproteins From Nucleus Pathway antibodies  Export Of Viral Ribonucleoproteins From Nucleus Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
Diseases associated with NUP214 elisa kitOrgans/Tissues associated with NUP214 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >81 publications with NUP214 and Neoplasms
 Leukemia, Myeloid, Acute Antibodies  >32 publications with NUP214 and Leukemia, Myeloid, Acute
 Cell Transformation, Neoplastic Antibodies  >9 publications with NUP214 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >3 publications with NUP214 and Neoplasms, Experimental
 Death Antibodies  >3 publications with NUP214 and Death
 Disease Models, Animal Antibodies  >3 publications with NUP214 and Disease Models, Animal
 Anemia Antibodies  >2 publications with NUP214 and Anemia
 Weight Loss Antibodies  >1 publications with NUP214 and Weight Loss
 Hyperplasia Antibodies  >1 publications with NUP214 and Hyperplasia
 Liver Neoplasms, Experimental Antibodies  >1 publications with NUP214 and Liver Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >15 publications with NUP214 and Blood
 Bone Antibodies  >11 publications with NUP214 and Bone
 Bone Marrow Antibodies  >9 publications with NUP214 and Bone Marrow
 Liver Antibodies  >5 publications with NUP214 and Liver
 Kidney Antibodies  >3 publications with NUP214 and Kidney
 Lung Antibodies  >2 publications with NUP214 and Lung
 Stomach Antibodies  >2 publications with NUP214 and Stomach
 Muscle Antibodies  >1 publications with NUP214 and Muscle
 Lymph Node Antibodies  >1 publications with NUP214 and Lymph Node
 Embryonic Tissue Antibodies  >1 publications with NUP214 and Embryonic Tissue
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