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PCII elisa kit :: Sheep Procollagen II ELISA Kit

Scan QR to view Datasheet Catalog #    MBS083854 PCII elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Procollagen II (PCII), ELISA Kit

 Also Known As   

Sheep Procollagen II ELISA Kit

 Product Gene Name   

PCII elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P05539
 Species Reactivity    Sheep
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PCII elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PCII purchase    MBS083854 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Procollagen II (PCII) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PCII. The ELISA analytical biochemical technique of the MBS083854 kit is based on PCII antibody-PCII antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PCII antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PCII. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PCII. It may not necessarily be applicable to this product.
 NCBI GI #    149032179
 NCBI GeneID    25412
 NCBI Accession #    EDL87091.1 [Other Products]
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 UniProt Primary Accession #    P05539 [Other Products]
 UniProt Secondary Accession #    Q63123; Q63565; Q78DY3 [Other Products]
 UniProt Related Accession #    P05539 [Other Products]
 Molecular Weight    134,570 Da
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 NCBI Official Full Name    procollagen, type II, alpha 1, isoform CRA_c
 NCBI Official Synonym Full Names    collagen, type II, alpha 1
 NCBI Official Symbol    Col2a1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    collagen alpha-1(II) chain; collagen alpha-1(II) chain; Procollagen II alpha 1; alpha-1 type II collagen; procollagen, type II, alpha 1; collagen type II (Col2A1) gene, enhancer region
 UniProt Protein Name    Collagen alpha-1(II) chain
 UniProt Synonym Protein Names   
Alpha-1 type II collagen
 UniProt Gene Name    Col2a1 [Similar Products]
 UniProt Entry Name    CO2A1_RAT
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 NCBI Summary for PCII    structural component of the cartilage extracellular matrix [RGD, Feb 2006]
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 UniProt Comments for PCII    Function: Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.

Subunit structure: Homotrimers of alpha 1(II) chains.

Subcellular location: Secreted › extracellular space › extracellular matrix

By similarity.

Tissue specificity: Expressed in chondrocytes. Ref.5

Domain: The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function

By similarity.

Post-translational modification: Prolines at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Probably 3-hydroxylated on Pro-602, Pro-839, Pro-1076, Pro-1133, Pro-1139 and Pro-1145 by LEPREL1.

Sequence similarities: Belongs to the fibrillar collagen family.Contains 1 fibrillar collagen NC1 domain.
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 Research Articles on PCII    1. Screening of the Col2a1 gene, and enhancer domain, for the sequence encoded regulation of its expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PCII elisa kitDiseases associated with PCII elisa kit
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway antibodies  Assembly Of Collagen Fibrils And Other Multimeric Structures Pathway Diagram
 Collagen Biosynthesis And Modifying Enzymes Pathway antibodies  Collagen Biosynthesis And Modifying Enzymes Pathway Diagram
 Collagen Formation Pathway antibodies  Collagen Formation Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Disease Name  Pubmed Publications
 Osteoarthritis Antibodies  >223 publications with PCII and Osteoarthritis
 Osteochondrodysplasias Antibodies  >140 publications with PCII and Osteochondrodysplasias
 Retinal Detachment Antibodies  >52 publications with PCII and Retinal Detachment
 Myopia Antibodies  >43 publications with PCII and Myopia
 Cleft Palate Antibodies  >40 publications with PCII and Cleft Palate
 Craniofacial Abnormalities Antibodies  >37 publications with PCII and Craniofacial Abnormalities
 Necrosis Antibodies  >34 publications with PCII and Necrosis
 Neoplasms Antibodies  >31 publications with PCII and Neoplasms
 Kniest dysplasia Antibodies  >25 publications with PCII and Kniest dysplasia
 Hearing Loss, Sensorineural Antibodies  >23 publications with PCII and Hearing Loss, Sensorineural
Organs/Tissues associated with PCII elisa kit
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >276 publications with PCII and Connective Tissue
 Embryonic Tissue Antibodies  >97 publications with PCII and Embryonic Tissue
 Brain Antibodies  >18 publications with PCII and Brain
 Kidney Antibodies  >15 publications with PCII and Kidney
 Heart Antibodies  >10 publications with PCII and Heart
 Inner Ear Antibodies  >8 publications with PCII and Inner Ear
 Lung Antibodies  >5 publications with PCII and Lung
 Uncharacterized Tissue Antibodies  >4 publications with PCII and Uncharacterized Tissue
 Spleen Antibodies  >1 publications with PCII and Spleen
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