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SEMA7A elisa kit :: Sheep Semaphorin 7A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS018348 SEMA7A elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Semaphorin 7A (SEMA7A), ELISA Kit

 Also Known As   

Sheep Semaphorin 7A ELISA Kit

 Product Gene Name   

SEMA7A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 15; NC_000015.9 (74701630..74726299, complement). Location: 15q22.3-q23
 OMIM    607961
 3D Structure    ModBase 3D Structure for O75326
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 Species Reactivity    Sheep
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SEMA7A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SEMA7A purchase    MBS018348 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Semaphorin 7A (SEMA7A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SEMA7A. The ELISA analytical biochemical technique of the MBS018348 kit is based on SEMA7A antibody-SEMA7A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SEMA7A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SEMA7A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SEMA7A. It may not necessarily be applicable to this product.
 NCBI GI #    225637520
 NCBI GeneID    8482
 NCBI Accession #    NP_001139501.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001146029.1 [Other Products]
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 UniProt Primary Accession #    O75326 [Other Products]
 UniProt Secondary Accession #    Q1XE81; Q1XE82; Q1XE83; Q1XE84; Q3MIY5; B4DDP7; F5H1S0 [Other Products]
 UniProt Related Accession #    O75326 [Other Products]
 Molecular Weight    74,824 Da
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 NCBI Official Full Name    semaphorin-7A isoform 2 preproprotein
 NCBI Official Synonym Full Names    semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
 NCBI Official Symbol    SEMA7A [Similar Products]
 NCBI Official Synonym Symbols   
JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1
[Similar Products]
 NCBI Protein Information    semaphorin-7A; sema L; sema K1; semaphorin L; semaphorin-L; semaphorin K1; semaphorin-K1; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group)
 UniProt Protein Name    Semaphorin-7A
 UniProt Synonym Protein Names   
CDw108; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L
 Protein Family    Semaphorin
 UniProt Gene Name    SEMA7A [Similar Products]
 UniProt Synonym Gene Names    CD108; SEMAL; Sema K1; Sema L [Similar Products]
 UniProt Entry Name    SEM7A_HUMAN
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 NCBI Summary for SEMA7A    The protein encoded by this gene binds to cell surfaces through a glycosylphosphatidylinositol (GPI) linkage. The encoded glycoprotein is found on activated lymphocytes and erythrocytes. This protein may be involved in immunomodulatory and neuronal processes. Defects in this gene can result in loss of bone mineral density (BMD). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
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 UniProt Comments for SEMA7A    SEMA7A: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. Belongs to the semaphorin family.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 15q22.3-q23

Cellular Component: membrane; plasma membrane; external side of plasma membrane

Molecular Function: integrin binding; protein binding; receptor activity

Biological Process: osteoblast differentiation; integrin-mediated signaling pathway; axon guidance; axon extension; positive regulation of axon extension; regulation of inflammatory response; olfactory lobe development; immune response; positive regulation of protein amino acid phosphorylation; inflammatory response

Disease: Blood Group, John Milton Hagen System
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 Research Articles on SEMA7A    1. two MTRAP monomers interact via their tandem TSR domains with the Sema domains of a Semaphorin-7A homodimer
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with SEMA7A elisa kitDiseases associated with SEMA7A elisa kit
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Other Semaphorin Interactions Pathway antibodies  Other Semaphorin Interactions Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >8 publications with SEMA7A and Inflammation
 Immune System Diseases Antibodies  >4 publications with SEMA7A and Immune System Diseases
 Nervous System Diseases Antibodies  >4 publications with SEMA7A and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with SEMA7A and Brain Diseases
 Neoplasms Antibodies  >3 publications with SEMA7A and Neoplasms
 Cardiovascular Diseases Antibodies  >2 publications with SEMA7A and Cardiovascular Diseases
 Drug Toxicity Antibodies  >2 publications with SEMA7A and Drug Toxicity
 Weight Loss Antibodies  >1 publications with SEMA7A and Weight Loss
 Skin Neoplasms Antibodies  >1 publications with SEMA7A and Skin Neoplasms
 Necrosis Antibodies  >1 publications with SEMA7A and Necrosis
Organs/Tissues associated with SEMA7A elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >23 publications with SEMA7A and Blood
 Brain Antibodies  >14 publications with SEMA7A and Brain
 Embryonic Tissue Antibodies  >8 publications with SEMA7A and Embryonic Tissue
 Bone Antibodies  >7 publications with SEMA7A and Bone
 Skin Antibodies  >6 publications with SEMA7A and Skin
 Spleen Antibodies  >5 publications with SEMA7A and Spleen
 Lung Antibodies  >5 publications with SEMA7A and Lung
 Thymus Antibodies  >4 publications with SEMA7A and Thymus
 Testis Antibodies  >3 publications with SEMA7A and Testis
 Bone Marrow Antibodies  >3 publications with SEMA7A and Bone Marrow
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