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SSH3 elisa kit :: Sheep Slingshot Homolog 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS095463 SSH3 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Slingshot Homolog 3 (SSH3), ELISA Kit

 Also Known As   

Sheep Slingshot Homolog 3 ELISA Kit

 Product Gene Name   

SSH3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    606780
 3D Structure    ModBase 3D Structure for Q8TE77
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 Species Reactivity    Sheep
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SSH3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SSH3 purchase    MBS095463 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Slingshot Homolog 3 (SSH3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SSH3. The ELISA analytical biochemical technique of the MBS095463 kit is based on SSH3 antibody-SSH3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SSH3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SSH3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SSH3. It may not necessarily be applicable to this product.
 NCBI GI #    119594999
 NCBI GeneID    54961
 NCBI Accession #    EAW74593.1 [Other Products]
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 UniProt Primary Accession #    Q8TE77 [Other Products]
 UniProt Secondary Accession #    Q6PK42; Q76I75; Q8N9L8; Q8WYL0; Q9NV45; Q9NWZ7 [Other Products]
 UniProt Related Accession #    Q8TE77 [Other Products]
 Molecular Weight    72,996 Da
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 NCBI Official Full Name    slingshot homolog 3 (Drosophila), isoform CRA_g
 NCBI Official Synonym Full Names    slingshot protein phosphatase 3
 NCBI Official Symbol    SSH3 [Similar Products]
 NCBI Official Synonym Symbols   
SSH3L
[Similar Products]
 NCBI Protein Information    protein phosphatase Slingshot homolog 3; SSH-3L; hSSH-3L; slingshot 3; SSH-like protein 3; slingshot homolog 3
 UniProt Protein Name    Protein phosphatase Slingshot homolog 3
 UniProt Synonym Protein Names   
SSH-like protein 3
 Protein Family    Protein phosphatase Slingshot
 UniProt Gene Name    SSH3 [Similar Products]
 UniProt Synonym Gene Names    SSH3L; SSH-3L; hSSH-3L [Similar Products]
 UniProt Entry Name    SSH3_HUMAN
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 NCBI Summary for SSH3    The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for SSH3    SSH3: a protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Does not bind to, or colocalize with, filamentous actin. Five alternatively spliced isoforms have been described.

Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Cytoskeletal; Protein phosphatase, dual-specificity; EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor); Phosphatase

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cytoskeleton; cytoplasm; nucleus

Molecular Function: DNA binding; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; actin binding

Biological Process: regulation of actin polymerization and/or depolymerization; regulation of axonogenesis; protein amino acid dephosphorylation
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 Research Articles on SSH3    1. Expression of phosphatase-dead versions of SSH proteins, SSH1, SSH2 & SSH3 results in phosphorylation/inactivation of cofilin, changes in cytoskeleton organization, loss of cell polarity, and assembly of aberrant arrays of laminin-332 in keratinocytes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SSH3 elisa kitPathways associated with SSH3 elisa kit
 Reference Product  PubMed Publications
 LIMK1 elisa kit  >1 publications with SSH3 and LIMK1
 Products by Pathway  Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
 Regulation Of Actin Cytoskeleton Pathway antibodies  Regulation Of Actin Cytoskeleton Pathway Diagram
Diseases associated with SSH3 elisa kitOrgans/Tissues associated with SSH3 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >1 publications with SSH3 and Kidney Diseases
 Head and Neck Neoplasms Antibodies  >1 publications with SSH3 and Head and Neck Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with SSH3 and Neoplasms, Experimental
 Neoplasms Antibodies  >1 publications with SSH3 and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >1 publications with SSH3 and Thyroid
 Muscle Antibodies  >1 publications with SSH3 and Muscle
 Lung Antibodies  >1 publications with SSH3 and Lung
 Kidney Antibodies  >1 publications with SSH3 and Kidney
 Brain Antibodies  >1 publications with SSH3 and Brain
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