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SDF1 elisa kit :: Sheep Stromal Cell Derived Factor 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS034888 SDF1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Stromal Cell Derived Factor 1 (SDF1), ELISA Kit

★Popular Item★
 Also Known As   

Sheep Stromal Cell Derived Factor 1 ELISA Kit

 Product Gene Name   

SDF1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 10; NC_000010.10 (44865605..44880545, complement). Location: 10q11.1
 OMIM    600835
 3D Structure    ModBase 3D Structure for P48061
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 Species Reactivity    Sheep
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.25 ng/ml - 8 ng/mL
 Sensitivity    0.1 ng/mL
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SDF1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SDF1 purchase    MBS034888 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Stromal Cell Derived Factor 1 (SDF1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 ng/ml - 8 ng/mL in biological research samples containing SDF1, with an estimated sensitivity of 0.1 ng/mL. The ELISA analytical biochemical technique of the MBS034888 kit is based on SDF1 antibody-SDF1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SDF1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SDF1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SDF1 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SDF1 (hereafter termed "analyte") in undiluted original Sheep body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS034888. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SDF1. It may not necessarily be applicable to this product.
 NCBI GI #    489406390
 NCBI GeneID    6387
 NCBI Accession #    NP_001264919.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001277990.1 [Other Products]
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 UniProt Primary Accession #    P48061 [Other Products]
 UniProt Secondary Accession #    Q2L985; Q2L986; Q2L988; Q5IT36; Q6ICW0; Q9H554; B2R4G0; E7EVL0 [Other Products]
 UniProt Related Accession #    P48061 [Other Products]
 Molecular Weight    10,666 Da
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 NCBI Official Full Name    stromal cell-derived factor 1 isoform 5
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) ligand 12
 NCBI Official Symbol    CXCL12 [Similar Products]
 NCBI Official Synonym Symbols   
IRH; PBSF; SDF1; TLSF; TPAR1; SCYB12
[Similar Products]
 NCBI Protein Information    stromal cell-derived factor 1; intercrine reduced in hepatomas; pre-B cell growth-stimulating factor
 UniProt Protein Name    Stromal cell-derived factor 1
 UniProt Synonym Protein Names   
C-X-C motif chemokine 12; Intercrine reduced in hepatomas; IRH; hIRH; Pre-B cell growth-stimulating factor
 UniProt Gene Name    CXCL12 [Similar Products]
 UniProt Synonym Gene Names    SDF1; SDF1A; SDF1B; SDF-1; hSDF-1; IRH; hIRH; PBSF [Similar Products]
 UniProt Entry Name    SDF1_HUMAN
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 NCBI Summary for SDF1    This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
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 UniProt Comments for SDF1    CXCL12: Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to another C-X-C chemokine receptor CXCR7, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1- alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3- 67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and CXCR7, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. Inhibits CXCR4-mediated infection by T- cell line-adapted HIV-1. Plays a protective role after myocardial infarction. Induces down-regulation and internalization of CXCR7 expressed in various cells. Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Monomer or homodimer; in equilibrium. Dimer formation is induced by non acidic pH and the presence of multivalent anions, and by binding to CXCR4 or heparin. Monomeric form is required for full chemotactic activity and resistance to ischemia/reperfusion injury, whereas the dimeric form acts as a partial agonist of CXCR4, stimulating Ca2+ mobilization but with no chemotactic activity and instead acts as a selective antagonist that blocks chemotaxis induced by the monomeric form. Interacts with the N- terminus of CXCR7. Isoform Alpha and isoform Beta are ubiquitously expressed, with highest levels detected in liver, pancreas and spleen. Isoform Gamma is mainly expressed in heart, with weak expression detected in several other tissues. Isoform Delta, isoform Epsilon and isoform Theta have highest expression levels in pancreas, with lower levels detected in heart, kidney, liver and spleen. Belongs to the intercrine alpha (chemokine CxC) family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Chemokine; Secreted; Cell development/differentiation; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q11.1

Cellular Component: extracellular space; extracellular region; external side of plasma membrane

Molecular Function: growth factor activity; chemokine receptor binding; chemokine activity; CXCR chemokine receptor binding; receptor binding

Biological Process: response to peptide hormone stimulus; positive regulation of dopamine secretion; positive regulation of cell adhesion; blood circulation; adult locomotory behavior; neuron migration; motor axon guidance; chemotaxis; signal transduction; germ cell development; induction of positive chemotaxis; T cell proliferation; response to radiation; germ cell migration; cell adhesion; organ regeneration; response to virus; regulation of actin polymerization and/or depolymerization; cellular calcium ion homeostasis; patterning of blood vessels; G-protein coupled receptor protein signaling pathway; response to heat; response to mechanical stimulus; ameboidal cell migration; response to hypoxia; positive regulation of axon extension involved in axon guidance; immune response; positive regulation of endothelial cell proliferation; telencephalon cell migration

Disease: Human Immunodeficiency Virus Type 1, Susceptibility To
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 Research Articles on SDF1    1. our results suggest that high endothelial venules development and engagement of SDF-1 contribute to myasthenia gravis (MG) pathology by recruitment of peripheral B cells and APCs to the MG thymus.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SDF1 elisa kitPathways associated with SDF1 elisa kit
 Reference Product  PubMed Publications
 CXCR4 elisa kit  >2839 publications with SDF1 and CXCR4
 CCR5 elisa kit  >277 publications with SDF1 and CCR5
 CXCR7 elisa kit  >188 publications with SDF1 and CXCR7
 CXCR3 elisa kit  >112 publications with SDF1 and CXCR3
 HIF1A elisa kit  >67 publications with SDF1 and HIF1A
 CCR4 elisa kit  >40 publications with SDF1 and CCR4
 STAT3 elisa kit  >30 publications with SDF1 and STAT3
 JAK2 elisa kit  >15 publications with SDF1 and JAK2
 VAV1 elisa kit  >14 publications with SDF1 and VAV1
 SDC4 elisa kit  >5 publications with SDF1 and SDC4
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
Diseases associated with SDF1 elisa kitOrgans/Tissues associated with SDF1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1281 publications with SDF1 and Neoplasms
 Cardiovascular Diseases Antibodies  >477 publications with SDF1 and Cardiovascular Diseases
 Inflammation Antibodies  >459 publications with SDF1 and Inflammation
 Neoplasm Metastasis Antibodies  >322 publications with SDF1 and Neoplasm Metastasis
 HIV Infections Antibodies  >256 publications with SDF1 and HIV Infections
 Breast Neoplasms Antibodies  >230 publications with SDF1 and Breast Neoplasms
 Heart Diseases Antibodies  >222 publications with SDF1 and Heart Diseases
 Neoplasm Invasiveness Antibodies  >185 publications with SDF1 and Neoplasm Invasiveness
 Necrosis Antibodies  >183 publications with SDF1 and Necrosis
 Myocardial Infarction Antibodies  >172 publications with SDF1 and Myocardial Infarction
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >1258 publications with SDF1 and Bone
 Bone Marrow Antibodies  >1163 publications with SDF1 and Bone Marrow
 Vascular Antibodies  >927 publications with SDF1 and Vascular
 Brain Antibodies  >411 publications with SDF1 and Brain
 Muscle Antibodies  >309 publications with SDF1 and Muscle
 Lung Antibodies  >269 publications with SDF1 and Lung
 Heart Antibodies  >247 publications with SDF1 and Heart
 Liver Antibodies  >227 publications with SDF1 and Liver
 Embryonic Tissue Antibodies  >186 publications with SDF1 and Embryonic Tissue
 Nerve Antibodies  >150 publications with SDF1 and Nerve
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