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TGFR elisa kit :: Sheep Transforming Growth Factor Receptor ELISA Kit

Scan QR to view Datasheet Catalog #    MBS022509 TGFR elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Transforming Growth Factor Receptor (TGFR), ELISA Kit

 Also Known As   

Sheep Transforming Growth Factor Receptor ELISA Kit

 Product Gene Name   

TGFR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600742
 3D Structure    ModBase 3D Structure for Q03167
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 Species Reactivity    Sheep
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TGFR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TGFR purchase    MBS022509 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Transforming Growth Factor Receptor (TGFR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TGFR. The ELISA analytical biochemical technique of the MBS022509 kit is based on TGFR antibody-TGFR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TGFR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TGFR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for TGFR. It may not necessarily be applicable to this product.
 NCBI GI #    307574634
 NCBI GeneID    7049
 NCBI Accession #    NP_001182613.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001195684.1 [Other Products]
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 UniProt Primary Accession #    Q03167 [Other Products]
 UniProt Secondary Accession #    Q5T2T4; Q5U731; Q9UGI2; A0AUW8; A8K5N0; B9EG88 [Other Products]
 UniProt Related Accession #    Q03167 [Other Products]
 Molecular Weight    93,499 Da
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 NCBI Official Full Name    transforming growth factor beta receptor type 3 isoform b
 NCBI Official Synonym Full Names    transforming growth factor, beta receptor III
 NCBI Official Symbol    TGFBR3 [Similar Products]
 NCBI Official Synonym Symbols   
BGCAN; betaglycan
[Similar Products]
 NCBI Protein Information    transforming growth factor beta receptor type 3; TGFR-3; betaglycan proteoglycan; TGF-beta receptor type 3; TGF-beta receptor type III
 UniProt Protein Name    Transforming growth factor beta receptor type 3
 UniProt Synonym Protein Names   
Betaglycan; Transforming growth factor beta receptor III
 UniProt Gene Name    TGFBR3 [Similar Products]
 UniProt Synonym Gene Names    TGF-beta receptor type 3; TGFR-3 [Similar Products]
 UniProt Entry Name    TGBR3_HUMAN
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 NCBI Summary for TGFR    This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]
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 UniProt Comments for TGFR    TGFBR3: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Interacts with TCTEX1D4. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p33-p32

Cellular Component: extracellular space; proteinaceous extracellular matrix; cell surface; integral to plasma membrane; endoplasmic reticulum; receptor complex; external side of plasma membrane

Molecular Function: transforming growth factor beta receptor activity; heparin binding; protein binding; fibroblast growth factor binding; glycosaminoglycan binding; transforming growth factor beta binding; punt binding; activin binding; coreceptor activity; SMAD binding; transforming growth factor beta receptor binding; PDZ domain binding

Biological Process: heart morphogenesis; transforming growth factor beta receptor complex assembly; blood vessel development; cell migration; organ regeneration; blastocyst development; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of cell motility; cardiac muscle cell proliferation; palate development; liver development; activation of NF-kappaB transcription factor; BMP signaling pathway; transforming growth factor beta receptor signaling pathway; regulation of protein binding; response to hypoxia; epithelial to mesenchymal transition; ventricular cardiac muscle morphogenesis; immune response; cell growth; negative regulation of transforming growth factor beta receptor signaling pathway; response to follicle-stimulating hormone stimulus; negative regulation of epithelial cell proliferation
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 Research Articles on TGFR    1. Low TGFBR3 expression is associated with bladder urothelial carcinoma and enhanced in the invasive bladder cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TGFR elisa kitPathways associated with TGFR elisa kit
 Reference Product  PubMed Publications
 TGFB1 elisa kit  >94 publications with TGFR and TGFB1
 TGFB2 elisa kit  >51 publications with TGFR and TGFB2
 TGFBR1 elisa kit  >15 publications with TGFR and TGFBR1
 TGFBR2 elisa kit  >13 publications with TGFR and TGFBR2
 CTGF elisa kit  >5 publications with TGFR and CTGF
 BAMBI elisa kit  >3 publications with TGFR and BAMBI
 INHA elisa kit  >3 publications with TGFR and INHA
 ACVR2A elisa kit  >1 publications with TGFR and ACVR2A
 Products by Pathway  Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
Diseases associated with TGFR elisa kitOrgans/Tissues associated with TGFR elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >107 publications with TGFR and Neoplasms
 Fibrosis Antibodies  >24 publications with TGFR and Fibrosis
 Disease Models, Animal Antibodies  >23 publications with TGFR and Disease Models, Animal
 Inflammation Antibodies  >21 publications with TGFR and Inflammation
 Breast Neoplasms Antibodies  >18 publications with TGFR and Breast Neoplasms
 Lung Neoplasms Antibodies  >13 publications with TGFR and Lung Neoplasms
 Ovarian Neoplasms Antibodies  >11 publications with TGFR and Ovarian Neoplasms
 Nervous System Diseases Antibodies  >10 publications with TGFR and Nervous System Diseases
 Liver Diseases Antibodies  >9 publications with TGFR and Liver Diseases
 Heart Diseases Antibodies  >9 publications with TGFR and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >33 publications with TGFR and Ovary
 Brain Antibodies  >31 publications with TGFR and Brain
 Connective Tissue Antibodies  >25 publications with TGFR and Connective Tissue
 Kidney Antibodies  >18 publications with TGFR and Kidney
 Liver Antibodies  >17 publications with TGFR and Liver
 Testis Antibodies  >16 publications with TGFR and Testis
 Skin Antibodies  >12 publications with TGFR and Skin
 Eye Antibodies  >11 publications with TGFR and Eye
 Placenta Antibodies  >9 publications with TGFR and Placenta
 Mouth Antibodies  >9 publications with TGFR and Mouth
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