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XRCC5 elisa kit :: Sheep X-Ray Repair Cross Complementing 5 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS068989 XRCC5 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

X-Ray Repair Cross Complementing 5 (XRCC5), ELISA Kit

 Also Known As   

Sheep X-Ray Repair Cross Complementing 5 ELISA Kit

 Product Gene Name   

XRCC5 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    152690
 3D Structure    ModBase 3D Structure for P12956
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 Species Reactivity    Sheep
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of XRCC5 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for XRCC5 purchase    MBS068989 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the X-Ray Repair Cross Complementing 5 (XRCC5) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing XRCC5. The ELISA analytical biochemical technique of the MBS068989 kit is based on XRCC5 antibody-XRCC5 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect XRCC5 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, XRCC5. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for XRCC5. It may not necessarily be applicable to this product.
 NCBI GI #    4503841
 NCBI GeneID    2547
 NCBI Accession #    NP_001460.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001469.4 [Other Products]
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 UniProt Primary Accession #    P12956 [Other Products]
 UniProt Secondary Accession #    Q6FG89; Q9UCQ2; Q9UCQ3 [Other Products]
 UniProt Related Accession #    P12956 [Other Products]
 Molecular Weight    69,843 Da
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 NCBI Official Full Name    X-ray repair cross-complementing protein 6 isoform 1
 NCBI Official Synonym Full Names    X-ray repair complementing defective repair in Chinese hamster cells 6
 NCBI Official Symbol    XRCC6 [Similar Products]
 NCBI Official Synonym Symbols   
ML8; KU70; TLAA; CTC75; CTCBF; G22P1
[Similar Products]
 NCBI Protein Information    X-ray repair cross-complementing protein 6; 5'-dRP lyase Ku70; Ku autoantigen, 70kDa; DNA repair protein XRCC6; Ku autoantigen p70 subunit; 70 kDa subunit of Ku antigen; thyroid-lupus autoantigen p70; lupus Ku autoantigen protein p70; 5'-deoxyribose-5-phosphate lyase Ku70; CTC box binding factor 75 kDa subunit; CTC box-binding factor 75 kDa subunit; thyroid autoantigen 70kD (Ku antigen); ATP-dependent DNA helicase 2 subunit 1; thyroid autoantigen 70kDa (Ku antigen); ATP-dependent DNA helicase II 70 kDa subunit; ATP-dependent DNA helicase II, 70 kDa subunit
 UniProt Protein Name    X-ray repair cross-complementing protein 6
 UniProt Synonym Protein Names   
5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6
 UniProt Gene Name    XRCC6 [Similar Products]
 UniProt Synonym Gene Names    G22P1; 5'-dRP lyase Ku70; CTC75; CTCBF; Ku70; TLAA [Similar Products]
 UniProt Entry Name    XRCC6_HUMAN
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 NCBI Summary for XRCC5    The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
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 UniProt Comments for XRCC5    Ku70: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. Allows DNA to undergo a single round of replication per cell cycle. Required for the entry in S phase and for cell division.

Protein type: Helicase; EC 3.6.4.-; DNA-binding; RNA-binding; Nuclear receptor co-regulator; EC 4.2.99.-; DNA repair, damage

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: nucleoplasm; transcription factor complex; nuclear telomere cap complex; membrane; nucleolus; nucleus; cytosol

Molecular Function: ATP-dependent DNA helicase activity; protein C-terminus binding; protein binding; DNA binding; double-stranded DNA binding; damaged DNA binding; double-stranded telomeric DNA binding; 5'-deoxyribose-5-phosphate lyase activity; ATP binding

Biological Process: positive regulation of neurogenesis; V(D)J recombination; viral reproduction; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; DNA repair; DNA duplex unwinding; double-strand break repair via nonhomologous end joining; DNA ligation; double-strand break repair; positive regulation of interferon type I production; innate immune response; positive regulation of transcription from RNA polymerase II promoter; brain development; negative regulation of transcription, DNA-dependent; telomere maintenance
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 Research Articles on XRCC5    1. SET/TAF-Ibeta interacts with Ku70/80 in the nucleus and inhibits Ku70 acetylation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with XRCC5 elisa kitPathways associated with XRCC5 elisa kit
 Reference Product  PubMed Publications
 XRCC5 elisa kit  >20 publications with XRCC5 and XRCC5
 XRCC4 elisa kit  >9 publications with XRCC5 and XRCC4
 LIG4 elisa kit  >4 publications with XRCC5 and LIG4
 PARP1 elisa kit  >3 publications with XRCC5 and PARP1
 PRKDC elisa kit  >3 publications with XRCC5 and PRKDC
 TP53 elisa kit  >1 publications with XRCC5 and TP53
 SIRT1 elisa kit  >1 publications with XRCC5 and SIRT1
 BAX elisa kit  >1 publications with XRCC5 and BAX
 WRN elisa kit  >1 publications with XRCC5 and WRN
 Products by Pathway  Pathway Diagram
 2-LTR Circle Formation Pathway antibodies  2-LTR Circle Formation Pathway Diagram
 BARD1 Signaling Events Pathway antibodies  BARD1 Signaling Events Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 Cytosolic Sensors Of Pathogen-associated DNA Pathway antibodies  Cytosolic Sensors Of Pathogen-associated DNA Pathway Diagram
 DNA Repair Pathway antibodies  DNA Repair Pathway Diagram
 DNA-PK Complex Pathway antibodies  DNA-PK Complex Pathway Diagram
 DNA-PK Complex Pathway antibodies  DNA-PK Complex Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Double-Strand Break Repair Pathway antibodies  Double-Strand Break Repair Pathway Diagram
 Early Phase Of HIV Life Cycle Pathway antibodies  Early Phase Of HIV Life Cycle Pathway Diagram
Diseases associated with XRCC5 elisa kitOrgans/Tissues associated with XRCC5 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >28 publications with XRCC5 and Neoplasms
 Carcinoma Antibodies  >12 publications with XRCC5 and Carcinoma
 Adenocarcinoma Antibodies  >9 publications with XRCC5 and Adenocarcinoma
 Breast Neoplasms Antibodies  >5 publications with XRCC5 and Breast Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with XRCC5 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >4 publications with XRCC5 and Liver Diseases
 Lymphoma Antibodies  >4 publications with XRCC5 and Lymphoma
 Liver Neoplasms Antibodies  >4 publications with XRCC5 and Liver Neoplasms
 Leukemia Antibodies  >3 publications with XRCC5 and Leukemia
 Chromosome Aberrations Antibodies  >3 publications with XRCC5 and Chromosome Aberrations
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >8 publications with XRCC5 and Blood
 Liver Antibodies  >5 publications with XRCC5 and Liver
 Lung Antibodies  >4 publications with XRCC5 and Lung
 Kidney Antibodies  >4 publications with XRCC5 and Kidney
 Brain Antibodies  >3 publications with XRCC5 and Brain
 Prostate Antibodies  >2 publications with XRCC5 and Prostate
 Bladder Antibodies  >2 publications with XRCC5 and Bladder
 Testis Antibodies  >2 publications with XRCC5 and Testis
 Heart Antibodies  >1 publications with XRCC5 and Heart
 Stomach Antibodies  >1 publications with XRCC5 and Stomach
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