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CPB1 enzyme :: Carboxypeptidase B Enzyme

Scan QR to view Datasheet Catalog #    MBS653983 CPB1 enzyme
Unit / Price
5 mg  /  $375 +1 FREE 8GB USB
10 mg  /  $525 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Carboxypeptidase B (CPB1), Enzyme

★Popular Item★
 Also Known As   

Carboxypeptidase B

 Product Gene Name   

CPB1 enzyme

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS653983 COA    COA PDF
 Chromosome Location    Chromosome: 3; NC_000003.11 (148508917..148577979). Location: 3q24
 OMIM    114852
 3D Structure    ModBase 3D Structure for P15086
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 Purity/Purification    Molecular Biology Grade
 Form/Format    Chromatographically purified and supplied as a solution in 0.1M sodium chloride.
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 Source    Porcine Pancreas
 CAS Number    9025-24-5
 Activity    247 u/mg protein
3090 u/ml
12.5 mg protein/ml
 Chymotrypsin    0.016%
 Carboxypeptidase A    0.28%
 Trypsin    0.005%
 Unit Definition    1 unit hydrolyzes 1 micromole of hippuryl-L-arginine per minute at 25C, pH 7.65
 Quality Control    SDS-PAGE
 Certificate of Origin    The raw animal product used in the manufacturing of Carboxypeptidase B is derived from materials originating in North America and collected in USDA approved facilities and inspected to be free of disease.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at - 20 degree C. Aliquots are stable for 6 months after receipt at -20 degree C. For maximum recovery or product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of CPB1 enzyme vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for CPB1 enzyme

   Carboxypeptidase B (CPB) catalyzes hydrolysis of the basic amino acids, lysine, arginine, and ornithine from the C-teminal position in polypeptides. It occurs as a zymogen in the pancreas of most vertebrates.
 Product Categories/Family for CPB1 enzyme    Molecular Biology; MB-Enzymes, Carboxypeptidase
NCBI/Uniprot data below describe general gene information for CPB1. It may not necessarily be applicable to this product.
 NCBI GI #    54607080
 NCBI GeneID    1360
 NCBI Accession #    NP_001862.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001871.2 [Other Products]
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 UniProt Primary Accession #    P15086 [Other Products]
 UniProt Secondary Accession #    O60834; Q53XJ0; Q96BQ8 [Other Products]
 UniProt Related Accession #    P15086 [Other Products]
 Molecular Weight    34.5kD [Similar Products]
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 NCBI Official Full Name    carboxypeptidase B preproprotein
 NCBI Official Synonym Full Names    carboxypeptidase B1 (tissue)
 NCBI Official Symbol    CPB1 [Similar Products]
 NCBI Official Synonym Symbols   
CPB; PASP; PCPB
[Similar Products]
 NCBI Protein Information    carboxypeptidase B; protaminase; procarboxypeptidase B; pancreas-specific protein; tissue carboxypeptidase B; pancreatic carboxypeptidase B
 UniProt Protein Name    Carboxypeptidase B
 UniProt Synonym Protein Names   
Pancreas-specific protein
 Protein Family    Carboxypeptidase
 UniProt Gene Name    CPB1 [Similar Products]
 UniProt Synonym Gene Names    CPB; PCPB; PASP [Similar Products]
 UniProt Entry Name    CBPB1_HUMAN
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 NCBI Summary for CPB1    Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CPB1    Catalytic activity: Preferential release of a C-terminal lysine or arginine amino acid.

Cofactor: Binds 1 zinc ion per subunit.

Subcellular location: Secreted.

Tissue specificity: Pancreas.

Sequence similarities: Belongs to the peptidase M14 family.
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 Research Articles on CPB1    1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CPB1 enzymePathways associated with CPB1 enzyme
 Reference Product  PubMed Publications
 CPE enzyme  >2 publications with CPB1 and CPE
 Products by Pathway  Pathway Diagram
 Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies  Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
 Protein Digestion And Absorption Pathway antibodies  Protein Digestion And Absorption Pathway Diagram
Diseases associated with CPB1 enzymeOrgans/Tissues associated with CPB1 enzyme
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with CPB1 and Neoplasms
 Prostatic Diseases Antibodies  >2 publications with CPB1 and Prostatic Diseases
 Inflammation Antibodies  >2 publications with CPB1 and Inflammation
 Carcinoma Antibodies  >1 publications with CPB1 and Carcinoma
 Kidney Diseases Antibodies  >1 publications with CPB1 and Kidney Diseases
 Liver Neoplasms Antibodies  >1 publications with CPB1 and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with CPB1 and Liver Diseases
 Liver Neoplasms, Experimental Antibodies  >1 publications with CPB1 and Liver Neoplasms, Experimental
 Hyperplasia Antibodies  >1 publications with CPB1 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >18 publications with CPB1 and Pancreas
 Prostate Antibodies  >2 publications with CPB1 and Prostate
 Spleen Antibodies  >2 publications with CPB1 and Spleen
 Adrenal Gland Antibodies  >1 publications with CPB1 and Adrenal Gland
 Heart Antibodies  >1 publications with CPB1 and Heart
 Liver Antibodies  >1 publications with CPB1 and Liver
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