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CRP human serum :: Serum Human Serum

Scan QR to view Datasheet Catalog #    MBS539649 CRP human serum
Unit / Price
100 mL  /  $1,010 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serum (CRP), Human Serum

 Also Known As   

Human Serum (CRP free)

 Product Synonym Names    CRP Free Human Plasma; C-Reactive Protein Free Serum
 Product Gene Name   

CRP human serum

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123260
 3D Structure    ModBase 3D Structure for P02741
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 Host    Human
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 Purity/Purification    Human Serum (CRP free) was purified by affinity chromatography.
 Form/Format    Frozen liquid. Contains less than 0.02 ug/ml of human CRP.
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 Source Note    Pooled normal Human serum
 Biological Significance    In blood, the serum is the component that is neither a blood cell (serum does not contain white or red blood cells) nor a clotting factor; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances (e.g., drugs and microorganisms).
 Biohazard Information    Donor samples were tested and found to be negative for HBsAg, HIV-1 and HIV-2 antibodies, and HCV. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
 Dry Ice Shipment    Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
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 Preparation and Storage    Aliquot and store at -20 degree C. Avoid repeated Freeze/Thaw cycles
 Other Notes    Small volumes of CRP human serum vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for CRP human serum

   C-reactive protein free normal human serum
 Product Categories/Family for CRP human serum    Serum, Plasma & Blood; Human Serum & Plasma
 Application Notes for CRP human serum    CRP free serum can be used for preparation of CRP standards and calibrators.
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NCBI/Uniprot data below describe general gene information for CRP. It may not necessarily be applicable to this product.
 NCBI GI #    30224
 NCBI GeneID    1401
 NCBI Accession #    CAA39671.1 [Other Products]
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 UniProt Primary Accession #    P02741 [Other Products]
 UniProt Secondary Accession #    Q08AK3; Q8WW75; A8K078; D3DVD9; D3DVE0 [Other Products]
 UniProt Related Accession #    P02741 [Other Products]
 Molecular Weight    10,415 Da [Similar Products]
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 NCBI Official Full Name    C-reactive protein
 NCBI Official Synonym Full Names    C-reactive protein, pentraxin-related
 NCBI Official Symbol    CRP [Similar Products]
 NCBI Official Synonym Symbols   
PTX1
[Similar Products]
 NCBI Protein Information    C-reactive protein
 UniProt Protein Name    C-reactive protein
 Protein Family    Serum albumin
 UniProt Gene Name    CRP [Similar Products]
 UniProt Synonym Gene Names    PTX1 [Similar Products]
 UniProt Entry Name    CRP_HUMAN
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 NCBI Summary for CRP    The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]
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 UniProt Comments for CRP    CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1q23.2

Cellular Component: extracellular space; growth cone; extracellular region; filopodium

Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; low-density lipoprotein binding; cholesterol binding; virion binding; calcium ion binding

Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; negative regulation of vasodilation; wound healing; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging
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 Research Articles on CRP    1. Elevated hs-CRP levels were associated with increased risk of disabling dementia in individuals with history of stroke but not in those without it.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CRP human serumPathways associated with CRP human serum
 Reference Product  PubMed Publications
 STAT3 human serum  >37 publications with CRP and STAT3
 C1S human serum  >12 publications with CRP and C1S
 C1R human serum  >12 publications with CRP and C1R
 APCS human serum  >11 publications with CRP and APCS
 LEP human serum  >10 publications with CRP and LEP
 FCGR2B human serum  >8 publications with CRP and FCGR2B
 FCGR2A human serum  >7 publications with CRP and FCGR2A
 C1QB human serum  >2 publications with CRP and C1QB
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 IL6-mediated Signaling Events Pathway antibodies  IL6-mediated Signaling Events Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with CRP human serumOrgans/Tissues associated with CRP human serum
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >12214 publications with CRP and Inflammation
 Cardiovascular Diseases Antibodies  >8824 publications with CRP and Cardiovascular Diseases
 Infection Antibodies  >4796 publications with CRP and Infection
 Heart Diseases Antibodies  >4207 publications with CRP and Heart Diseases
 Metabolic Diseases Antibodies  >4023 publications with CRP and Metabolic Diseases
 Necrosis Antibodies  >3404 publications with CRP and Necrosis
 Myocardial Ischemia Antibodies  >3355 publications with CRP and Myocardial Ischemia
 Atherosclerosis Antibodies  >2986 publications with CRP and Atherosclerosis
 Obesity Antibodies  >2134 publications with CRP and Obesity
 Arthritis, Rheumatoid Antibodies  >2118 publications with CRP and Arthritis, Rheumatoid
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >1509 publications with CRP and Liver
 Pancreas Antibodies  >159 publications with CRP and Pancreas
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