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DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

IGHG4 immunoglobulin :: IgG4, Human Myeloma Plasma Immunoglobulin

Scan QR to view Datasheet Catalog #    MBS135576
Testing Data
Unit / Price
1 mg  /  $590 +1 FREE 8GB USB
5 mg  /  $1,785 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

IgG4, Human Myeloma Plasma (IGHG4), Immunoglobulin

★Popular Item★
 Also Known As   

IgG4, Human Myeloma Plasma

 Product Gene Name   

IGHG4 immunoglobulin

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 14; NC_000014.8 (106090813..106092402, complement). Location: 14q32.33
 OMIM    147130
 3D Structure    ModBase 3D Structure for P01861
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 Host    Human myeloma plasma
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 Purity/Purification    >95% by SDS-PAGE analysis
 Form/Format    Frozen liquid
 Concentration    1.0 mg/ml (lot specific)
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 Buffer    0.02M Sodium Phosphate; 0.15M NaCl; 0.05% Azide; pH 7.4
 Extinction Coefficient    1.36
 Preservative    SodiumAzide
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 Preparation and Storage    Store at -70 degree C. Shelf Life: 3 years from delivery
 Other Notes    Small volumes of IGHG4 immunoglobulin vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for IGHG4 immunoglobulin

   IgG4 antibodies will dominate the IgG response in schistosomiasis, lymphatic filariasis, and in patients after allergen immunotherapy. Unlike the other IgG subclasses, IgG4 does not activate complement. A combined IgA-IgG4 deficiency has been associated with, recurrent pyogenic infections. Prepared from myeloma plasma shown to be non reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. >95 percent pure by SDS-PAGE.
 Product Categories/Family for IGHG4 immunoglobulin    Human Immunoglobulins; Human Immunoglobulins
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 Testing Data of IGHG4 immunoglobulin    IGHG4 immunoglobulin Testing Data image
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NCBI/Uniprot data below describe general gene information for IGHG4. It may not necessarily be applicable to this product.
 NCBI GI #    121047
 NCBI GeneID    3503
 NCBI Accession #    P01861.1 [Other Products]
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 UniProt Primary Accession #    P01861 [Other Products]
 UniProt Related Accession #    P01861 [Other Products]
 Molecular Weight    146,000
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 NCBI Official Full Name    Ig gamma-4 chain C region
 NCBI Official Synonym Full Names    immunoglobulin heavy constant gamma 4 (G4m marker)
 NCBI Official Symbol    IGHG4 [Similar Products]
 UniProt Protein Name    Ig gamma-4 chain C region
 Protein Family    Ig gamma-4 chain C region
 UniProt Gene Name    IGHG4 [Similar Products]
 UniProt Entry Name    IGHG4_HUMAN
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 UniProt Comments for IGHG4    IGHG4:

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: innate immune response; complement activation, classical pathway; complement activation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IGHG4 immunoglobulinOrgans/Tissues associated with IGHG4 immunoglobulin
 Products by Pathway  Pathway Diagram
 Classical Antibody-mediated Complement Activation Pathway antibodies  Classical Antibody-mediated Complement Activation Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 Creation Of C4 And C2 Activators Pathway antibodies  Creation Of C4 And C2 Activators Pathway Diagram
 FCGR Activation Pathway antibodies  FCGR Activation Pathway Diagram
 Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway antibodies  Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Initial Triggering Of Complement Pathway antibodies  Initial Triggering Of Complement Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway antibodies  Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway Diagram
 Role Of Phospholipids In Phagocytosis Pathway antibodies  Role Of Phospholipids In Phagocytosis Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >3 publications with IGHG4 and Blood
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