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Leukotactin/Mip-5 Lysate

Scan QR to view Datasheet Catalog #    MBS570449 Leukotactin/Mip-5 lysate
Unit / Price
0.02 mg  /  $620 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Leukotactin/Mip-5, Lysate

 Also Known As   

Leukotactin/Mip-5 - Control Lysate

 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Species Reactivity    Human
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 Form/Format    Provided as solution in phosphate buffered saline with 0.08% sodium azide.
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 Source Note    Hybridoma produced by the fusion of splenocytes from mice immunized with cytoskeleton preparation of HeLa cells and mouse myeloma cells.
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 Preparation and Storage    Store at -20 degree C.
 Other Notes    Small volumes of Leukotactin/Mip-5 lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for Leukotactin/Mip-5 lysate

   Leukotactin-1 (Lkn-1), also known as Macrophage inflammatory protein 1 delta (MIP-1), MIP-5, HCC-2, and NCC-3, is a novel human CC chemokine whose gene was mapped to human chromosome 17 adjacent to the HCC-1 gene. Lkn-1, together with mouse C10, mouse MIP-1 and human MPIF-1, constitute a subgroup of CC chemokines which contain six instead of four conserved cysteine residues. The two additional cysteine residues in Lkn-1 have been shown to form a third disulfide bond. Lkn-1 cDNA encodes a 113 amino acid precursor protein with a putative signal peptide of 21 aa residues that is cleaved to generate a 92 amino acid mature protein. In recombinant Lkn-1 preparations produced in insect cells and in yeast, amino-terminal truncations were found to have occurred. The major forms of Lkn-1 secreted by insect cells and yeast were reported to be proteins of 68 and 66 amino acids, respectively. The full length and the amino-terminal truncated forms of human Lkn-1 have been shown to be potent chemoattractants for monocytes and T-lymphocytes. These proteins can also chemoattract eosinophils and have been shown to induce calcium flux in human CCR-1 transfected cells. Additionally, Lkn-1 can suppress colony formation by human granulocyte-macrophage, erythroid, and multipotential progenitor cells stimulated by combinations of growth factors.
 Applications Tested/Suitable for Leukotactin/Mip-5 lysate   

Activity Assay, Western Blot (WB)

 Application Notes for Leukotactin/Mip-5 lysate    Detects Keratin 5 & 8 by Western blot. Detects a 58 kDa band, corresponding to Keratin 5, and a 52.5 kDa band, corresponding to Keratin 8.
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Product References and Citations for Leukotactin/Mip-5 lysate

   1. Kovarik, et al, J. Tumor Marker Oncol. 1990, 5, 219
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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