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FGG native protein :: Fibrinogen Native Protein

Scan QR to view Datasheet Catalog #    MBS537444 FGG native protein
Unit / Price
1 g  /  $355 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Fibrinogen (FGG), Native Protein

★Popular Item★
 Also Known As   

Fibrinogen protein

 Product Synonym Names    Fg protein
 Product Gene Name   

FGG native protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for P12799
 Host    Human
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 Purity/Purification    > 95% pure
 Form/Format    20mM sodium citrate-HCl buffer, pH 7.4. Plasminogen Depleted.
 Concentration    43.77 mg/ml (lot specific)
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 Source Note    Human plasma
 Protein Type    Native
 Biological Significance    Fibrinogen (factor I) is a soluble plasma glycoprotein, synthesised by the liver, that is converted by thrombin into fibrin during blood coagulation. This is achieved through processes in the coagulation cascade that activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin.
 Biohazard Information    Human plasma tested negative against anti-HIV1/2, anti-HTLV I & II, anti-HCV, HbsAg, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors also screened for Creutzfeldt-Jakob Disease.
 Dry Ice Shipment    Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
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 Preparation and Storage    Aliquot and store at -70 degree C or lower. Avoid repeated freeze/thaw cycles
 Other Notes    Small volumes of FGG native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for FGG native protein

   Highly purified native Fibrinogen protein
 Product Categories/Family for FGG native protein    Immunology; Native Protein
 Applications Tested/Suitable for FGG native protein   

User optimized

 Application Notes for FGG native protein    100% Clottable
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NCBI/Uniprot data below describe general gene information for FGG. It may not necessarily be applicable to this product.
 NCBI GI #    350
 NCBI GeneID    280792
 NCBI Accession #    CAA33562.1 [Other Products]
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 UniProt Primary Accession #    P12799 [Other Products]
 UniProt Related Accession #    P12799 [Other Products]
 Molecular Weight    50,244 Da [Similar Products]
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 NCBI Official Full Name    fibrinogen
 NCBI Official Symbol    FGG [Similar Products]
 NCBI Protein Information    fibrinogen gamma-B chain
 UniProt Protein Name    Fibrinogen gamma-B chain
 Protein Family    Fibrinogen
 UniProt Gene Name    FGG [Similar Products]
 UniProt Synonym Gene Names    Gamma' [Similar Products]
 UniProt Entry Name    FIBG_BOVIN
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 UniProt Comments for FGG    Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with FGG native proteinPathways associated with FGG native protein
 Reference Product  PubMed Publications
 FGA native protein  >86 publications with FGG and FGA
 FGB native protein  >84 publications with FGG and FGB
 F13A1 native protein  >4 publications with FGG and F13A1
 ITGB3 native protein  >2 publications with FGG and ITGB3
 ITGA2B native protein  >1 publications with FGG and ITGA2B
 ITGB2 native protein  >1 publications with FGG and ITGB2
 Products by Pathway  Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Platelet Activation Pathway antibodies  Platelet Activation Pathway Diagram
 Staphylococcus Aureus Infection Pathway antibodies  Staphylococcus Aureus Infection Pathway Diagram
 Staphylococcus Aureus Infection Pathway antibodies  Staphylococcus Aureus Infection Pathway Diagram
Diseases associated with FGG native proteinOrgans/Tissues associated with FGG native protein
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >165 publications with FGG and Cardiovascular Diseases
 Brain Diseases Antibodies  >93 publications with FGG and Brain Diseases
 Heart Diseases Antibodies  >83 publications with FGG and Heart Diseases
 Death Antibodies  >57 publications with FGG and Death
 Lung Diseases Antibodies  >45 publications with FGG and Lung Diseases
 Thrombosis Antibodies  >37 publications with FGG and Thrombosis
 Inflammation Antibodies  >37 publications with FGG and Inflammation
 Liver Diseases Antibodies  >33 publications with FGG and Liver Diseases
 Kidney Diseases Antibodies  >27 publications with FGG and Kidney Diseases
 Hypertension Antibodies  >20 publications with FGG and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >74 publications with FGG and Brain
 Muscle Antibodies  >58 publications with FGG and Muscle
 Liver Antibodies  >55 publications with FGG and Liver
 Embryonic Tissue Antibodies  >14 publications with FGG and Embryonic Tissue
 Testis Antibodies  >13 publications with FGG and Testis
 Reticulum Antibodies  >8 publications with FGG and Reticulum
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