NP_000604.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
hemopexin
NCBI Official Synonym Full Names
hemopexin
NCBI Official Synonym Symbols
NCBI Protein Information
hemopexin; beta-1B-glycoprotein
UniProt Protein Name
Hemopexin
UniProt Synonym Protein Names
Beta-1B-glycoprotein
UniProt Entry Name
HEMO_HUMAN
NCBI Summary for HPX
This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009]
UniProt Comments for HPX
HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11p15.5-p15.4
Cellular Component: extracellular space; extracellular region
Molecular Function: protein binding; metal ion binding; heme transporter activity
Biological Process: positive regulation of humoral immune response mediated by circulating immunoglobulin; receptor-mediated endocytosis; heme transport; positive regulation of tyrosine phosphorylation of Stat1 protein; positive regulation of immunoglobulin production; viral reproduction; hemoglobin metabolic process; cellular iron ion homeostasis; heme metabolic process
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Products associated with HPX native protein
Pathways associated with HPX native protein
Diseases associated with HPX native protein
Organs/Tissues associated with HPX native protein
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