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PNLIP native protein :: Lipase Native Protein

Scan QR to view Datasheet Catalog #    MBS537851 PNLIP native protein
Unit / Price
0.1 mg  /  $485 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Lipase (PNLIP), Native Protein

★Popular Item★
 Also Known As   

Lipase protein

 Product Synonym Names    Lipase Enzyme
 Product Gene Name   

PNLIP native protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    246600
 3D Structure    ModBase 3D Structure for P16233
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 Host    Human
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 Form/Format    100 mM Tris, pH 8.0, with 100 mM NaCl, 1mM Benzamidine and 1mM CaCl2.
 Concentration    1.7 mg/ml (lot specific)
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 Source Note    Human pancreas
 Protein Type    Native
 Biological Significance    A lipase is a water-soluble enzyme that catalyzes the hydrolysis of ester chemical bonds in water-insoluble lipid substrates. Lipases are a subclass of the esterases. They perform essential roles in the digestion, transport and processing of dietary lipids in most, if not all, living organisms. Genes encoding lipases are even present in certain viruses.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of PNLIP native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for PNLIP native protein

   Purified native Human Lipase protein
 Product Categories/Family for PNLIP native protein    Proteases, Inhibitors, & Enzymes; Native Protein
 Applications Tested/Suitable for PNLIP native protein   

User optimized

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NCBI/Uniprot data below describe general gene information for PNLIP. It may not necessarily be applicable to this product.
 NCBI GI #    190140
 NCBI GeneID    5406
 NCBI Accession #    AAA60129.1 [Other Products]
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 UniProt Primary Accession #    P16233 [Other Products]
 UniProt Secondary Accession #    Q5VSQ2 [Other Products]
 UniProt Related Accession #    P16233 [Other Products]
 Molecular Weight    51,157 Da [Similar Products]
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 NCBI Official Full Name    lipase
 NCBI Official Synonym Full Names    pancreatic lipase
 NCBI Official Symbol    PNLIP [Similar Products]
 NCBI Official Synonym Symbols   
PL; PTL; PNLIPD
[Similar Products]
 NCBI Protein Information    pancreatic triacylglycerol lipase
 UniProt Protein Name    Pancreatic triacylglycerol lipase
 Protein Family    Lipase
 UniProt Gene Name    PNLIP [Similar Products]
 UniProt Synonym Gene Names    PL; PTL; Pancreatic lipase [Similar Products]
 UniProt Entry Name    LIPP_HUMAN
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 NCBI Summary for PNLIP    This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PNLIP    PNLIP: a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]

Protein type: Secreted, signal peptide; EC 3.1.1.3; Lipid Metabolism - glycerolipid; Hydrolase; Secreted

Chromosomal Location of Human Ortholog: 10q26.1

Cellular Component: extracellular region

Molecular Function: triacylglycerol lipase activity; metal ion binding

Biological Process: phototransduction, visible light; cholesterol absorption; retinoid metabolic process; lipid digestion; lipid catabolic process

Disease: Pancreatic Lipase Deficiency
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 Research Articles on PNLIP    1. All these findings support the use of YLLIP2 in enzyme replacement therapy for the treatment of pancreatic exocrine insufficiency, a pathological situation in which an acidification of intestinal contents occurs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PNLIP native proteinPathways associated with PNLIP native protein
 Reference Product  PubMed Publications
 CLPS native protein  >3 publications with PNLIP and CLPS
 CEL native protein  >1 publications with PNLIP and CEL
 Products by Pathway  Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Digestion Of Dietary Lipid Pathway antibodies  Digestion Of Dietary Lipid Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with PNLIP native proteinOrgans/Tissues associated with PNLIP native protein
 Disease Name  Pubmed Publications
 Pancreatitis Antibodies  >13 publications with PNLIP and Pancreatitis
 Weight Loss Antibodies  >5 publications with PNLIP and Weight Loss
 Diabetes Mellitus Antibodies  >4 publications with PNLIP and Diabetes Mellitus
 Hyperlipidemias Antibodies  >4 publications with PNLIP and Hyperlipidemias
 Insulin Resistance Antibodies  >3 publications with PNLIP and Insulin Resistance
 Cardiovascular Diseases Antibodies  >3 publications with PNLIP and Cardiovascular Diseases
 Hypertriglyceridemia Antibodies  >3 publications with PNLIP and Hypertriglyceridemia
 Heart Diseases Antibodies  >2 publications with PNLIP and Heart Diseases
 Fibrosis Antibodies  >2 publications with PNLIP and Fibrosis
 Necrosis Antibodies  >2 publications with PNLIP and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >27 publications with PNLIP and Pancreas
 Liver Antibodies  >4 publications with PNLIP and Liver
 Adipose Tissue Antibodies  >3 publications with PNLIP and Adipose Tissue
 Heart Antibodies  >1 publications with PNLIP and Heart
 Connective Tissue Antibodies  >1 publications with PNLIP and Connective Tissue
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