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bNEFM native protein :: Neurofilament Medium Native Protein

Scan QR to view Datasheet Catalog #    MBS143075 bNEFM native protein
Unit / Price
0.002 mg  /  $140 +1 FREE 8GB USB
0.01 mg  /  $205 +1 FREE 8GB USB
1 mg  /  $3,515 +4 FREE 8GB USB
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 Product Name   

Neurofilament Medium (bNEFM), Native Protein

★Popular Item★
 Also Known As   

Bovine Neurofilament Medium Polypeptide

 Product Synonym Names    NEFM; Neurofilament Medium Polypeptide Bovine; Neurofilament medium polypeptide; NF-M; Neurofilament triplet M protein; 160 kDa neurofilament protein; Neurofilament 3; NEFM; NEF3; NFM
 Product Gene Name   

bNEFM native protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for O77788
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 Purity/Purification    Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
 Form/Format    The protein was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate, pH-7.5, 2mM DTT, 6M urea and 1mM EDTA.
Sterile Filtered White lyophilized (freeze-dried) powder.
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 Source    Bovine Spinal Cord
 Solubility    It is recommended to reconstitute the lyophilized NEFM in sterile 18M Omega-cm H2O.
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 Preparation and Storage    Lyophilized NEFM although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution NEFM should be stored at 4C between 2-7 days and for future use below -18C.
Please prevent freeze-thaw cycles.
 Other Notes    Small volumes of bNEFM native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for bNEFM native protein

   Description: Ultra Pure NeuroFilament Protein having a Molecular mass of 160 kDa produced from Bovine Spinal Cord.

Introduction: Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites. NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
 Product Categories/Family for bNEFM native protein    RECOMBINANT & NATURAL PROTEINS; Natural Proteins
NCBI/Uniprot data below describe general gene information for bNEFM. It may not necessarily be applicable to this product.
 NCBI GI #    143811427
 NCBI GeneID    281347
 NCBI Accession #    O77788.3 [Other Products]
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 UniProt Primary Accession #    O77788 [Other Products]
 UniProt Related Accession #    O77788 [Other Products]
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 NCBI Official Full Name    Neurofilament medium polypeptide
 NCBI Official Synonym Full Names    neurofilament, medium polypeptide
 NCBI Official Symbol    NEFM [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    neurofilament medium polypeptide; 160 kDa neurofilament protein; major neuronal intermediate filament subunit; neurofilament 3; neurofilament M subunit; neurofilament triplet M protein
 UniProt Protein Name    Neurofilament medium polypeptide
 UniProt Synonym Protein Names   
160 kDa neurofilament protein; Neurofilament 3; Neurofilament triplet M protein
 Protein Family    Neurofilament medium polypeptide
 UniProt Gene Name    NEFM [Similar Products]
 UniProt Synonym Gene Names    NEF3; NFM; NF-M [Similar Products]
 UniProt Entry Name    NFM_BOVIN
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 UniProt Comments for bNEFM    NFM: a neurofilament intermediate filament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The levels of phosphorylation are altered developmentally and coincident with a change in the neurofilament function.

Protein type: Cytoskeletal

Cellular Component: neurofilament

Molecular Function: structural molecule activity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with bNEFM native proteinPathways associated with bNEFM native protein
 Reference Product  PubMed Publications
 NEFL native protein  >2 publications with bNEFM and NEFL
 GFAP native protein  >1 publications with bNEFM and GFAP
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Organs/Tissues associated with bNEFM native protein
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with bNEFM and Brain
 Embryonic Tissue Antibodies  >1 publications with bNEFM and Embryonic Tissue
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