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SHBG native protein

Scan QR to view Datasheet Catalog #    MBS537806 SHBG native protein
Unit / Price
1 mg  /  $1,415 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SHBG, Native Protein

★Popular Item★
 Also Known As   

SHBG protein

 Product Synonym Names    Sex Hormone Binding Globulin protein
 Product Gene Name   

SHBG native protein

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    182205
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 Purity/Purification    > 90% pure
 Form/Format    Supplied lyophilized from 20mM NH4HCO3. May contain traces of buffer salts. Reconstitute with Phosphate buffer, with 150mM Sodium Chloride, pH >7.0.
 Concentration    1.0mg per vial; lyophilized (lot specific)
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 Source    Normal Serum/Human plasma
 Species    Human
 Grade    Highly Pure
 Protein Type    Native
 Biological Significance    SHBG transports the sex steroids testosterone, DHT and estradiol in the blood. Serum levels are increased during pregnancy, in women taking estrogens, and in men over the age of 50. Levels are reduced after menopause and in response to treatment with androgens or corticosteroids. Diagnostic uses include polycystic ovary disease and tests for liver and thyroid function.
 Contaminants    SDS-PAGE shows a major band corresponding to a molecular weight of approximately 45 kD.
 Biohazard    Raw material tested at the donor level anf found negative for HIV I& II antibodies, HCV antibodies and HBsAg by FDA approved methods.
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 Preparation and Storage    Ships at 4 degree C, upon receipt store at -70 degree C long term. Avoid repeated freeze/thaw cycles
 Other Notes    Small volumes of SHBG native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for SHBG native protein

   Purified native Human SHBG protein
 Product Categories/Family for SHBG native protein    Hormones & Steroids; Native Protein
 Applications Tested/Suitable for SHBG native protein   

User optimized

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NCBI/Uniprot data below describe general gene information for SHBG. It may not necessarily be applicable to this product.
 NCBI GI #    338075
 NCBI Accession #    AAC18778.1 [Other Products]
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 UniProt Secondary Accession #    P14689; Q16616; Q3MIL0; Q6ISD2; B0FWH4; E9PGW1; F5H5Z8; I3L1N7 [Other Products]
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 NCBI Official Full Name    sex hormone-binding globulin
 UniProt Protein Name    Sex hormone-binding globulin
 UniProt Synonym Protein Names   
Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin
 Protein Family    Sex hormone-binding globulin
 UniProt Gene Name    SHBG [Similar Products]
 UniProt Synonym Gene Names    SHBG; SBP; ABP; TeBG [Similar Products]
 UniProt Entry Name    SHBG_HUMAN
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 UniProt Comments for SHBG    SHBG: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: extracellular region

Molecular Function: androgen binding

Biological Process: primary spermatocyte growth
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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