View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List Scl-70 native protein Catalog # MBS537330 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Scl-70, Native Protein Popular Item Full Product Name Scl-70 protein Product Synonym Names Scleroderma protein; Scl70 protein; Scl-70; Scl- 70; Scl--70; Scl--70 protein; Scl- 70 protein Product Gene Name Scl-70 native protein[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Host Bovine Purity/Purification > 90% pure Form/Format Supplied in 20 mM Hepes-NaOH, pH 7.5; 0.32 M NaCl; 0.1 mM PMSF; 0.2 mM DTT; 0.1% (v/v) Micr-O-protect; 20% (v/v) glycerol Concentration 0.807 ug/ml (lot specific) Source Note Calf Thymus Protein Type Native Biological Significance Scl-70 is an antigen present on topoisomerase I, which is an ubiquitous intranuclear enzyme that mediates the twisting and untwisting of the DNA helix during gene transcription. It is a basic nuclear protein with a molecular weight of 70,000 daltons. Antibodies directed against Scl-70 usually give a nucleolar ANA pattern and are present exclusively in 70% of patients with severe, diffuse forms of progressive systemic sclerosis, also known as scleroderma. Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. Dry Ice Shipment Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Preparation and Storage Store at -20 degree C Other Notes Small volumes of Scl-70 native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for Scl-70 native protein Purified Native Bovine Scl-70 protein Product Categories/Family for Scl-70 native protein Proteases; Inhibitors; & Enzymes; Native Protein Applications Tested/Suitable for Scl-70 native protein User optimized TOP Molecular Weight 68-75 kDa TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP