NP_064524.3
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
3-hydroxybutyrate dehydrogenase type 2
NCBI Official Synonym Full Names
3-hydroxybutyrate dehydrogenase, type 2
NCBI Official Synonym Symbols
DHRS6; EFA6R; SDR15C1; UCPA-OR; UNQ6308; PRO20933 [Similar Products]
NCBI Protein Information
3-hydroxybutyrate dehydrogenase type 2; oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; dehydrogenase/reductase SDR family member 6; short chain dehydrogenase/reductase family 15C, member 1
UniProt Protein Name
3-hydroxybutyrate dehydrogenase type 2
UniProt Synonym Protein Names
Dehydrogenase/reductase SDR family member 6; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase
UniProt Synonym Gene Names
UniProt Entry Name
BDH2_HUMAN
UniProt Comments for BDH2
Function: Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase
By similarity. Ref.8
Catalytic activity: (R)-3-hydroxybutanoate + NAD+ = acetoacetate + NADH.
Pathway: Siderophore biosynthesis.
Subunit structure: Homotetramer. Ref.8
Subcellular location: Cytoplasm Ref.8.
Sequence similarities: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Biophysicochemical propertiesKinetic parameters:KM=60 µM for NAD Ref.8KM=10 mM for R-hydroxybutyrateVmax=82 nmol/min/mg enzyme (at 30 degrees Celsius)pH dependence:Optimum pH is 7.5-9.0.
Research Articles on BDH2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with BDH2 peptide
Pathways associated with BDH2 peptide
Diseases associated with BDH2 peptide
Organs/Tissues associated with BDH2 peptide
|