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AADACL1 peptide

Scan QR to view Datasheet Catalog #    MBS425438 AADACL1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AADACL1, Peptide

★Popular Item★
 Also Known As   

AADACL1 Immunizing Peptide

 Product Synonym Names    AADACL1; arylacetamide deacetylase-like 1
 Product Gene Name   

AADACL1 peptide

[Similar Products]
 Antibody/Peptide Pairs    AADACL1 peptide (MBS425438) is used for blocking the activity of AADACL1 antibody (MBS421592)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-RTRNSYIK WLDQN
 OMIM    613234
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 Species Reactivity    Human, Mouse, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of AADACL1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for AADACL1. It may not necessarily be applicable to this product.
 NCBI GI #    68051721
 NCBI GeneID    57552
 NCBI Accession #    NP_065843.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_020792.4 [Other Products]
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 UniProt Secondary Accession #    Q86WZ1; Q9P2I4; B7Z2K4; B7Z3A1; B7Z5U2; B7Z906; B7ZAW6; F5H7K4 [Other Products]
 UniProt Related Accession #    Q6PIU2 [Other Products]
 Molecular Weight    31,168 Da
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 NCBI Official Full Name    neutral cholesterol ester hydrolase 1 isoform b
 NCBI Official Synonym Full Names    neutral cholesterol ester hydrolase 1
 NCBI Official Symbol    NCEH1 [Similar Products]
 NCBI Official Synonym Symbols   
NCEH; AADACL1
[Similar Products]
 NCBI Protein Information    neutral cholesterol ester hydrolase 1
 UniProt Protein Name    Neutral cholesterol ester hydrolase 1
 UniProt Synonym Protein Names   
Arylacetamide deacetylase-like 1
 UniProt Gene Name    NCEH1 [Similar Products]
 UniProt Synonym Gene Names    AADACL1; KIAA1363; NCEH [Similar Products]
 UniProt Entry Name    NCEH1_HUMAN
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 UniProt Comments for AADACL1    AADACL1: a single-pass type II membrane microsomal protein. Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (acetyl-glyceryl-ether-phosphorylcholine). Elevated in invasive cancer cells from several different tumor types. May be involved in the elevated neutral ether lipid content and elevated LPA signaling in cancer cells. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration. A key enzymatic node regulating an ether lipid signaling network in cancer; regulates MAGE and lysophospholipid levels in invasive cancer cells. Three alternatively spliced human isoforms have been described.

Protein type: EC 3.1.1.-; Membrane protein, integral; Hydrolase

Chromosomal Location of Human Ortholog: 3q26.31

Cellular Component: endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: sterol esterase activity

Biological Process: lipid catabolic process
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 Research Articles on AADACL1    1. Pioglitazone increases ABCA1 expression in an LXR-dependent manner and NCEH1 expression in an LXRalpha-independent manner.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AADACL1 peptideDiseases associated with AADACL1 peptide
 Products by Pathway  Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with AADACL1 and Inflammation
 Ataxia Antibodies  >1 publications with AADACL1 and Ataxia
 Neoplasm Invasiveness Antibodies  >1 publications with AADACL1 and Neoplasm Invasiveness
 Liver Diseases Antibodies  >1 publications with AADACL1 and Liver Diseases
 Neoplasms, Experimental Antibodies  >1 publications with AADACL1 and Neoplasms, Experimental
 Memory Disorders Antibodies  >1 publications with AADACL1 and Memory Disorders
 Fatty Liver Antibodies  >1 publications with AADACL1 and Fatty Liver
Organs/Tissues associated with AADACL1 peptide
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with AADACL1 and Liver
 Brain Antibodies  >5 publications with AADACL1 and Brain
 Muscle Antibodies  >3 publications with AADACL1 and Muscle
 Vascular Antibodies  >3 publications with AADACL1 and Vascular
 Lung Antibodies  >2 publications with AADACL1 and Lung
 Prostate Antibodies  >2 publications with AADACL1 and Prostate
 Kidney Antibodies  >2 publications with AADACL1 and Kidney
 Testis Antibodies  >1 publications with AADACL1 and Testis
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