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ABCA5 peptide

Scan QR to view Datasheet Catalog #    MBS426643 ABCA5 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCA5, Peptide

★Popular Item★
 Also Known As   

ABCA5 Immunizing Peptide

 Product Synonym Names    ABCA5; ATP-binding cassette, sub-family A (ABC1), member 5; ABC13; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; ATP-binding cassette A5; ATP-binding cassette, sub-family A, member 5
 Product Gene Name   

ABCA5 peptide

[Similar Products]
 Antibody/Peptide Pairs    ABCA5 peptide (MBS426643) is used for blocking the activity of ABCA5 antibody (MBS421977)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    DYSSETSEDD DSLKC
 OMIM    612503
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of ABCA5 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ABCA5. It may not necessarily be applicable to this product.
 NCBI GI #    27262626
 NCBI GeneID    23461
 NCBI Accession #    NP_758424.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_172232.3 [Other Products]
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 UniProt Secondary Accession #    Q8IVJ2; Q96LJ1; Q96MS4; Q96PZ9; Q9NY14 [Other Products]
 UniProt Related Accession #    Q8WWZ7 [Other Products]
 Molecular Weight    99,273 Da
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 NCBI Official Full Name    ATP-binding cassette sub-family A member 5
 NCBI Official Synonym Full Names    ATP binding cassette subfamily A member 5
 NCBI Official Symbol    ABCA5 [Similar Products]
 NCBI Official Synonym Symbols   
ABC13; EST90625
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family A member 5
 UniProt Protein Name    ATP-binding cassette sub-family A member 5
 Protein Family    ABC transporter A family
 UniProt Gene Name    ABCA5 [Similar Products]
 UniProt Synonym Gene Names    KIAA1888 [Similar Products]
 UniProt Entry Name    ABCA5_HUMAN
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 NCBI Summary for ABCA5    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCA5    ABCA5: May play a role in the processing of autolysosomes. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: Golgi membrane; integral to membrane; intracellular membrane-bound organelle; late endosome; late endosome membrane; lysosomal membrane; lysosome

Molecular Function: ATP binding; ATPase activity, coupled to transmembrane movement of substances

Biological Process: cholesterol efflux; lipid transport; metabolic process; reverse cholesterol transport; transmembrane transport
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 Research Articles on ABCA5    1. This report represents the first extensive expression and functional study of ABCA5 in the human brain and our data suggest a plausible function of ABCA5 in the brain as a cholesterol transporter associated with Abeta generation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ABCA5 peptideDiseases associated with ABCA5 peptide
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >6 publications with ABCA5 and Skin Diseases
 Brain Diseases Antibodies  >4 publications with ABCA5 and Brain Diseases
 Congenital Abnormalities Antibodies  >3 publications with ABCA5 and Congenital Abnormalities
 Ovarian Neoplasms Antibodies  >2 publications with ABCA5 and Ovarian Neoplasms
 Lung Neoplasms Antibodies  >2 publications with ABCA5 and Lung Neoplasms
 Nervous System Diseases Antibodies  >2 publications with ABCA5 and Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with ABCA5 and Cell Transformation, Neoplastic
 Neoplasm Metastasis Antibodies  >1 publications with ABCA5 and Neoplasm Metastasis
 Hyperplasia Antibodies  >1 publications with ABCA5 and Hyperplasia
 Liver Neoplasms Antibodies  >1 publications with ABCA5 and Liver Neoplasms
Organs/Tissues associated with ABCA5 peptide
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with ABCA5 and Brain
 Liver Antibodies  >4 publications with ABCA5 and Liver
 Kidney Antibodies  >4 publications with ABCA5 and Kidney
 Testis Antibodies  >3 publications with ABCA5 and Testis
 Lung Antibodies  >3 publications with ABCA5 and Lung
 Skin Antibodies  >3 publications with ABCA5 and Skin
 Bone Antibodies  >2 publications with ABCA5 and Bone
 Prostate Antibodies  >2 publications with ABCA5 and Prostate
 Vascular Antibodies  >1 publications with ABCA5 and Vascular
 Pancreas Antibodies  >1 publications with ABCA5 and Pancreas
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