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| Product Name
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AKAP9 / AKAP450 / CG-NAP, Peptide
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| Also Known As
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AKAP9 / AKAP450 / CG-NAP Immunizing Peptide
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| Product Synonym Names
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AKAP9; CG-NAP; PRKA9; YOTIAO; AKAP350; HYPERION; KIAA0803; A kinase (PRKA) anchor protein (yotiao) 9; AKAP120-like protein; kinase N-associated protein; A-kinase anchoring protein 450; A-kinase anchor protein, 350kDa; protein kinase A anchoring protein 9; AKAP9 / AKAP450 / CG-NAP
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| Product Gene Name
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[Similar Products]
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| Product Synonym Gene Name
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AKAP450; CG-NAP
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[Similar Products]
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| Antibody/Peptide Pairs
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AKAP9 / AKAP450 / CG-NAP peptide (MBS428449) is used for blocking the activity of AKAP9/AKAP450/CG-NAP antibody (MBS420313)
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| Sequence
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C-SGSTTQFH AGMR
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| OMIM
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604001
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| Species Reactivity
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Human, Mouse
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| Form/Format
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100ug of dried peptide
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| Preparation and Storage
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Shipped at ambient temperature, store at -20 degree C
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| ISO Certification
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Manufactured in an ISO 9001:2015 Certified Laboratory.
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| Other Notes
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Small volumes of AKAP9 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| NCBI/Uniprot data below describe general gene information for AKAP9. It may not necessarily be applicable to this product. |
| NCBI GI #
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22538387
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| NCBI GeneID
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10142
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| NCBI Accession #
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NP_005742.4
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[Other Products]
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| NCBI Related Accession #
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NP_671714.1
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_005751.4
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[Other Products]
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| UniProt Secondary Accession #
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O14869; O43355; O94895; Q75N20; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2; A4D1F0; A4D1F2; A4D1F4
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[Other Products]
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| UniProt Related Accession #
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Q99996
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[Other Products]
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| Molecular Weight
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455,423 Da
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TOP
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| NCBI Official Full Name
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A-kinase anchor protein 9 isoform 2
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| NCBI Official Synonym Full Names
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A-kinase anchoring protein 9
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| NCBI Official Symbol
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AKAP9
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[Similar Products]
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| NCBI Official Synonym Symbols
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LQT11; PRKA9; AKAP-9; CG-NAP; YOTIAO; AKAP350; AKAP450; PPP1R45; HYPERION; MU-RMS-40.16A
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[Similar Products]
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| NCBI Protein Information
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A-kinase anchor protein 9
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| UniProt Protein Name
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A-kinase anchor protein 9
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| UniProt Synonym Protein Names
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A-kinase anchor protein 350 kDa; AKAP 350; hgAKAP 350; A-kinase anchor protein 450 kDa; AKAP 450; AKAP 120-like protein; Centrosome- and Golgi-localized PKN-associated protein
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| Protein Family
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A-kinase anchor protein
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| UniProt Gene Name
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AKAP9
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[Similar Products]
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| UniProt Synonym Gene Names
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AKAP350; AKAP450; KIAA0803; PRKA9
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[Similar Products]
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| UniProt Entry Name
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AKAP9_HUMAN
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| NCBI Summary for AKAP9
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]
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| UniProt Comments for AKAP9
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AKAP9: Binds to type II regulatory subunits of protein kinase A. Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. May be required to maintain the integrity of the Golgi apparatus. Isoform 4 is associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations. Defects in AKAP9 are the cause of long QT syndrome type 11 (LQT11). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 7q21-q22
Cellular Component: centrosome; cis-Golgi network; cytoskeleton; cytosol; Golgi apparatus; Golgi stack; intracellular membrane-bound organelle; voltage-gated potassium channel complex
Molecular Function: potassium channel regulator activity; protein binding; protein complex scaffold; Ras guanyl-nucleotide exchange factor activity; receptor binding
Biological Process: G2/M transition of mitotic cell cycle; MAPKKK cascade; microtubule nucleation; positive regulation of GTPase activity; positive regulation of peptidyl-serine phosphorylation; signal transduction; synaptic transmission; transport
Disease: Long Qt Syndrome 11
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TOP
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| Research Articles on AKAP9
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1. Study suggests a role of rare missense variants at NRXN1 and AKAP9 in schizophrenia susceptibility, probably related to alteration of the excitatory/inhibitory synaptic balance, deserving further investigation
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Products associated with AKAP9 peptide | Pathways associated with AKAP9 peptide |
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| Diseases associated with AKAP9 peptide | Organs/Tissues associated with AKAP9 peptide |
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Peptide 
