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AKAP9 peptide :: AKAP9 / AKAP450 / CG-NAP Peptide

Scan QR to view Datasheet Catalog #    MBS428449 AKAP9 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AKAP9 / AKAP450 / CG-NAP, Peptide

 Also Known As   

AKAP9 / AKAP450 / CG-NAP Immunizing Peptide

 Product Synonym Names    AKAP9; CG-NAP; PRKA9; YOTIAO; AKAP350; HYPERION; KIAA0803; A kinase (PRKA) anchor protein (yotiao) 9; AKAP120-like protein; kinase N-associated protein; A-kinase anchoring protein 450; A-kinase anchor protein, 350kDa; protein kinase A anchoring protein 9; AKAP9 / AKAP450 / CG-NAP
 Product Gene Name   

AKAP9 peptide

[Similar Products]
 Product Synonym Gene Name    AKAP450; CG-NAP [Similar Products]
 Antibody/Peptide Pairs    AKAP9 / AKAP450 / CG-NAP peptide (MBS428449) is used for blocking the activity of AKAP9/AKAP450/CG-NAP antibody (MBS420313)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-SGSTTQFH AGMR
 OMIM    604001
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 Species Reactivity    Human, Mouse
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of AKAP9 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for AKAP9. It may not necessarily be applicable to this product.
 NCBI GI #    22538387
 NCBI GeneID    10142
 NCBI Accession #    NP_005742.4 [Other Products]
 NCBI Related Accession #    NP_671714.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005751.4 [Other Products]
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 UniProt Secondary Accession #    O14869; O43355; O94895; Q75N20; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2; A4D1F0; A4D1F2; A4D1F4 [Other Products]
 UniProt Related Accession #    Q99996 [Other Products]
 Molecular Weight    455,423 Da
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 NCBI Official Full Name    A-kinase anchor protein 9 isoform 2
 NCBI Official Synonym Full Names    A-kinase anchoring protein 9
 NCBI Official Symbol    AKAP9 [Similar Products]
 NCBI Official Synonym Symbols   
LQT11; PRKA9; AKAP-9; CG-NAP; YOTIAO; AKAP350; AKAP450; PPP1R45; HYPERION; MU-RMS-40.16A
[Similar Products]
 NCBI Protein Information    A-kinase anchor protein 9
 UniProt Protein Name    A-kinase anchor protein 9
 UniProt Synonym Protein Names   
A-kinase anchor protein 350 kDa; AKAP 350; hgAKAP 350; A-kinase anchor protein 450 kDa; AKAP 450; AKAP 120-like protein; Centrosome- and Golgi-localized PKN-associated protein
 Protein Family    A-kinase anchor protein
 UniProt Gene Name    AKAP9 [Similar Products]
 UniProt Synonym Gene Names    AKAP350; AKAP450; KIAA0803; PRKA9 [Similar Products]
 UniProt Entry Name    AKAP9_HUMAN
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 NCBI Summary for AKAP9    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]
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 UniProt Comments for AKAP9    AKAP9: Binds to type II regulatory subunits of protein kinase A. Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. May be required to maintain the integrity of the Golgi apparatus. Isoform 4 is associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations. Defects in AKAP9 are the cause of long QT syndrome type 11 (LQT11). Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress. They can present with a sentinel event of sudden cardiac death in infancy. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: centrosome; cis-Golgi network; cytoskeleton; cytosol; Golgi apparatus; Golgi stack; intracellular membrane-bound organelle; voltage-gated potassium channel complex

Molecular Function: potassium channel regulator activity; protein binding; protein complex scaffold; Ras guanyl-nucleotide exchange factor activity; receptor binding

Biological Process: G2/M transition of mitotic cell cycle; MAPKKK cascade; microtubule nucleation; positive regulation of GTPase activity; positive regulation of peptidyl-serine phosphorylation; signal transduction; synaptic transmission; transport

Disease: Long Qt Syndrome 11
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 Research Articles on AKAP9    1. Study suggests a role of rare missense variants at NRXN1 and AKAP9 in schizophrenia susceptibility, probably related to alteration of the excitatory/inhibitory synaptic balance, deserving further investigation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with AKAP9 peptidePathways associated with AKAP9 peptide
 Reference Product  PubMed Publications
 KCNQ1 peptide  >19 publications with AKAP9 and KCNQ1
 TUBGCP2 peptide  >1 publications with AKAP9 and TUBGCP2
 TUBGCP3 peptide  >1 publications with AKAP9 and TUBGCP3
 PRKAR2A peptide  >1 publications with AKAP9 and PRKAR2A
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 AURKA Activation By TPX2 Pathway antibodies  AURKA Activation By TPX2 Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CREB Phosphorylation Through The Activation Of CaMKII Pathway antibodies  CREB Phosphorylation Through The Activation Of CaMKII Pathway Diagram
 CREB Phosphorylation Through The Activation Of Ras Pathway antibodies  CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
 Cardiac Conduction Pathway antibodies  Cardiac Conduction Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with AKAP9 peptideOrgans/Tissues associated with AKAP9 peptide
 Disease Name  Pubmed Publications
 Death Antibodies  >10 publications with AKAP9 and Death
 Skin Diseases Antibodies  >5 publications with AKAP9 and Skin Diseases
 Breast Neoplasms Antibodies  >4 publications with AKAP9 and Breast Neoplasms
 Nervous System Diseases Antibodies  >4 publications with AKAP9 and Nervous System Diseases
 Brain Diseases Antibodies  >3 publications with AKAP9 and Brain Diseases
 Neoplasm Invasiveness Antibodies  >3 publications with AKAP9 and Neoplasm Invasiveness
 Adenocarcinoma Antibodies  >3 publications with AKAP9 and Adenocarcinoma
 Ovarian Neoplasms Antibodies  >2 publications with AKAP9 and Ovarian Neoplasms
 Fibrosis Antibodies  >2 publications with AKAP9 and Fibrosis
 Inflammation Antibodies  >2 publications with AKAP9 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >20 publications with AKAP9 and Heart
 Brain Antibodies  >15 publications with AKAP9 and Brain
 Muscle Antibodies  >14 publications with AKAP9 and Muscle
 Blood Antibodies  >11 publications with AKAP9 and Blood
 Thyroid Antibodies  >10 publications with AKAP9 and Thyroid
 Lung Antibodies  >8 publications with AKAP9 and Lung
 Nerve Antibodies  >7 publications with AKAP9 and Nerve
 Kidney Antibodies  >4 publications with AKAP9 and Kidney
 Eye Antibodies  >4 publications with AKAP9 and Eye
 Lymph Antibodies  >4 publications with AKAP9 and Lymph
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