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AKR1B10 peptide

Scan QR to view Datasheet Catalog #    MBS425906 AKR1B10 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AKR1B10, Peptide

 Also Known As   

AKR1B10 Immunizing Peptide

 Product Synonym Names    AKR1B10; aldo-keto reductase family 1, member B10 (aldose reductase); AKR1B11; AKR1B12; ALDRLn; ARL-1; ARL1; HIS; HIS; MGC14103; aldo-keto reductase family 1, member B10; aldo-keto reductase family 1, member B11 (aldose reductase-like); aldose reductase
 Product Gene Name   

AKR1B10 peptide

[Similar Products]
 Antibody/Peptide Pairs    AKR1B10 peptide (MBS425906) is used for blocking the activity of AKR1B10 antibody (MBS421176)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-QSSHLEDY PFDAE
 OMIM    604707
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of AKR1B10 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for AKR1B10. It may not necessarily be applicable to this product.
 NCBI GI #    20127592
 NCBI GeneID    57016
 NCBI Accession #    NP_064695.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_020299.3 [Other Products]
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 UniProt Secondary Accession #    O75890; Q6FHF3; Q8IWZ1; A4D1P1 [Other Products]
 UniProt Related Accession #    O60218 [Other Products]
 Molecular Weight    36,020 Da
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 NCBI Official Full Name    aldo-keto reductase family 1, member B10
 NCBI Official Synonym Full Names    aldo-keto reductase family 1, member B10 (aldose reductase)
 NCBI Official Symbol    AKR1B10 [Similar Products]
 NCBI Official Synonym Symbols   
HIS; HSI; ARL1; ARL-1; ALDRLn; AKR1B11; AKR1B12
[Similar Products]
 NCBI Protein Information    aldo-keto reductase family 1 member B10
 UniProt Protein Name    Aldo-keto reductase family 1 member B10
 UniProt Synonym Protein Names   
ARL-1; Aldose reductase-like; Aldose reductase-related protein; ARP; hARP; Small intestine reductase; SI reductase
 Protein Family    Aldo-keto reductase family
 UniProt Gene Name    AKR1B10 [Similar Products]
 UniProt Synonym Gene Names    AKR1B11; ARP; hARP; SI reductase [Similar Products]
 UniProt Entry Name    AK1BA_HUMAN
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 NCBI Summary for AKR1B10    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for AKR1B10    AKR1B10: Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. Belongs to the aldo/keto reductase family.

Protein type: EC 1.1.1.21; Carbohydrate Metabolism - fructose and mannose; Oxidoreductase; EC 1.1.1.-; Lipid Metabolism - linoleic acid; Carbohydrate Metabolism - butanoate

Chromosomal Location of Human Ortholog: 7q33

Cellular Component: cytosol; lysosome

Molecular Function: aldo-keto reductase activity; geranylgeranyl reductase activity; indanol dehydrogenase activity; protein binding; retinal dehydrogenase activity

Biological Process: aldehyde metabolic process; digestion; farnesol catabolic process; retinoid metabolic process; steroid metabolic process
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 Research Articles on AKR1B10    1. It would appear that hepatitis C virus infection alone increases AKR1B10 expression, which manifests itself as enhanced urinary excretion of polyols with reduced urinary excretion of their corresponding hexoses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AKR1B10 peptideDiseases associated with AKR1B10 peptide
 Products by Pathway  Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Fructose And Mannose Metabolism Pathway antibodies  Fructose And Mannose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Galactose Metabolism Pathway antibodies  Galactose Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Fat-soluble Vitamins Pathway antibodies  Metabolism Of Fat-soluble Vitamins Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >59 publications with AKR1B10 and Carcinoma
 Adenocarcinoma Antibodies  >39 publications with AKR1B10 and Adenocarcinoma
 Carcinoma, Hepatocellular Antibodies  >29 publications with AKR1B10 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >27 publications with AKR1B10 and Liver Neoplasms
 Liver Diseases Antibodies  >27 publications with AKR1B10 and Liver Diseases
 Lung Neoplasms Antibodies  >24 publications with AKR1B10 and Lung Neoplasms
 Breast Neoplasms Antibodies  >11 publications with AKR1B10 and Breast Neoplasms
 Inflammation Antibodies  >10 publications with AKR1B10 and Inflammation
 Colorectal Neoplasms Antibodies  >10 publications with AKR1B10 and Colorectal Neoplasms
 Neoplasms, Experimental Antibodies  >8 publications with AKR1B10 and Neoplasms, Experimental
Organs/Tissues associated with AKR1B10 peptide
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >44 publications with AKR1B10 and Liver
 Lung Antibodies  >41 publications with AKR1B10 and Lung
 Intestine Antibodies  >10 publications with AKR1B10 and Intestine
 Stomach Antibodies  >6 publications with AKR1B10 and Stomach
 Skin Antibodies  >6 publications with AKR1B10 and Skin
 Uterus Antibodies  >4 publications with AKR1B10 and Uterus
 Kidney Antibodies  >4 publications with AKR1B10 and Kidney
 Eye Antibodies  >3 publications with AKR1B10 and Eye
 Brain Antibodies  >3 publications with AKR1B10 and Brain
 Esophagus Antibodies  >2 publications with AKR1B10 and Esophagus
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