Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Peptide rightarrow CENTD3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Follicle Stimulating Hormone (FSH) ELISA Kit
 • TOP2A Antibody
 • Platelet Derived Growth Factor-BB (mPDGF BB) Recombinant Protein
 • NT-proBNP ELISA Kit
 • IRAK4 Antibody
 • Resistin (RETN) Recombinant Protein
 • A Disintegrin and Metalloproteinase With Thrombospondin 1 (A... ELISA Kit
 • Chymase 1, Mast Cell (CMA1) ELISA Kit
 • H7 (A-Netherlands-219-03)(H7N7 ) Antibody
 • Fibrinogen (FGG) ELISA Kit
 • Myelin P2 (PMP2) Recombinant Protein
 • IFI27 Antibody
 • Human IgA1 protein Immunoglobulin
 • Caspase 9 (CASP9) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

CENTD3 peptide :: ARAP3 Peptide

Scan QR to view Datasheet Catalog #    MBS426755 CENTD3 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ARAP3 (CENTD3), Peptide

 Also Known As   

ARAP3 Immunizing Peptide

 Product Synonym Names    CENTD3; centaurin, delta 3; ARAP3; FLJ21065; ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3; PtdIns(3,4,5)P3-binding protein; phosphoinositide binding protein; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
 Product Gene Name   

CENTD3 peptide

[Similar Products]
 Product Synonym Gene Name    ARAP3 [Similar Products]
 Antibody/Peptide Pairs    ARAP3 peptide (MBS426755) is used for blocking the activity of ARAP3 antibody (MBS421192)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    CTSSPPSSQP LT
 OMIM    606647
Section Bar
 Species Reactivity    Human, Mouse, Dog, Pig, Cow
Section Bar
 Form/Format    100ug of dried peptide
Section Bar
Section Bar
 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of CENTD3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CENTD3. It may not necessarily be applicable to this product.
 NCBI GI #    21264337
 NCBI GeneID    64411
 NCBI Accession #    NP_071926.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_022481.5 [Other Products]
Section Bar
 UniProt Secondary Accession #    B4DIT1; D3DQE3 [Other Products]
 UniProt Related Accession #    Q8WWN8 [Other Products]
 Molecular Weight    131,986 Da
Table BarTOPTable Bar
 NCBI Official Full Name    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 NCBI Official Synonym Full Names    ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
 NCBI Official Symbol    ARAP3 [Similar Products]
 NCBI Official Synonym Symbols   
DRAG1; CENTD3
[Similar Products]
 NCBI Protein Information    arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 UniProt Protein Name    Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 UniProt Synonym Protein Names   
Centaurin-delta-3; Cnt-d3
 UniProt Gene Name    ARAP3 [Similar Products]
 UniProt Synonym Gene Names    CENTD3; Cnt-d3 [Similar Products]
 UniProt Entry Name    ARAP3_HUMAN
Section Bar
 NCBI Summary for CENTD3    This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015]
Section Bar
 UniProt Comments for CENTD3    ARAP3: Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin.

Protein type: Motility/polarity/chemotaxis; GAPs, ARF; GAPs

Chromosomal Location of Human Ortholog: 5q31.3

Cellular Component: cytoplasm; cytoskeleton; cytosol; lamellipodium; plasma membrane; ruffle

Molecular Function: GTPase activator activity; metal ion binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding

Biological Process: cytoskeleton organization and biogenesis; negative regulation of cell migration; negative regulation of Rac protein signal transduction; negative regulation of Rho protein signal transduction; positive regulation of GTPase activity; regulation of cell shape; regulation of small GTPase mediated signal transduction; signal transduction; vesicle-mediated transport
Table BarTOPTable Bar
 Research Articles on CENTD3    1. structural and binding affinity between odin and arap3
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with CENTD3 peptidePathways associated with CENTD3 peptide
 Reference Product  PubMed Publications
 RHOA peptide  >17 publications with CENTD3 and RHOA
 ARF6 peptide  >13 publications with CENTD3 and ARF6
 CDC42 peptide  >2 publications with CENTD3 and CDC42
 VAV1 peptide  >1 publications with CENTD3 and VAV1
 VAV2 peptide  >1 publications with CENTD3 and VAV2
 Products by Pathway  Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Rap1 Signaling Pathway antibodies  Rap1 Signaling Pathway Diagram
 Regulation Of RhoA Activity Pathway antibodies  Regulation Of RhoA Activity Pathway Diagram
 Rho GTPase Cycle Pathway antibodies  Rho GTPase Cycle Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Rho GTPases Pathway antibodies  Signaling By Rho GTPases Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
Diseases associated with CENTD3 peptideOrgans/Tissues associated with CENTD3 peptide
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >4 publications with CENTD3 and Inflammation
 Neoplasm Metastasis Antibodies  >2 publications with CENTD3 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >2 publications with CENTD3 and Disease Models, Animal
 Neoplasm Invasiveness Antibodies  >1 publications with CENTD3 and Neoplasm Invasiveness
 Adenocarcinoma Antibodies  >1 publications with CENTD3 and Adenocarcinoma
 Respiratory Tract Diseases Antibodies  >1 publications with CENTD3 and Respiratory Tract Diseases
 Lung Injury Antibodies  >1 publications with CENTD3 and Lung Injury
 Fibrosis Antibodies  >1 publications with CENTD3 and Fibrosis
 Edema Antibodies  >1 publications with CENTD3 and Edema
 Lung Diseases Antibodies  >1 publications with CENTD3 and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with CENTD3 and Bone
 Vascular Antibodies  >2 publications with CENTD3 and Vascular
 Bone Marrow Antibodies  >2 publications with CENTD3 and Bone Marrow
 Stomach Antibodies  >1 publications with CENTD3 and Stomach
 Pancreas Antibodies  >1 publications with CENTD3 and Pancreas
 Heart Antibodies  >1 publications with CENTD3 and Heart
 Lung Antibodies  >1 publications with CENTD3 and Lung
 Embryonic Tissue Antibodies  >1 publications with CENTD3 and Embryonic Tissue
 Brain Antibodies  >1 publications with CENTD3 and Brain
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions