Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Peptide rightarrow ACVRL1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • ADH7 Peptide
 • T-complex Protein 1 epsilon (CCT5) Antibody
 • transient receptor potential cation channel, subfamily V, me... ELISA Kit
 • JAB-1 Antibody
 • Elastase 3A (ELA3A) Recombinant Protein
 • Corticoliberin (Crh) ELISA Kit
 • TLR9 Antibody
 • MTCO1 (MT-CO1) Antibody
 • inositol polyphosphate-5-phosphatase (INPP5D) Antibody
 • C-type lectin domain family 18 member A (CLEC18A) Recombinant Protein
 • RFC4 Antibody
 • phosphorylated microtubule Associated protein tau (pMAPT-pTA... ELISA Kit
 • Malaria Pv mAb1-labeling Antibody
 • Na+-H+ EXCHANGER-1 (SLC9A1) Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

ACVRL1 peptide :: Activin receptor-like kinase 1 Peptide

Scan QR to view Datasheet Catalog #    MBS425741 ACVRL1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Activin receptor-like kinase 1 (ACVRL1), Peptide

 Also Known As   

Activin receptor-like kinase 1 Immunizing Peptide

 Product Synonym Names    ACVRL1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; ACVRLK1; activin A receptor type II-like 1; Activin A receptor, type II-like kinase 1; ALK1; TSR-I; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1; serine/threonine-protein kinase r; Activin receptor-like kinase 1; Activin receptor-like kinase 1
 Product Gene Name   

ACVRL1 peptide

[Similar Products]
 Antibody/Peptide Pairs    Activin receptor-like kinase 1 peptide (MBS425741) is used for blocking the activity of Activin receptor-like kinase 1 antibody (MBS421383)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Sequence    C-KISNSPEK PKVIQ
 OMIM    600376
Section Bar
 Species Reactivity    Human
Section Bar
 Form/Format    100ug of dried peptide
Section Bar
Section Bar
 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of ACVRL1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ACVRL1. It may not necessarily be applicable to this product.
 NCBI GI #    116734712
 NCBI GeneID    94
 NCBI Accession #    NP_000011.2 [Other Products]
 NCBI Related Accession #    NP_001070869.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000020.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    A6NGA8 [Other Products]
 UniProt Related Accession #    P37023 [Other Products]
 Molecular Weight    56,124 Da
Table BarTOPTable Bar
 NCBI Official Full Name    serine/threonine-protein kinase receptor R3
 NCBI Official Synonym Full Names    activin A receptor like type 1
 NCBI Official Symbol    ACVRL1 [Similar Products]
 NCBI Official Synonym Symbols   
HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase receptor R3
 UniProt Protein Name    Serine/threonine-protein kinase receptor R3
 UniProt Synonym Protein Names   
Activin receptor-like kinase 1; ALK-1; TGF-B superfamily receptor type I; TSR-I
 Protein Family    Serine/threonine-protein kinase receptor
 UniProt Gene Name    ACVRL1 [Similar Products]
 UniProt Synonym Gene Names    ACVRLK1; ALK1; SKR3; ALK-1; TSR-I [Similar Products]
 UniProt Entry Name    ACVL1_HUMAN
Section Bar
 NCBI Summary for ACVRL1    This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for ACVRL1    ALK1: a kinase of the STKR family. A type I cell-surface receptor for the TGF-beta superfamily of ligands including Activin A. Highly expressed in human placenta and lung. Deficiency causes hemorrhagic telangiectasia type 2 also known as Rendu-Osler-Weber syndrome 2.

Protein type: Membrane protein, integral; Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (receptor); EC 2.7.11.30; TKL group; STKR family; Type1 subfamily

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cell soma; cell surface; dendrite; integral to plasma membrane; plasma membrane

Molecular Function: activin binding; activin receptor activity, type I; ATP binding; metal ion binding; protein binding; protein kinase binding; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; SMAD binding; transforming growth factor beta binding; transforming growth factor beta receptor activity; transforming growth factor beta receptor activity, type I; transmembrane receptor protein serine/threonine kinase activity

Biological Process: activin receptor signaling pathway; angiogenesis; blood circulation; blood vessel endothelial cell proliferation during sprouting angiogenesis; blood vessel maturation; blood vessel remodeling; BMP signaling pathway; in utero embryonic development; lymphangiogenesis; negative regulation of blood vessel endothelial cell migration; negative regulation of cell adhesion; negative regulation of cell growth; negative regulation of cell migration; negative regulation of cell proliferation; negative regulation of endothelial cell differentiation; negative regulation of endothelial cell proliferation; negative regulation of focal adhesion formation; positive regulation of angiogenesis; positive regulation of BMP signaling pathway; positive regulation of chondrocyte differentiation; positive regulation of endothelial cell differentiation; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid phosphorylation; protein heterooligomerization; regulation of blood pressure; regulation of blood vessel endothelial cell migration; regulation of DNA replication; regulation of endothelial cell proliferation; regulation of transcription, DNA-dependent; signal transduction; transforming growth factor beta receptor signaling pathway; wound healing, spreading of epidermal cells

Disease: Telangiectasia, Hereditary Hemorrhagic, Type 2
Table BarTOPTable Bar
 Research Articles on ACVRL1    1. This work was designed to examine the pathogenicity of 23 nucleotide variations in ACVRL1 gene detected in more than 400 Hereditary Hemorrhagic Telangiectasia syndrome patients.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with ACVRL1 peptidePathways associated with ACVRL1 peptide
 Reference Product  PubMed Publications
 ENG peptide  >209 publications with ACVRL1 and ENG
 SMAD1 peptide  >61 publications with ACVRL1 and SMAD1
 TGFB1 peptide  >48 publications with ACVRL1 and TGFB1
 SMAD5 peptide  >21 publications with ACVRL1 and SMAD5
 TGFBR2 peptide  >9 publications with ACVRL1 and TGFBR2
 SMAD9 peptide  >6 publications with ACVRL1 and SMAD9
 ACVR2B peptide  >2 publications with ACVRL1 and ACVR2B
 TGFB3 peptide  >1 publications with ACVRL1 and TGFB3
 ACVR2A peptide  >1 publications with ACVRL1 and ACVR2A
 Products by Pathway  Pathway Diagram
 ALK1 Pathway antibodies  ALK1 Pathway Diagram
 ALK1 Signaling Events Pathway antibodies  ALK1 Signaling Events Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
Diseases associated with ACVRL1 peptideOrgans/Tissues associated with ACVRL1 peptide
 Disease Name  Pubmed Publications
 Telangiectasia, Hereditary Hemorrhagic Antibodies  >225 publications with ACVRL1 and Telangiectasia, Hereditary Hemorrhagic
 Cardiovascular Diseases Antibodies  >218 publications with ACVRL1 and Cardiovascular Diseases
 Hypertension Antibodies  >65 publications with ACVRL1 and Hypertension
 Lung Diseases Antibodies  >61 publications with ACVRL1 and Lung Diseases
 Heart Diseases Antibodies  >24 publications with ACVRL1 and Heart Diseases
 Fibrosis Antibodies  >15 publications with ACVRL1 and Fibrosis
 Inflammation Antibodies  >15 publications with ACVRL1 and Inflammation
 Liver Diseases Antibodies  >11 publications with ACVRL1 and Liver Diseases
 Lung Neoplasms Antibodies  >10 publications with ACVRL1 and Lung Neoplasms
 Breast Neoplasms Antibodies  >9 publications with ACVRL1 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >260 publications with ACVRL1 and Vascular
 Bone Antibodies  >109 publications with ACVRL1 and Bone
 Brain Antibodies  >61 publications with ACVRL1 and Brain
 Lung Antibodies  >59 publications with ACVRL1 and Lung
 Heart Antibodies  >50 publications with ACVRL1 and Heart
 Muscle Antibodies  >43 publications with ACVRL1 and Muscle
 Liver Antibodies  >43 publications with ACVRL1 and Liver
 Skin Antibodies  >33 publications with ACVRL1 and Skin
 Kidney Antibodies  >15 publications with ACVRL1 and Kidney
 Connective Tissue Antibodies  >9 publications with ACVRL1 and Connective Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions