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BLK peptide

Scan QR to view Datasheet Catalog #    MBS427526 BLK peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

BLK, Peptide

 Also Known As   

BLK Immunizing Peptide

 Product Synonym Names    BLK; B lymphoid tyrosine kinase; MGC10442; MODY11; BLK nonreceptor tyrosine kinase; b lymphocyte kinase; p55-Blk; tyrosine-protein kinase Blk
 Product Gene Name   

BLK peptide

[Similar Products]
 Antibody/Peptide Pairs    BLK peptide (MBS427526) is used for blocking the activity of BLK antibody (MBS422608)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    QWSPLKVSAQ DKD-C
 OMIM    191305
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of BLK peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for BLK. It may not necessarily be applicable to this product.
 NCBI GI #    33469982
 NCBI GeneID    640
 NCBI Accession #    NP_001706.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001715.2 [Other Products]
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 UniProt Secondary Accession #    Q16291; Q96IN1 [Other Products]
 UniProt Related Accession #    P51451 [Other Products]
 Molecular Weight    57,706 Da
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 NCBI Official Full Name    tyrosine-protein kinase Blk
 NCBI Official Synonym Full Names    BLK proto-oncogene, Src family tyrosine kinase
 NCBI Official Symbol    BLK [Similar Products]
 NCBI Official Synonym Symbols   
MODY11
[Similar Products]
 NCBI Protein Information    tyrosine-protein kinase Blk
 UniProt Protein Name    Tyrosine-protein kinase Blk
 UniProt Synonym Protein Names   
B lymphocyte kinase; p55-Blk
 Protein Family    Tyrosine-protein kinase
 UniProt Gene Name    BLK [Similar Products]
 UniProt Entry Name    BLK_HUMAN
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 NCBI Summary for BLK    This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]
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 UniProt Comments for BLK    BLK: a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes

Protein type: Kinase, protein; Protein kinase, tyrosine (non-receptor); Protein kinase, TK; EC 2.7.10.2; TK group; Src family

Chromosomal Location of Human Ortholog: 8p23-p22

Cellular Component: extrinsic to internal side of plasma membrane

Molecular Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor binding

Biological Process: B cell receptor signaling pathway; cell differentiation; cytoskeleton organization and biogenesis; innate immune response; negative regulation of apoptosis; positive regulation of insulin secretion; regulation of cell proliferation; regulation of phagocytosis; transmembrane receptor protein tyrosine kinase signaling pathway

Disease: Maturity-onset Diabetes Of The Young, Type 11
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 Research Articles on BLK    1. Report a novel BLK gene variant in common variable immunodeficiency-patients that causes suppressed B-cell proliferation and reduced ability of B-cells to elicit antigen-specific CD4(+) T-cell responses.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with BLK peptidePathways associated with BLK peptide
 Reference Product  PubMed Publications
 CD79B peptide  >5 publications with BLK and CD79B
 CD79A peptide  >5 publications with BLK and CD79A
 EGFR peptide  >4 publications with BLK and EGFR
 PLCG2 peptide  >2 publications with BLK and PLCG2
 CBL peptide  >2 publications with BLK and CBL
 STAT3 peptide  >1 publications with BLK and STAT3
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Alpha-synuclein Signaling Pathway antibodies  Alpha-synuclein Signaling Pathway Diagram
 Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway antibodies  Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
 EPHA Forward Signaling Pathway antibodies  EPHA Forward Signaling Pathway Diagram
 Ephrin B Reverse Signaling Pathway antibodies  Ephrin B Reverse Signaling Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
Diseases associated with BLK peptideOrgans/Tissues associated with BLK peptide
 Disease Name  Pubmed Publications
 Lupus Erythematosus, Systemic Antibodies  >59 publications with BLK and Lupus Erythematosus, Systemic
 Nervous System Diseases Antibodies  >30 publications with BLK and Nervous System Diseases
 Arthritis, Rheumatoid Antibodies  >26 publications with BLK and Arthritis, Rheumatoid
 Cardiovascular Diseases Antibodies  >25 publications with BLK and Cardiovascular Diseases
 Brain Diseases Antibodies  >23 publications with BLK and Brain Diseases
 Leukemia Antibodies  >22 publications with BLK and Leukemia
 Inflammation Antibodies  >19 publications with BLK and Inflammation
 Necrosis Antibodies  >16 publications with BLK and Necrosis
 Lung Diseases Antibodies  >9 publications with BLK and Lung Diseases
 Kidney Diseases Antibodies  >9 publications with BLK and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >157 publications with BLK and Blood
 Spleen Antibodies  >17 publications with BLK and Spleen
 Lung Antibodies  >16 publications with BLK and Lung
 Bone Marrow Antibodies  >14 publications with BLK and Bone Marrow
 Lymph Node Antibodies  >12 publications with BLK and Lymph Node
 Lymph Antibodies  >12 publications with BLK and Lymph
 Intestine Antibodies  >6 publications with BLK and Intestine
 Thymus Antibodies  >5 publications with BLK and Thymus
 Pancreas Antibodies  >4 publications with BLK and Pancreas
 Connective Tissue Antibodies  >3 publications with BLK and Connective Tissue
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