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CABP1 peptide

Scan QR to view Datasheet Catalog #    MBS425546 CABP1 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CABP1, Peptide

 Also Known As   

CABP1 Immunizing Peptide

 Product Synonym Names    CABP1; CALBRAIN; HCALB_BR; calcium binding protein 1 (calbrain); calbrain; calcium binding protein 5; calcium binding protein 1 calbrain; caldendrin
 Product Gene Name   

CABP1 peptide

[Similar Products]
 Antibody/Peptide Pairs    CABP1 peptide (MBS425546) is used for blocking the activity of CABP1 antibody (MBS420126)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    GNCVKYPLRN LS
 OMIM    605563
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 Species Reactivity    Human
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of CABP1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CABP1. It may not necessarily be applicable to this product.
 NCBI GI #    13929432
 NCBI GeneID    9478
 NCBI Accession #    NP_112482.1 [Other Products]
 NCBI Related Accession #    NP_004267.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_031205.3 [Other Products]
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 UniProt Secondary Accession #    O95663; Q8N6H5; Q9NZU8 [Other Products]
 UniProt Related Accession #    Q9NZU7 [Other Products]
 Molecular Weight    8,139 Da
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 NCBI Official Full Name    calcium-binding protein 1 isoform 1
 NCBI Official Synonym Full Names    calcium binding protein 1
 NCBI Official Symbol    CABP1 [Similar Products]
 NCBI Official Synonym Symbols   
CALBRAIN; HCALB_BR
[Similar Products]
 NCBI Protein Information    calcium-binding protein 1
 UniProt Protein Name    Calcium-binding protein 1
 UniProt Synonym Protein Names   
Calbrain; Caldendrin
 Protein Family    Calcium-binding protein
 UniProt Gene Name    CABP1 [Similar Products]
 UniProt Synonym Gene Names    CaBP1 [Similar Products]
 UniProt Entry Name    CABP1_HUMAN
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 NCBI Summary for CABP1    Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]
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 UniProt Comments for CABP1    CABP1: Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor- induced cellular degeneration. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding; Inhibitor; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: cell cortex; cell junction; cytoskeleton; extracellular space; Golgi membrane; perinuclear region of cytoplasm; plasma membrane; postsynaptic density; postsynaptic membrane

Molecular Function: calcium ion binding; calcium-dependent protein binding; enzyme inhibitor activity; nuclear localization sequence binding; protein binding

Biological Process: negative regulation of catalytic activity; negative regulation of protein import into nucleus
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 Research Articles on CABP1    1. the faster migrating Tg adduct C primarily engages the CaBP1/P5 oxidoreductase, whereas the slower migrating Tg adduct A primarily engages ERp72.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CABP1 peptideDiseases associated with CABP1 peptide
 Reference Product  PubMed Publications
 ITPR1 peptide  >3 publications with CABP1 and ITPR1
 MYO1C peptide  >1 publications with CABP1 and MYO1C
 Disease Name  Pubmed Publications
 Poisoning Antibodies  >2 publications with CABP1 and Poisoning
 Inflammation Antibodies  >2 publications with CABP1 and Inflammation
 Liver Diseases Antibodies  >1 publications with CABP1 and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with CABP1 and Kidney Diseases
 Hyperplasia Antibodies  >1 publications with CABP1 and Hyperplasia
 Hemorrhage Antibodies  >1 publications with CABP1 and Hemorrhage
 Acute Kidney Injury Antibodies  >1 publications with CABP1 and Acute Kidney Injury
 Drug-Induced Liver Injury Antibodies  >1 publications with CABP1 and Drug-Induced Liver Injury
 Weight Loss Antibodies  >1 publications with CABP1 and Weight Loss
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with CABP1 and Drug-Related Side Effects and Adverse Reactions
Organs/Tissues associated with CABP1 peptide
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >32 publications with CABP1 and Brain
 Eye Antibodies  >8 publications with CABP1 and Eye
 Kidney Antibodies  >3 publications with CABP1 and Kidney
 Testis Antibodies  >2 publications with CABP1 and Testis
 Lung Antibodies  >1 publications with CABP1 and Lung
 Pineal Gland Antibodies  >1 publications with CABP1 and Pineal Gland
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