NP_004582.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,691 Da
NCBI Official Full Name
C-C motif chemokine 20 isoform 1
NCBI Official Synonym Full Names
C-C motif chemokine ligand 20
NCBI Official Synonym Symbols
CKb4; LARC; ST38; MIP3A; Exodus; MIP-3a; SCYA20; MIP-3-alpha [Similar Products]
NCBI Protein Information
C-C motif chemokine 20
UniProt Protein Name
C-C motif chemokine 20
UniProt Synonym Protein Names
Beta-chemokine exodus-1; CC chemokine LARC; Liver and activation-regulated chemokine; Macrophage inflammatory protein 3 alpha; MIP-3-alpha
UniProt Synonym Gene Names
UniProt Entry Name
CCL20_HUMAN
NCBI Summary for CCL20
This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
UniProt Comments for CCL20
CCL20: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli 25922 and S.aureus 29213. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Chemokine; Motility/polarity/chemotaxis; Secreted
Chromosomal Location of Human Ortholog: 2q36.3
Cellular Component: extracellular region; extracellular space
Molecular Function: CCR chemokine receptor binding; chemokine activity; protein binding
Biological Process: cell-cell signaling; chemotaxis; defense response to bacterium; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; lymphocyte chemotaxis; monocyte chemotaxis; neutrophil chemotaxis; positive regulation of GTPase activity; positive regulation of interleukin-1 alpha biosynthetic process; positive regulation of nitric-oxide synthase biosynthetic process; signal transduction; wound healing
Research Articles on CCL20
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Products associated with CCL20 blocking peptide
Pathways associated with CCL20 blocking peptide
Diseases associated with CCL20 blocking peptide
Organs/Tissues associated with CCL20 blocking peptide
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