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CSK peptide

Scan QR to view Datasheet Catalog #    MBS425187 CSK peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CSK, Peptide

 Also Known As   

CSK Immunizing Peptide

 Product Synonym Names    CSK; c-src tyrosine kinase; MGC117393
 Product Gene Name   

CSK peptide

[Similar Products]
 Antibody/Peptide Pairs    CSK peptide (MBS425187) is used for blocking the activity of CSK antibody (MBS421145)
 Antibody/Peptide Pairs    CSK peptide (MBS425187) is used for blocking the activity of CSK antibody (MBS423692)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-EQLEHIKT HELHL
 OMIM    124095
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of CSK peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CSK. It may not necessarily be applicable to this product.
 NCBI GI #    4758078
 NCBI GeneID    1445
 NCBI Accession #    NP_004374.1 [Other Products]
 NCBI Related Accession #    NP_001120662.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004383.2 [Other Products]
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 UniProt Secondary Accession #    Q2M3N2; Q6FGZ6 [Other Products]
 UniProt Related Accession #    P41240 [Other Products]
 Molecular Weight    50,704 Da
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 NCBI Official Full Name    tyrosine-protein kinase CSK
 NCBI Official Synonym Full Names    c-src tyrosine kinase
 NCBI Official Symbol    CSK [Similar Products]
 NCBI Protein Information    tyrosine-protein kinase CSK
 UniProt Protein Name    Tyrosine-protein kinase CSK
 UniProt Synonym Protein Names   
C-Src kinase; Protein-tyrosine kinase CYL
 Protein Family    Chloroplast sensor kinase
 UniProt Gene Name    CSK [Similar Products]
 UniProt Entry Name    CSK_HUMAN
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 UniProt Comments for CSK    CSK: a tyrosine kinase of the Csk family that phosphorylates and inhibits Src family kinases. Specifically phosphorylates Y504 on LCK, which acts as a negative regulatory site. Csk and the phospho-tyrosine phosphatase CD45 reciprocally regulate phosphorylation of the inhibitory tyrosine of the Src family kinases Lck and Fyn during T-cell receptor mediated signaling during thymic development.

Protein type: Kinase, protein; Protein kinase, TK; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); TK group; Csk family

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; intercellular junction; lipid raft; plasma membrane

Molecular Function: ATP binding; identical protein binding; kinase activity; metal ion binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein C-terminus binding; protein phosphatase binding; protein-tyrosine kinase activity; receptor binding

Biological Process: adaptive immune response; brain development; cell differentiation; cell migration; central nervous system development; epidermal growth factor receptor signaling pathway; innate immune response; negative regulation of bone resorption; negative regulation of cell proliferation; negative regulation of Golgi to plasma membrane protein transport; negative regulation of interleukin-6 production; negative regulation of kinase activity; negative regulation of phagocytosis; oligodendrocyte differentiation; positive regulation of MAP kinase activity; protein amino acid phosphorylation; regulation of cell proliferation; regulation of cytokine production; T cell costimulation; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway
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 Research Articles on CSK    1. Variant rs1378942 near CSK was nominally associated with systolic blood pressure in a Chinese population.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CSK peptidePathways associated with CSK peptide
 Reference Product  PubMed Publications
 SRC peptide  >1597 publications with CSK and SRC
 FYN peptide  >164 publications with CSK and FYN
 PAG1 peptide  >66 publications with CSK and PAG1
 PXN peptide  >27 publications with CSK and PXN
 AKT1 peptide  >19 publications with CSK and AKT1
 SHC1 peptide  >13 publications with CSK and SHC1
 DOK1 peptide  >9 publications with CSK and DOK1
 BCAR1 peptide  >8 publications with CSK and BCAR1
 CD247 peptide  >1 publications with CSK and CD247
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
Diseases associated with CSK peptideOrgans/Tissues associated with CSK peptide
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >223 publications with CSK and Inflammation
 Carcinoma Antibodies  >180 publications with CSK and Carcinoma
 Necrosis Antibodies  >135 publications with CSK and Necrosis
 Heart Diseases Antibodies  >114 publications with CSK and Heart Diseases
 Breast Neoplasms Antibodies  >102 publications with CSK and Breast Neoplasms
 Kidney Diseases Antibodies  >101 publications with CSK and Kidney Diseases
 Hypertension Antibodies  >81 publications with CSK and Hypertension
 Adenocarcinoma Antibodies  >71 publications with CSK and Adenocarcinoma
 Neoplasm Invasiveness Antibodies  >69 publications with CSK and Neoplasm Invasiveness
 Cell Transformation, Neoplastic Antibodies  >64 publications with CSK and Cell Transformation, Neoplastic
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >662 publications with CSK and Blood
 Vascular Antibodies  >218 publications with CSK and Vascular
 Brain Antibodies  >202 publications with CSK and Brain
 Bone Antibodies  >199 publications with CSK and Bone
 Kidney Antibodies  >184 publications with CSK and Kidney
 Lung Antibodies  >136 publications with CSK and Lung
 Heart Antibodies  >119 publications with CSK and Heart
 Liver Antibodies  >104 publications with CSK and Liver
 Bone Marrow Antibodies  >94 publications with CSK and Bone Marrow
 Skin Antibodies  >83 publications with CSK and Skin
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