Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Peptide rightarrow KCNIP3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CD79A Antibody
 • Group-Specific Component Globulin (GC) ELISA Kit
 • Pepsinogen C (PGC) ELISA Kit
 • Soluble Farnesoid X Receptor (FXR) ELISA Kit
 • Hyaluronan Binding Protein 1 (HABP1) ELISA Kit
 • Cytokeratin Fragment Antigen 21-1 (CYFRA21-1) ELISA Kit
 • Sterile Alpha Motif Domain-Containing 9-Like Protein (SAMD9L... ELISA Kit
 • Gap Junction Protein Beta 1 (GJB1) ELISA Kit
 • Cytochrome B5 (CYTB5) ELISA Kit
 • Intact Parathormone (I-PTH) ELISA Kit
 • Epiligrin ELISA Kit
 • Coagulation Factor 5 Antigen (F5-AG) ELISA Kit
 • Retinoblastoma Protein 1 (RB1) ELISA Kit
 • Dynorphin ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

KCNIP3 peptide :: Calsenilin Peptide

Scan QR to view Datasheet Catalog #    MBS843718 KCNIP3 peptide
Unit / Price
0.05 mg  /  $155 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calsenilin (KCNIP3), Peptide

 Also Known As   

Calsenilin Blocking Peptide

 Product Gene Name   

KCNIP3 peptide

[Similar Products]
 Antibody/Peptide Pairs    Calsenilin peptide (MBS843718) is used for blocking the activity of Calsenilin antibody (MBS840768)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    604662
 3D Structure    ModBase 3D Structure for Q9Y2W7
Section Bar
Section Bar
 Form/Format    50 ug (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1% BSA and 0.02% sodium azide.
Appearance: Colorless liquid
 Concentration    0.2 mg/ml (lot specific)
Section Bar
 Handling    The peptide solution should be gently mixed before use.
Section Bar
 Preparation and Storage    At -20 degree C
Shelf Life: 12 months
 Other Notes    Small volumes of KCNIP3 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for KCNIP3 peptide   

Western Blot (WB)

 Application Notes for KCNIP3 peptide    The peptide is used for blocking the antibody activity of Calsenilin. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37 degree C.
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for KCNIP3. It may not necessarily be applicable to this product.
 NCBI GI #    78190495
 NCBI GeneID    30818
 NCBI Accession #    NP_001030086.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001034914.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9Y2W7 [Other Products]
 UniProt Secondary Accession #    Q3YAC3; Q3YAC4; Q53TJ5; Q96T40; Q9UJ84; Q9UJ85; H7BY46 [Other Products]
 UniProt Related Accession #    Q9Y2W7 [Other Products]
 Molecular Weight    26,335 Da [Similar Products]
Table BarTOPTable Bar
 NCBI Official Full Name    calsenilin isoform 2
 NCBI Official Synonym Full Names    Kv channel interacting protein 3, calsenilin
 NCBI Official Symbol    KCNIP3 [Similar Products]
 NCBI Official Synonym Symbols   
CSEN; DREAM; KCHIP3
[Similar Products]
 NCBI Protein Information    calsenilin
 UniProt Protein Name    Calsenilin
 UniProt Synonym Protein Names   
A-type potassium channel modulatory protein 3; DRE-antagonist modulator; DREAM; Kv channel-interacting protein 3; KChIP3
 Protein Family    Calsenilin
 UniProt Gene Name    KCNIP3 [Similar Products]
 UniProt Synonym Gene Names    CSEN; DREAM; KCHIP3; DREAM; KChIP3 [Similar Products]
 UniProt Entry Name    CSEN_HUMAN
Section Bar
 NCBI Summary for KCNIP3    This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for KCNIP3    calsenilin: a small calcium-binding protein. Member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Modulates K4 voltage-gated potassium channels. May regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Also functions as a calcium-regulated transcriptional repressor, and to interact with presenilins. May play a role in the regulation of PSEN2 proteolytic processing.

Protein type: Transcription factor; Calcium-binding

Chromosomal Location of Human Ortholog: 2q21.1

Cellular Component: Golgi apparatus; voltage-gated potassium channel complex; endoplasmic reticulum; dendrite; nerve terminal; cytosol; nucleus

Molecular Function: protein C-terminus binding; potassium channel regulator activity; potassium channel activity; DNA binding; sequence-specific DNA binding; voltage-gated ion channel activity; calcium ion binding; calcium-dependent protein binding; transcription corepressor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; intracellular protein transport; behavioral response to pain; transcription, DNA-dependent; apoptosis; regulation of neuron apoptosis; negative regulation of transcription from RNA polymerase II promoter; signal transduction; sensory perception of pain
Table BarTOPTable Bar
 Research Articles on KCNIP3    1. Imatinib induces GIST cell quiescence in vivo and that this process also involves the DREAM complex.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with KCNIP3 peptidePathways associated with KCNIP3 peptide
 Reference Product  PubMed Publications
 PSEN2 peptide  >5 publications with KCNIP3 and PSEN2
 PSEN1 peptide  >4 publications with KCNIP3 and PSEN1
 KCND2 peptide  >2 publications with KCNIP3 and KCND2
 CREM peptide  >2 publications with KCNIP3 and CREM
 PDYN peptide  >1 publications with KCNIP3 and PDYN
 DPP10 peptide  >1 publications with KCNIP3 and DPP10
 Products by Pathway  Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 TSH Signaling Pathway antibodies  TSH Signaling Pathway Diagram
Diseases associated with KCNIP3 peptideOrgans/Tissues associated with KCNIP3 peptide
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >11 publications with KCNIP3 and Nervous System Diseases
 Mental Disorders Antibodies  >5 publications with KCNIP3 and Mental Disorders
 Dementia Antibodies  >5 publications with KCNIP3 and Dementia
 Epilepsy Antibodies  >3 publications with KCNIP3 and Epilepsy
 Edema Antibodies  >1 publications with KCNIP3 and Edema
 Hypertension Antibodies  >1 publications with KCNIP3 and Hypertension
 Seizures Antibodies  >1 publications with KCNIP3 and Seizures
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with KCNIP3 and Brain
 Thyroid Antibodies  >4 publications with KCNIP3 and Thyroid
 Kidney Antibodies  >2 publications with KCNIP3 and Kidney
 Placenta Antibodies  >1 publications with KCNIP3 and Placenta
 Eye Antibodies  >1 publications with KCNIP3 and Eye
 Thymus Antibodies  >1 publications with KCNIP3 and Thymus
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions