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CAT peptide :: Catalase / CAT Peptide

Scan QR to view Datasheet Catalog #    MBS426759 CAT peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Catalase / CAT, Peptide

 Also Known As   

Catalase / CAT Immunizing Peptide

 Product Synonym Names    CAT; catalase; HGNC: 1516; MGC138422; MGC138424; Catalase; Catalase / CAT
 Product Gene Name   

CAT peptide

[Similar Products]
 Antibody/Peptide Pairs    Catalase / CAT peptide (MBS426759) is used for blocking the activity of Catalase/CAT antibody (MBS421491)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-DKYNAEKP KNAIHT
 OMIM    115500
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 Species Reactivity    Human, Mouse, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of CAT peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for CAT. It may not necessarily be applicable to this product.
 NCBI GI #    4557014
 NCBI GeneID    847
 NCBI Accession #    NP_001743.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001752.3 [Other Products]
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 UniProt Secondary Accession #    Q2M1U4; Q4VXX5; Q9BWT9; Q9UC85; A8K6C0; B2RCZ9; D3DR07 [Other Products]
 UniProt Related Accession #    P04040 [Other Products]
 Molecular Weight    59,756 Da
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 NCBI Official Full Name    catalase
 NCBI Official Synonym Full Names    catalase
 NCBI Official Symbol    CAT [Similar Products]
 NCBI Protein Information    catalase
 UniProt Protein Name    Catalase
 UniProt Gene Name    CAT [Similar Products]
 UniProt Entry Name    CATA_HUMAN
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 NCBI Summary for CAT    This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]
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 UniProt Comments for CAT    Catalase: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. Homotetramer. Belongs to the catalase family.

Protein type: Hydrolase; Endoplasmic reticulum; Amino Acid Metabolism - tryptophan; Mitochondrial; Apoptosis; Energy Metabolism - methane; Oxidoreductase; EC 1.11.1.6

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytosol; endoplasmic reticulum; extracellular space; focal adhesion; Golgi apparatus; intracellular membrane-bound organelle; lysosome; membrane; mitochondrial intermembrane space; mitochondrion; peroxisomal matrix; peroxisomal membrane; peroxisome; plasma membrane

Molecular Function: aminoacylase activity; antioxidant activity; catalase activity; enzyme binding; heme binding; metal ion binding; NADP binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; receptor binding

Biological Process: activation of NF-kappaB transcription factor; aerobic respiration; aging; cholesterol metabolic process; hemoglobin metabolic process; hydrogen peroxide catabolic process; inhibition of NF-kappaB transcription factor; negative regulation of apoptosis; osteoblast differentiation; positive regulation of cell division; positive regulation of phosphoinositide 3-kinase cascade; protein homotetramerization; protein tetramerization; purine nucleotide catabolic process; response to activity; response to cadmium ion; response to drug; response to estradiol stimulus; response to ethanol; response to hydrogen peroxide; response to hyperoxia; response to hypoxia; response to inactivity; response to insulin stimulus; response to L-ascorbic acid; response to lead ion; response to light intensity; response to ozone; response to reactive oxygen species; response to vitamin A; response to vitamin E; triacylglycerol metabolic process; ureteric bud development; UV protection

Disease: Acatalasemia
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 Research Articles on CAT    1. no significant correlations found between fertility and semen catalase activity
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CAT peptidePathways associated with CAT peptide
 Reference Product  PubMed Publications
 SOD1 peptide  >312 publications with CAT and SOD1
 SOD2 peptide  >236 publications with CAT and SOD2
 GSR peptide  >57 publications with CAT and GSR
 SOD3 peptide  >35 publications with CAT and SOD3
 AKT1 peptide  >15 publications with CAT and AKT1
 FOXO3 peptide  >12 publications with CAT and FOXO3
 XDH peptide  >11 publications with CAT and XDH
 PEX5 peptide  >1 publications with CAT and PEX5
 Products by Pathway  Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
Diseases associated with CAT peptideOrgans/Tissues associated with CAT peptide
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1511 publications with CAT and Necrosis
 Asthma Antibodies  >1406 publications with CAT and Asthma
 Diabetes Mellitus Antibodies  >1356 publications with CAT and Diabetes Mellitus
 Hypertension Antibodies  >939 publications with CAT and Hypertension
 Edema Antibodies  >771 publications with CAT and Edema
 Seizures Antibodies  >736 publications with CAT and Seizures
 Disease Progression Antibodies  >706 publications with CAT and Disease Progression
 Brain Ischemia Antibodies  >590 publications with CAT and Brain Ischemia
 Heart Failure Antibodies  >563 publications with CAT and Heart Failure
 Reperfusion Injury Antibodies  >506 publications with CAT and Reperfusion Injury
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >23810 publications with CAT and Brain
 Blood Antibodies  >17675 publications with CAT and Blood
 Nerve Antibodies  >10650 publications with CAT and Nerve
 Muscle Antibodies  >9966 publications with CAT and Muscle
 Eye Antibodies  >6056 publications with CAT and Eye
 Liver Antibodies  >5332 publications with CAT and Liver
 Heart Antibodies  >5180 publications with CAT and Heart
 Vascular Antibodies  >5177 publications with CAT and Vascular
 Skin Antibodies  >4504 publications with CAT and Skin
 Kidney Antibodies  >3578 publications with CAT and Kidney
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