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DCP1A peptide

Scan QR to view Datasheet Catalog #    MBS425267 DCP1A peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

DCP1A, Peptide

 Also Known As   

DCP1A Immunizing Peptide

 Product Synonym Names    DCP1A; decapping enzyme; HSA275986; Nbla00360; SMAD4IP1; SMIF; Smad4-interacting transcriptional co-activator; decapping enzyme hDcp1a; putative protein product of Nbla00360; transcription factor SMIF
 Product Gene Name   

DCP1A peptide

[Similar Products]
 Antibody/Peptide Pairs    DCP1A peptide (MBS425267) is used for blocking the activity of DCP1A antibody (MBS420474)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-QVLTKNKD NHN
 OMIM    607010
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 Species Reactivity    Human, Mouse, Rat
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of DCP1A peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for DCP1A. It may not necessarily be applicable to this product.
 NCBI GI #    84662781
 NCBI GeneID    55802
 NCBI Accession #    NP_060873.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_018403.4 [Other Products]
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 UniProt Secondary Accession #    B4DHN9; U3KQM8 [Other Products]
 UniProt Related Accession #    Q9NPI6 [Other Products]
 Molecular Weight    59,361 Da
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 NCBI Official Full Name    mRNA-decapping enzyme 1A
 NCBI Official Synonym Full Names    decapping mRNA 1A
 NCBI Official Symbol    DCP1A [Similar Products]
 NCBI Official Synonym Symbols   
SMIF; SMAD4IP1; HSA275986; Nbla00360
[Similar Products]
 NCBI Protein Information    mRNA-decapping enzyme 1A
 UniProt Protein Name    mRNA-decapping enzyme 1A
 UniProt Synonym Protein Names   
Smad4-interacting transcriptional co-activator; Transcription factor SMIF
 Protein Family    mRNA-decapping enzyme
 UniProt Gene Name    DCP1A [Similar Products]
 UniProt Synonym Gene Names    SMIF [Similar Products]
 UniProt Entry Name    DCP1A_HUMAN
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 NCBI Summary for DCP1A    Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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 UniProt Comments for DCP1A    DCP1A: a decapping enzyme. Plays a role in general and regulated mRNA decay. Apparently plays a role in the nonsense-mediated decay pathway that rids cells of mRNAs containing premature termination codons. May function as a transactivator of SMAD4 that participates in TGF-beta signaling.

Protein type: EC 3.-.-.-; Transcription, coactivator/corepressor; Hydrolase; RNA processing

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; membrane; nucleus

Molecular Function: enzyme activator activity; enzyme regulator activity; hydrolase activity; identical protein binding; mRNA binding; protein binding

Biological Process: deadenylation-dependent decapping; deadenylation-independent decapping; mRNA catabolic process, nonsense-mediated decay; positive regulation of catalytic activity; regulation of mRNA stability
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 Research Articles on DCP1A    1. The assembly of EDC4 and Dcp1a into processing bodies is critical for the translational regulation of IL-6.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with DCP1A peptideDiseases associated with DCP1A peptide
 Products by Pathway  Pathway Diagram
 Butyrate Response Factor 1 (BRF1) Binds And Destabilizes MRNA Pathway antibodies  Butyrate Response Factor 1 (BRF1) Binds And Destabilizes MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Decapping Complex Pathway antibodies  Decapping Complex Pathway Diagram
 Decapping Complex Pathway antibodies  Decapping Complex Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies  Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
 Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies  Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with DCP1A and Necrosis
 Inflammation Antibodies  >2 publications with DCP1A and Inflammation
 Infertility, Female Antibodies  >1 publications with DCP1A and Infertility, Female
 Neurobehavioral Manifestations Antibodies  >1 publications with DCP1A and Neurobehavioral Manifestations
 Congenital Abnormalities Antibodies  >1 publications with DCP1A and Congenital Abnormalities
 Adenocarcinoma Antibodies  >1 publications with DCP1A and Adenocarcinoma
 Kidney Diseases Antibodies  >1 publications with DCP1A and Kidney Diseases
Organs/Tissues associated with DCP1A peptide
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with DCP1A and Brain
 Blood Antibodies  >3 publications with DCP1A and Blood
 Liver Antibodies  >3 publications with DCP1A and Liver
 Kidney Antibodies  >2 publications with DCP1A and Kidney
 Ovary Antibodies  >2 publications with DCP1A and Ovary
 Heart Antibodies  >2 publications with DCP1A and Heart
 Stomach Antibodies  >1 publications with DCP1A and Stomach
 Nerve Antibodies  >1 publications with DCP1A and Nerve
 Bone Antibodies  >1 publications with DCP1A and Bone
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