NP_001032757.2
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,846 Da
NCBI Official Full Name
beta-defensin 107
NCBI Official Synonym Full Names
defensin beta 107A
NCBI Protein Information
beta-defensin 107
UniProt Protein Name
Beta-defensin 107
UniProt Synonym Protein Names
Beta-defensin 7; BD-7; DEFB-7; Defensin, beta 107
UniProt Synonym Gene Names
UniProt Entry Name
D107A_HUMAN
NCBI Summary for DEFB107A
Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]
UniProt Comments for DEFB107A
DEFB107A: Has antibacterial activity (Potential). Belongs to the beta-defensin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 8p23.1
Cellular Component: extracellular region
Biological Process: defense response to bacterium
Research Articles on DEFB107A
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Pathways associated with DEFB107A blocking peptide
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