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EHD2 peptide

Scan QR to view Datasheet Catalog #    MBS426788 EHD2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

EHD2, Peptide

 Also Known As   

EHD2 Immunizing Peptide

 Product Synonym Names    EHD2; PAST2; EH-domain containing 2; EH domain containing 2; FLJ96617
 Product Gene Name   

EHD2 peptide

[Similar Products]
 Antibody/Peptide Pairs    EHD2 peptide (MBS426788) is used for blocking the activity of EHD2 antibody (MBS420993)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    CRLVPPSKRR HKGSA
 OMIM    605890
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 Species Reactivity    Human, Mouse, Rat, Dog, Cow
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of EHD2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for EHD2. It may not necessarily be applicable to this product.
 NCBI GI #    21361462
 NCBI GeneID    30846
 NCBI Accession #    NP_055416.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014601.3 [Other Products]
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 UniProt Secondary Accession #    Q96CB6; B2RDH9; B4DNU6 [Other Products]
 UniProt Related Accession #    Q9NZN4 [Other Products]
 Molecular Weight    46,059 Da
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 NCBI Official Full Name    EH domain-containing protein 2
 NCBI Official Synonym Full Names    EH domain containing 2
 NCBI Official Symbol    EHD2 [Similar Products]
 NCBI Official Synonym Symbols   
PAST2
[Similar Products]
 NCBI Protein Information    EH domain-containing protein 2
 UniProt Protein Name    EH domain-containing protein 2
 UniProt Synonym Protein Names   
PAST homolog 2Curated
 Protein Family    EH domain-containing protein
 UniProt Gene Name    EHD2 [Similar Products]
 UniProt Entry Name    EHD2_HUMAN
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 NCBI Summary for EHD2    This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway. [provided by RefSeq, Jul 2008]
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 UniProt Comments for EHD2    EHD2: Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: caveola; cytosol; endosome membrane; extrinsic to membrane; nucleus; perinuclear region of cytoplasm; plasma membrane; recycling endosome membrane

Molecular Function: ATP binding; calcium ion binding; GTP binding; hydrolase activity; nucleic acid binding; protein binding; protein domain specific binding

Biological Process: blood coagulation; cortical actin cytoskeleton organization and biogenesis; endocytic recycling; endocytosis; metabolic process
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 Research Articles on EHD2    1. Data suggest that the EH-domain containing 2 protein (EHD2) NPF phenylalanine residue is crucial for EHD2 localization to the plasma membrane, whereas the proline residue is essential for EHD2 dimerization and binding.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EHD2 peptidePathways associated with EHD2 peptide
 Reference Product  PubMed Publications
 EHD1 peptide  >28 publications with EHD2 and EHD1
 EHD3 peptide  >15 publications with EHD2 and EHD3
 PACSIN2 peptide  >8 publications with EHD2 and PACSIN2
 EHBP1 peptide  >6 publications with EHD2 and EHBP1
 SLC2A4 peptide  >2 publications with EHD2 and SLC2A4
 MYOF peptide  >1 publications with EHD2 and MYOF
 Products by Pathway  Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
Diseases associated with EHD2 peptideOrgans/Tissues associated with EHD2 peptide
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >3 publications with EHD2 and Breast Neoplasms
 Nervous System Diseases Antibodies  >2 publications with EHD2 and Nervous System Diseases
 Ovarian Neoplasms Antibodies  >2 publications with EHD2 and Ovarian Neoplasms
 Disease Models, Animal Antibodies  >2 publications with EHD2 and Disease Models, Animal
 Intracranial Hemorrhages Antibodies  >1 publications with EHD2 and Intracranial Hemorrhages
 Myocardial Infarction Antibodies  >1 publications with EHD2 and Myocardial Infarction
 Prostatic Diseases Antibodies  >1 publications with EHD2 and Prostatic Diseases
 Neoplasm Metastasis Antibodies  >1 publications with EHD2 and Neoplasm Metastasis
 Hyperplasia Antibodies  >1 publications with EHD2 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >9 publications with EHD2 and Muscle
 Brain Antibodies  >6 publications with EHD2 and Brain
 Vascular Antibodies  >2 publications with EHD2 and Vascular
 Heart Antibodies  >2 publications with EHD2 and Heart
 Connective Tissue Antibodies  >2 publications with EHD2 and Connective Tissue
 Adipose Tissue Antibodies  >2 publications with EHD2 and Adipose Tissue
 Stomach Antibodies  >1 publications with EHD2 and Stomach
 Prostate Antibodies  >1 publications with EHD2 and Prostate
 Pancreas Antibodies  >1 publications with EHD2 and Pancreas
 Kidney Antibodies  >1 publications with EHD2 and Kidney
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