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ESRRG peptide

Scan QR to view Datasheet Catalog #    MBS425432 ESRRG peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ESRRG, Peptide

 Also Known As   

ESRRG Immunizing Peptide

 Product Synonym Names    ESRRG; DKFZp781L1617; Estrogen-related receptor gamma; ERR3; FLJ16023; KIAA0832; NR3B3
 Product Gene Name   

ESRRG peptide

[Similar Products]
 Antibody/Peptide Pairs    ESRRG peptide (MBS425432) is used for blocking the activity of ESRRG antibody (MBS421601)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    CRMSNKDRHI DS
 OMIM    602969
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 Species Reactivity    Human, Mouse, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of ESRRG peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for ESRRG. It may not necessarily be applicable to this product.
 NCBI GI #    45545433
 NCBI GeneID    2104
 NCBI Accession #    NP_001429.2 [Other Products]
 NCBI Related Accession #    NP_996317.1; NP_996318.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001438.3 [Other Products]
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 UniProt Secondary Accession #    O75454; O96021; Q68DA0; Q6P274; Q6PK28; Q6TS38; A8K4I0; A8K6I2; B3KY84; E9PGB7; F8W8J3 [Other Products]
 UniProt Related Accession #    P62508 [Other Products]
 Molecular Weight    52,462 Da
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 NCBI Official Full Name    estrogen-related receptor gamma isoform 1
 NCBI Official Synonym Full Names    estrogen related receptor gamma
 NCBI Official Symbol    ESRRG [Similar Products]
 NCBI Official Synonym Symbols   
ERR3; NR3B3; ERRgamma
[Similar Products]
 NCBI Protein Information    estrogen-related receptor gamma
 UniProt Protein Name    Estrogen-related receptor gamma
 UniProt Synonym Protein Names   
ERR gamma-2; Estrogen receptor-related protein 3; Nuclear receptor subfamily 3 group B member 3
 Protein Family    Estrogen-related receptor
 UniProt Gene Name    ESRRG [Similar Products]
 UniProt Synonym Gene Names    ERR3; ERRG2; KIAA0832; NR3B3 [Similar Products]
 UniProt Entry Name    ERR3_HUMAN
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 NCBI Summary for ESRRG    This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011]
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 UniProt Comments for ESRRG    ERR3: Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. Belongs to the nuclear hormone receptor family. NR3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; Nuclear receptor; DNA-binding

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: nucleoplasm

Molecular Function: AF-2 domain binding; protein binding; retinoic acid receptor activity; steroid binding; steroid hormone receptor activity; zinc ion binding

Biological Process: positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; retinoic acid receptor signaling pathway; steroid hormone mediated signaling; transcription initiation from RNA polymerase II promoter
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 Research Articles on ESRRG    1. Data show that micrRNA miR-320a directly targets cAMP-regulated phosphoprotein 19 (ARPP-19) and estrogen-related receptor gamma protein (ERRgamma) in breast cancer cell lines.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with ESRRG peptidePathways associated with ESRRG peptide
 Reference Product  PubMed Publications
 PPARGC1A peptide  >16 publications with ESRRG and PPARGC1A
 PPARGC1B peptide  >3 publications with ESRRG and PPARGC1B
 NR0B2 peptide  >2 publications with ESRRG and NR0B2
 PNRC2 peptide  >1 publications with ESRRG and PNRC2
 ESRRA peptide  >1 publications with ESRRG and ESRRA
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
Diseases associated with ESRRG peptideOrgans/Tissues associated with ESRRG peptide
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >16 publications with ESRRG and Breast Neoplasms
 Adenocarcinoma Antibodies  >12 publications with ESRRG and Adenocarcinoma
 Liver Diseases Antibodies  >9 publications with ESRRG and Liver Diseases
 Cardiovascular Diseases Antibodies  >9 publications with ESRRG and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >6 publications with ESRRG and Disease Models, Animal
 Liver Neoplasms Antibodies  >4 publications with ESRRG and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with ESRRG and Carcinoma, Hepatocellular
 Ovarian Neoplasms Antibodies  >4 publications with ESRRG and Ovarian Neoplasms
 Vascular Diseases Antibodies  >4 publications with ESRRG and Vascular Diseases
 Prostatic Neoplasms Antibodies  >4 publications with ESRRG and Prostatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >30 publications with ESRRG and Muscle
 Heart Antibodies  >20 publications with ESRRG and Heart
 Brain Antibodies  >19 publications with ESRRG and Brain
 Kidney Antibodies  >17 publications with ESRRG and Kidney
 Embryonic Tissue Antibodies  >9 publications with ESRRG and Embryonic Tissue
 Placenta Antibodies  >8 publications with ESRRG and Placenta
 Uterus Antibodies  >4 publications with ESRRG and Uterus
 Testis Antibodies  >2 publications with ESRRG and Testis
 Mammary Gland Antibodies  >1 publications with ESRRG and Mammary Gland
 Intestine Antibodies  >1 publications with ESRRG and Intestine
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