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EN2 peptide :: Engrailed-2 Peptide

Scan QR to view Datasheet Catalog #    MBS425896 EN2 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Engrailed-2 (EN2), Peptide

 Also Known As   

Engrailed-2 Immunizing Peptide

 Product Synonym Names    Engrailed-2; engrailed homolog 2; EN2; AUTS1; Engrailed-2; Engrailed-2
 Product Gene Name   

EN2 peptide

[Similar Products]
 Antibody/Peptide Pairs    Engrailed-2 peptide (MBS425896) is used for blocking the activity of Engrailed-2 antibody (MBS421385)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    131310
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 Species Reactivity    Human, Mouse, Rat, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of EN2 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for EN2. It may not necessarily be applicable to this product.
 NCBI GI #    7710121
 NCBI GeneID    2020
 NCBI Accession #    NP_001418.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001427.3 [Other Products]
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 UniProt Secondary Accession #    Q549U3; Q9UD58; A4D252 [Other Products]
 UniProt Related Accession #    P19622 [Other Products]
 Molecular Weight    34,211 Da
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 NCBI Official Full Name    homeobox protein engrailed-2
 NCBI Official Synonym Full Names    engrailed homeobox 2
 NCBI Official Symbol    EN2 [Similar Products]
 NCBI Protein Information    homeobox protein engrailed-2
 UniProt Protein Name    Homeobox protein engrailed-2
 Protein Family    Homeobox protein
 UniProt Gene Name    EN2 [Similar Products]
 UniProt Synonym Gene Names    Homeobox protein en-2; Hu-En-2 [Similar Products]
 UniProt Entry Name    HME2_HUMAN
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 NCBI Summary for EN2    Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]
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 UniProt Comments for EN2    En-2: Genetic variations in EN2 may be associated with susceptibility to autism. Belongs to the engrailed homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 7q36

Cellular Component: membrane; nucleus

Molecular Function: sequence-specific DNA binding

Biological Process: hindbrain development; midbrain development; multicellular organismal development; negative regulation of neuron apoptosis; neuron development; positive regulation of transcription from RNA polymerase II promoter

Disease: Autism, Susceptibility To, 10
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 Research Articles on EN2    1. EN2 may be a candidate oncogene in bladder cancer by activating the PI3K/Akt pathway and inhibiting PTEN.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with EN2 peptideDiseases associated with EN2 peptide
 Reference Product  PubMed Publications
 FGF8 peptide  >18 publications with EN2 and FGF8
 WNT1 peptide  >15 publications with EN2 and WNT1
 SHH peptide  >15 publications with EN2 and SHH
 WNT3A peptide  >3 publications with EN2 and WNT3A
 EGR2 peptide  >2 publications with EN2 and EGR2
 ZIC1 peptide  >2 publications with EN2 and ZIC1
 DHH peptide  >1 publications with EN2 and DHH
 CNPY1 peptide  >1 publications with EN2 and CNPY1
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >33 publications with EN2 and Nervous System Diseases
 Autism Spectrum Disorder Antibodies  >23 publications with EN2 and Autism Spectrum Disorder
 Autistic Disorder Antibodies  >22 publications with EN2 and Autistic Disorder
 Death Antibodies  >17 publications with EN2 and Death
 Brain Diseases Antibodies  >13 publications with EN2 and Brain Diseases
 Disease Models, Animal Antibodies  >12 publications with EN2 and Disease Models, Animal
 Abnormalities, Multiple Antibodies  >10 publications with EN2 and Abnormalities, Multiple
 Learning Disorders Antibodies  >8 publications with EN2 and Learning Disorders
 Neurobehavioral Manifestations Antibodies  >7 publications with EN2 and Neurobehavioral Manifestations
 Neurodegenerative Diseases Antibodies  >5 publications with EN2 and Neurodegenerative Diseases
Organs/Tissues associated with EN2 peptide
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >93 publications with EN2 and Brain
 Intestine Antibodies  >2 publications with EN2 and Intestine
 Mammary Gland Antibodies  >1 publications with EN2 and Mammary Gland
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