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FBXL12 peptide

Scan QR to view Datasheet Catalog #    MBS425794 FBXL12 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

FBXL12, Peptide

 Also Known As   

FBXL12 Immunizing Peptide

 Product Synonym Names    FBXL12; likely ortholog of mouse f-box and leucine-rich repeat protein 12; FLJ20188; hypothetical protein FLJ20188; F-box and leucine-rich repeat protein 12; Fbl12
 Product Gene Name   

FBXL12 peptide

[Similar Products]
 Antibody/Peptide Pairs    FBXL12 peptide (MBS425794) is used for blocking the activity of FBXL12 antibody (MBS420229)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    RACPKESMDW WM
 OMIM    609079
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 Species Reactivity    Human, Mouse, Rat, Dog
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of FBXL12 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for FBXL12. It may not necessarily be applicable to this product.
 NCBI GI #    8923179
 NCBI GeneID    54850
 NCBI Accession #    NP_060173.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_017703.2 [Other Products]
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 UniProt Secondary Accession #    Q9H5K4; B3KSJ8 [Other Products]
 UniProt Related Accession #    Q9NXK8 [Other Products]
 Molecular Weight    30,491 Da
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 NCBI Official Full Name    F-box/LRR-repeat protein 12 isoform a
 NCBI Official Synonym Full Names    F-box and leucine-rich repeat protein 12
 NCBI Official Symbol    FBXL12 [Similar Products]
 NCBI Official Synonym Symbols   
Fbl12
[Similar Products]
 NCBI Protein Information    F-box/LRR-repeat protein 12
 UniProt Protein Name    F-box/LRR-repeat protein 12
 UniProt Synonym Protein Names   
F-box and leucine-rich repeat protein 12; F-box protein FBL12
 UniProt Gene Name    FBXL12 [Similar Products]
 UniProt Synonym Gene Names    FBL12 [Similar Products]
 UniProt Entry Name    FXL12_HUMAN
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 NCBI Summary for FBXL12    Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for FBXL12    FBXL12: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: cytoplasm; ubiquitin ligase complex

Molecular Function: protein binding

Biological Process: protein ubiquitination; ubiquitin-dependent protein catabolic process
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 Research Articles on FBXL12    1. Fbxl12-induced CaMKI degradation attenuates p27 phosphorylation at these sites in early G1 and iii) activation of CaMKI during G1 transition followed by p27 phosphorylation appears to be upstream to other p27 phosphorylation events
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Organs/Tissues associated with FBXL12 peptide
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >2 publications with FBXL12 and Embryonic Tissue
 Placenta Antibodies  >2 publications with FBXL12 and Placenta
 Bone Antibodies  >1 publications with FBXL12 and Bone
 Bone Marrow Antibodies  >1 publications with FBXL12 and Bone Marrow
 Liver Antibodies  >1 publications with FBXL12 and Liver
 Connective Tissue Antibodies  >1 publications with FBXL12 and Connective Tissue
 Thymus Antibodies  >1 publications with FBXL12 and Thymus
 Lung Antibodies  >1 publications with FBXL12 and Lung
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