View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List FYB blocking peptide Catalog # MBS427962 Unit / Price 0.1 mg / $240 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name FYB, Blocking Peptide Full Product Name FYB Immunizing Peptide Product Synonym Names FYB; FYN binding protein (FYB-120/130); ADAP; PRO0823; SLAP-130; FYN-binding protein (FYB-120/130); adhesion and degranulation-promoting adaptor protein Product Gene Name FYB blocking peptide[Similar Products] Antibody/Peptide Pairs FYB peptide (MBS427962) is used for blocking the activity of FYB antibody (MBS423056) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Important Note This blocking peptide is designed to be used with its corresponding antibody. If the corresponding antibody is not noted on this datasheet then please contact our technical support team. We do not guarantee that this antibody will work with other antibodies/applications. Sequence C-SEEKPDKE PKP OMIM 602731 Species Reactivity Human, Dog, Cow Form/Format 100ug of dried peptide Preparation and Storage Shipped at ambient temperature, store at -20 degree C ISO Certification Manufactured in an ISO 9001:2008 Certified Laboratory. Other Notes Small volumes of FYB blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP NCBI/Uniprot data below describe general gene information for FYB. It may not necessarily be applicable to this product. NCBI GI # 42476118 NCBI GeneID 2533 NCBI Accession # NP_001456.3 [Other Products] NCBI Related Accession # Manufactured in an ISO 9001:2008 Certified Laboratory.NP_955367.1; NP_001230022.1[Other Products] NCBI GenBank Nucleotide # NM_001465.4 [Other Products] UniProt Secondary Accession # O00359; Q9NZI9; A8K2Y8; B4DLN2; E9PBV9[Other Products] UniProt Related Accession # O15117[Other Products] Molecular Weight 91,651 Da TOP NCBI Official Full Name FYN-binding protein isoform 1 NCBI Official Synonym Full Names FYN binding protein NCBI Official Symbol FYB [Similar Products] NCBI Official Synonym Symbols ADAP; PRO0823; SLAP130; SLAP-130 [Similar Products] NCBI Protein Information FYN-binding protein UniProt Protein Name FYN-binding protein UniProt Synonym Protein Names Adhesion and degranulation promoting adaptor protein; ADAP; FYB-120/130; p120/p130; FYN-T-binding protein; SLAP-130; SLP-76-associated phosphoprotein Protein Family FYN-binding protein UniProt Gene Name FYB [Similar Products] UniProt Synonym Gene Names SLAP130; ADAP; p120/p130 [Similar Products] UniProt Entry Name FYB_HUMAN TOP NCBI Summary for FYB The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] TOP UniProt Comments for FYB SLAP-130: an adapter protein for fyn and the SH2-domain-containing leucocyte protein-76 (SLP76) in T cells. T-cell receptor ligation leads to increased tyrosine phosphorylation of SLAP-130. Two alternatively spliced isoforms have been described.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: 5p13.1Cellular Component: actin cytoskeleton; cytosol; nucleus; plasma membraneMolecular Function: protein binding; protein complex binding; receptor bindingBiological Process: immune response; NLS-bearing substrate import into nucleus; protein amino acid phosphorylation; signal transduction; T cell receptor signaling pathway Research Articles on FYB 1. FYB nonsense mutations in humans causing small-platelet thrombocytopenia and a significant bleeding tendency. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Pathways associated with FYB blocking peptide Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Cell-Cell Communication Pathway antibodies Cell-Cell Communication Pathway Diagram Generation Of Second Messenger Molecules Pathway antibodies Generation Of Second Messenger Molecules Pathway Diagram Immune System Pathway antibodies Immune System Pathway Diagram Rap1 Signaling Pathway antibodies Rap1 Signaling Pathway Diagram Rap1 Signaling Pathway antibodies Rap1 Signaling Pathway Diagram Signal Regulatory Protein (SIRP) Family Interactions Pathway antibodies Signal Regulatory Protein (SIRP) Family Interactions Pathway Diagram TCR Signaling Pathway antibodies TCR Signaling Pathway Diagram TCR Signaling Pathway antibodies TCR Signaling Pathway Diagram TCR Signaling In Naive CD4+ T Cells Pathway antibodies TCR Signaling In Naive CD4+ T Cells Pathway Diagram Diseases associated with FYB blocking peptide Disease Name Pubmed Publications Anemia Antibodies >16 publications with FYB and Anemia Inflammation Antibodies >11 publications with FYB and Inflammation Skin Diseases Antibodies >4 publications with FYB and Skin Diseases Kidney Diseases Antibodies >3 publications with FYB and Kidney Diseases Lung Diseases Antibodies >3 publications with FYB and Lung Diseases Breast Neoplasms Antibodies >3 publications with FYB and Breast Neoplasms Neoplasm Metastasis Antibodies >2 publications with FYB and Neoplasm Metastasis Cell Transformation, Neoplastic Antibodies >2 publications with FYB and Cell Transformation, Neoplastic Acute Kidney Injury Antibodies >2 publications with FYB and Acute Kidney Injury Necrosis Antibodies >2 publications with FYB and Necrosis Organs/Tissues associated with FYB blocking peptide Organ/Tissue Name Pubmed Publications Blood Antibodies >214 publications with FYB and Blood Bone Marrow Antibodies >11 publications with FYB and Bone Marrow Vascular Antibodies >9 publications with FYB and Vascular Kidney Antibodies >8 publications with FYB and Kidney Spleen Antibodies >7 publications with FYB and Spleen Lung Antibodies >6 publications with FYB and Lung Heart Antibodies >6 publications with FYB and Heart Brain Antibodies >5 publications with FYB and Brain Lymph Node Antibodies >5 publications with FYB and Lymph Node Thymus Antibodies >4 publications with FYB and Thymus TOP © 2006-24 MyBioSource.com. 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