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TRIM8 peptide :: GERP / TRIM8 Peptide

Scan QR to view Datasheet Catalog #    MBS426744 TRIM8 peptide
Unit / Price
0.1 mg  /  $190 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

GERP / TRIM8, Peptide

 Also Known As   

GERP / TRIM8 Immunizing Peptide

 Product Synonym Names    TRIM8; tripartite motif-containing 8; GERP; RNF27; ring finger protein 27; tripartite motif protein TRIM8; glioblastoma expressed ring finger protein; RP11-47A8.4; GERP / TRIM8
 Product Gene Name   

TRIM8 peptide

[Similar Products]
 Product Synonym Gene Name    GERP [Similar Products]
 Antibody/Peptide Pairs    GERP / TRIM8 peptide (MBS426744) is used for blocking the activity of GERP/TRIM8 antibody (MBS420230)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Sequence    C-YGQPSTKH YVTS
 OMIM    606125
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 Species Reactivity    Human, Mouse, Rat, Dog, Pig
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 Form/Format    100ug of dried peptide
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 Preparation and Storage    Shipped at ambient temperature, store at -20 degree C
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of TRIM8 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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NCBI/Uniprot data below describe general gene information for TRIM8. It may not necessarily be applicable to this product.
 NCBI GI #    148596968
 NCBI GeneID    81603
 NCBI Accession #    NP_112174.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_030912.2 [Other Products]
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 UniProt Secondary Accession #    Q9C028; A6NI31 [Other Products]
 UniProt Related Accession #    Q9BZR9 [Other Products]
 Molecular Weight    61,489 Da
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 NCBI Official Full Name    probable E3 ubiquitin-protein ligase TRIM8
 NCBI Official Synonym Full Names    tripartite motif containing 8
 NCBI Official Symbol    TRIM8 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    probable E3 ubiquitin-protein ligase TRIM8
 UniProt Protein Name    Probable E3 ubiquitin-protein ligase TRIM8
 UniProt Synonym Protein Names   
Glioblastoma-expressed RING finger protein; RING finger protein 27; Tripartite motif-containing protein 8
 Protein Family    Probable E3 ubiquitin-protein ligase
 UniProt Gene Name    TRIM8 [Similar Products]
 UniProt Synonym Gene Names    GERP; RNF27 [Similar Products]
 UniProt Entry Name    TRIM8_HUMAN
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 NCBI Summary for TRIM8    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TRIM8    TRIM8: Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1. Belongs to the TRIM/RBCC family.

Protein type: Ubiquitin conjugating system; EC 6.3.2.-; Ligase; Ubiquitin ligase

Chromosomal Location of Human Ortholog: 10q24.3

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm; PML body

Molecular Function: identical protein binding; ligase activity; protein homodimerization activity; zinc ion binding

Biological Process: activation of NF-kappaB transcription factor; innate immune response; negative regulation of viral transcription; negative regulation of virion penetration into host cell; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription factor activity; protein ubiquitination; stem cell maintenance
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 Research Articles on TRIM8    1. Our study provides evidences that TRIM8 may participate in the carcinogenesis and progression of glioma and that the transcriptional repression of TRIM8 might have potential value for predicting poor prognosis in glioma patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TRIM8 peptidePathways associated with TRIM8 peptide
 Reference Product  PubMed Publications
 HSP90AB1 peptide  >1 publications with TRIM8 and HSP90AB1
 SOCS1 peptide  >1 publications with TRIM8 and SOCS1
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Interferon Signaling Pathway antibodies  Interferon Signaling Pathway Diagram
 Interferon Gamma Signaling Pathway antibodies  Interferon Gamma Signaling Pathway Diagram
Diseases associated with TRIM8 peptideOrgans/Tissues associated with TRIM8 peptide
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >3 publications with TRIM8 and Necrosis
 Carcinoma Antibodies  >2 publications with TRIM8 and Carcinoma
 Inflammation Antibodies  >2 publications with TRIM8 and Inflammation
 Neoplasm Metastasis Antibodies  >1 publications with TRIM8 and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >1 publications with TRIM8 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with TRIM8 and Brain
 Kidney Antibodies  >3 publications with TRIM8 and Kidney
 Embryonic Tissue Antibodies  >2 publications with TRIM8 and Embryonic Tissue
 Blood Antibodies  >1 publications with TRIM8 and Blood
 Spleen Antibodies  >1 publications with TRIM8 and Spleen
 Liver Antibodies  >1 publications with TRIM8 and Liver
 Placenta Antibodies  >1 publications with TRIM8 and Placenta
 Larynx Antibodies  >1 publications with TRIM8 and Larynx
 Lung Antibodies  >1 publications with TRIM8 and Lung
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